Name

CDC6 Gene

cell division cycle 6

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]

cdc6 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDC6 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC6 from the Pathway Commons Protein-Protein Interactions dataset.

MCM8-ORC2-CDC6 complex Gene Set

From CORUM Protein Complexes

proteins in the MCM8-ORC2-CDC6 complex protein complex from the CORUM Protein Complexes dataset.

cdc6atr Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc6atr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDC6, C-terminal domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CDC6, C-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cell division protein Cdc6/18 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cell division protein Cdc6/18 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

FACT complex subunit Spt16p/Cdc68p Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the FACT complex subunit Spt16p/Cdc68p protein domain from the InterPro Predicted Protein Domain Annotations dataset.

BL9062 (CDC6) Gene Set

From NURSA Protein Complexes

proteins in the BL9062 (CDC6) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

CDC6 association with the ORC:origin complex Gene Set

From Reactome Pathways

proteins participating in the CDC6 association with the ORC:origin complex pathway from the Reactome Pathways dataset.

CDT1 association with the CDC6:ORC:origin complex Gene Set

From Reactome Pathways

proteins participating in the CDT1 association with the CDC6:ORC:origin complex pathway from the Reactome Pathways dataset.

CDK-mediated phosphorylation and removal of Cdc6 Gene Set

From Reactome Pathways

proteins participating in the CDK-mediated phosphorylation and removal of Cdc6 pathway from the Reactome Pathways dataset.