Name

MCM2 Gene

minichromosome maintenance complex component 2

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]

mcm2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mcm2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MCM2 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein MCM2 from the curated Hub Proteins Protein-Protein Interactions dataset.

MCM2 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for MCM2 from the NURSA Protein-Protein Interactions dataset.

MCM2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MCM2 from the Pathway Commons Protein-Protein Interactions dataset.

MCM2-MCM4-MCM6-MCM7 complex Gene Set

From CORUM Protein Complexes

proteins in the MCM2-MCM4-MCM6-MCM7 complex protein complex from the CORUM Protein Complexes dataset.

MCM2-MCM6-MCM7 complex Gene Set

From CORUM Protein Complexes

proteins in the MCM2-MCM6-MCM7 complex protein complex from the CORUM Protein Complexes dataset.

mcm2top2a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mcm2top2a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mcm27 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mcm27 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mcm2and Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mcm2and in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DNA replication licensing factor Mcm2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA replication licensing factor Mcm2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.