ACTA1 Gene

actin, alpha 1, skeletal muscle

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]

ACTA1 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein ACTA1 from the curated Hub Proteins Protein-Protein Interactions dataset.

ACTA1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ACTA1 from the Pathway Commons Protein-Protein Interactions dataset.