ATG4B Gene

autophagy related 4B, cysteine peptidase

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

atg4b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term atg4b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ATG4B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ATG4B from the Pathway Commons Protein-Protein Interactions dataset.