Name

CDC73 Gene

cell division cycle 73

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

cdc73 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc73 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDC73 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for CDC73 from the NURSA Protein-Protein Interactions dataset.

CDC73 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC73 from the Pathway Commons Protein-Protein Interactions dataset.

cdc73/paf1 complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the cdc73/paf1 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

cdc73/paf1 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the cdc73/paf1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

cdc73/paf1 complex Gene Set

From GO Cellular Component Annotations

proteins localized to the cdc73/paf1 complex cellular component from the curated GO Cellular Component Annotations dataset.

RNA polymerase II accessory factor, Cdc73 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the RNA polymerase II accessory factor, Cdc73 protein domain from the InterPro Predicted Protein Domain Annotations dataset.