Name

CDSN Gene

corneodesmosin

This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6. [provided by RefSeq, Dec 2014]

CDS1 Gene

CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]

CDS2 Gene

CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]

cds Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cds in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MUS81-CDS1 complex Gene Set

From CORUM Protein Complexes

proteins in the MUS81-CDS1 complex protein complex from the CORUM Protein Complexes dataset.

cdspecific Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdspecific in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdsn Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdsn in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDSN Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for CDSN from the NURSA Protein-Protein Interactions dataset.

CDSN Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDSN from the Pathway Commons Protein-Protein Interactions dataset.

CDS1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDS1 from the Pathway Commons Protein-Protein Interactions dataset.

CDS2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDS2 from the Pathway Commons Protein-Protein Interactions dataset.

Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Gene Set

From Reactome Pathways

proteins participating in the Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex pathway from the Reactome Pathways dataset.