Name

ARHGEF2 Gene

Rho/Rac guanine nucleotide exchange factor (GEF) 2

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]

ARHGEF28 Gene

Rho guanine nucleotide exchange factor (GEF) 28

This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]

ARHGEF25 Gene

Rho guanine nucleotide exchange factor (GEF) 25

Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

ARHGEF26 Gene

Rho guanine nucleotide exchange factor (GEF) 26

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

ARHGEF26-AS1 Gene

ARHGEF26 antisense RNA 1

ARHGEF2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF2 from the Pathway Commons Protein-Protein Interactions dataset.

BL7720 (ARHGEF2) Gene Set

From NURSA Protein Complexes

proteins in the BL7720 (ARHGEF2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

ARHGEF25 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for ARHGEF25 from the NURSA Protein-Protein Interactions dataset.

ARHGEF28 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF28 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF25 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF25 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF26 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF26 from the Pathway Commons Protein-Protein Interactions dataset.