Name

CDK9 Gene

cyclin-dependent kinase 9

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]

cdk9 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdk9 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDK9 Gene Set

From KEA Substrates of Kinases

substrates of the kinase CDK9 from the curated KEA Substrates of Kinases dataset.

CDK9 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for CDK9 from the NURSA Protein-Protein Interactions dataset.

CDK9 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDK9 from the Pathway Commons Protein-Protein Interactions dataset.

CDK9 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase CDK9 from the curated PhosphoSitePlus Substrates of Kinases dataset.

POLR2A-CCNT1-CDK9-NCL-LEM6-CPSF2 complex Gene Set

From CORUM Protein Complexes

proteins in the POLR2A-CCNT1-CDK9-NCL-LEM6-CPSF2 complex protein complex from the CORUM Protein Complexes dataset.

Heterotrimeric complex (CCNT1, CDK9, GRN) Gene Set

From CORUM Protein Complexes

proteins in the Heterotrimeric complex (CCNT1, CDK9, GRN) protein complex from the CORUM Protein Complexes dataset.

Heterodimer complex (CDK9, IL6ST) Gene Set

From CORUM Protein Complexes

proteins in the Heterodimer complex (CDK9, IL6ST) protein complex from the CORUM Protein Complexes dataset.

Transcription elongation factor complex (SUPT5H, CDK9, CCNT1) Gene Set

From CORUM Protein Complexes

proteins in the Transcription elongation factor complex (SUPT5H, CDK9, CCNT1) protein complex from the CORUM Protein Complexes dataset.

cdk9cyclin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdk9cyclin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdk9cyct1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdk9cyct1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDK9_knockdown_71_GSE21751 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the CDK9_knockdown_71_GSE21751 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

CDK9_knockdown_104_GSE27869 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the CDK9_knockdown_104_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

CDK9_druginhibition_183_GSE48258 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the CDK9_druginhibition_183_GSE48258 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.