Name

COL17A1 Gene

collagen, type XVII, alpha 1

This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]

col17a1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term col17a1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

COL17A1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for COL17A1 from the Pathway Commons Protein-Protein Interactions dataset.