Name

ABCG2 Gene

ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

abcg2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term abcg2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ABCG2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ABCG2 from the Pathway Commons Protein-Protein Interactions dataset.

Abcg5-Abcg2 complex Gene Set

From CORUM Protein Complexes

proteins in the Abcg5-Abcg2 complex protein complex from the CORUM Protein Complexes dataset.

abcg2dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term abcg2dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

abcg2mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term abcg2mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

abcg2bcrp Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term abcg2bcrp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

abcg2overexpressing Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term abcg2overexpressing in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

abcg2abcg2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term abcg2abcg2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.