Name

ASIC3 Gene

acid sensing (proton gated) ion channel 3

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]

asic3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term asic3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ASIC3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ASIC3 from the Pathway Commons Protein-Protein Interactions dataset.