Name

ADCY6 Gene

adenylate cyclase 6

This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015]

adcy6 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term adcy6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ADCY6 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ADCY6 from the Pathway Commons Protein-Protein Interactions dataset.