Name

CDC25C Gene

cell division cycle 25C

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008]

CDC25B Gene

cell division cycle 25B

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]

CDC25A Gene

cell division cycle 25A

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

cdc25 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdc25 and chk1 regulatory pathway in response to dna damage Gene Set

From Biocarta Pathways

proteins participating in the cdc25 and chk1 regulatory pathway in response to dna damage pathway from the Biocarta Pathways dataset.

CDC25C Gene Set

From DEPOD Substrates of Phosphatases

substrates of the phosphatase CDC25C from the curated DEPOD Substrates of Phosphatases dataset.

CDC25B Gene Set

From DEPOD Substrates of Phosphatases

substrates of the phosphatase CDC25B from the curated DEPOD Substrates of Phosphatases dataset.

CDC25A Gene Set

From DEPOD Substrates of Phosphatases

substrates of the phosphatase CDC25A from the curated DEPOD Substrates of Phosphatases dataset.

cdc25acdk2independent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25acdk2independent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdc25c Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25c in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdc25b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdc25a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL330 (CDC25A) Gene Set

From NURSA Protein Complexes

proteins in the BL330 (CDC25A) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

EPI-1490-1 (CDC25C) Gene Set

From NURSA Protein Complexes

proteins in the EPI-1490-1 (CDC25C) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

SC-97 (CDC25A) Gene Set

From NURSA Protein Complexes

proteins in the SC-97 (CDC25A) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

CDC25B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC25B from the Pathway Commons Protein-Protein Interactions dataset.

CDC25A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC25A from the Pathway Commons Protein-Protein Interactions dataset.

CDC25C Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC25C from the Pathway Commons Protein-Protein Interactions dataset.

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set

From Reactome Pathways

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways dataset.