Name

CD1C Gene

CD1c molecule

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

cd1c Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd1c in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CD1C Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CD1C from the Pathway Commons Protein-Protein Interactions dataset.

Autosomal dominant CD11C+/CD1C+ dendritic cell deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Autosomal dominant CD11C+/CD1C+ dendritic cell deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

cd1crestricted Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd1crestricted in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cd1ccd18 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd1ccd18 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.