Name

CDC7 Gene

cell division cycle 7

This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008]

CDC73 Gene

cell division cycle 73

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

cdc7 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDC7 Gene Set

From KEA Substrates of Kinases

substrates of the kinase CDC7 from the curated KEA Substrates of Kinases dataset.

CDC7 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC7 from the Pathway Commons Protein-Protein Interactions dataset.

CDC7 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase CDC7 from the curated PhosphoSitePlus Substrates of Kinases dataset.

cdc73/paf1 complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the cdc73/paf1 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

cdc73/paf1 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the cdc73/paf1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

CDC7-DBF7 complex Gene Set

From CORUM Protein Complexes

proteins in the CDC7-DBF7 complex protein complex from the CORUM Protein Complexes dataset.

cdc7dbf4 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc7dbf4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdc73 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc73 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdc7ask Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc7ask in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdc7dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc7dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDC7_knockdown_109_GSE27869 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the CDC7_knockdown_109_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

cdc73/paf1 complex Gene Set

From GO Cellular Component Annotations

proteins localized to the cdc73/paf1 complex cellular component from the curated GO Cellular Component Annotations dataset.

RNA polymerase II accessory factor, Cdc73 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the RNA polymerase II accessory factor, Cdc73 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

BL9121 (CDC7) Gene Set

From NURSA Protein Complexes

proteins in the BL9121 (CDC7) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

CDC73 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for CDC73 from the NURSA Protein-Protein Interactions dataset.

CDC73 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC73 from the Pathway Commons Protein-Protein Interactions dataset.