BIRC7 Gene

baculoviral IAP repeat containing 7

This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]

birc7 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term birc7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BIRC7 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BIRC7 from the Pathway Commons Protein-Protein Interactions dataset.