Name

ATP6V0D1 Gene

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008]

atp6v0d1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term atp6v0d1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ATP6V0D1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ATP6V0D1 from the Pathway Commons Protein-Protein Interactions dataset.