Name

CCDC22 Gene

coiled-coil domain containing 22

This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2013]

ccdc22 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ccdc22 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CCDC22 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC22 from the Pathway Commons Protein-Protein Interactions dataset.