Name

Roadmap Epigenomics Cell and Tissue DNA Accessibility Profiles Dataset

From Roadmap Epigenomics

DNA accessibility profiles for primary cell types and tissues

Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles Dataset

From Roadmap Epigenomics

DNA methylation profiles for primary cell types and tissues

ENCODE Histone Modification Site Profiles Dataset

From Encyclopedia of DNA Elements

histone modification profiles for cell lines

ENCODE Transcription Factor Binding Site Profiles Dataset

From Encyclopedia of DNA Elements

transcription factor binding site profiles for cell lines

ENCODE Transcription Factor Targets Dataset

From Encyclopedia of DNA Elements

target genes of transcription factors from transcription factor binding site profiles

XRCC5 Gene

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

TAM Gene

Myeloproliferative syndrome, transient (transient abnormal

ASPM Gene

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

SMUG1 Gene

single-strand-selective monofunctional uracil-DNA glycosylase 1

This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants. [provided by RefSeq, Aug 2011]

SMUG1P1 Gene

single-strand-selective monofunctional uracil-DNA glycosylase 1 pseudogene 1

MKRN2OS Gene

MKRN2 opposite strand

ATXN8OS Gene

ATXN8 opposite strand (non-protein coding)

This gene is an antisense transcript to the KLHL1 gene (homolog to the Drosophila KELCH gene); it does not itself appear to be protein coding. A TAC/TGC trinucleotide repeat expansion that is incorporated into this gene transcript, but not the KLHL1 transcript, causes spinocerebellar ataxia type 8. Presumably the expansion interferes with normal antisense function of this transcript. [provided by RefSeq, Oct 2008]

GDF5OS Gene

growth differentiation factor 5 opposite strand

HAGLROS Gene

HAGLR opposite strand (non-protein coding)

KCNQ1OT1 Gene

KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)

Human chromosomal region 11p15.5 contains two clusters of epigenetically-regulated genes that are expressed from only one chromosome in a parent-of-origin manner. Each cluster, or imprinted domain, is regulated by a functionally independent imprinting control region (ICR). The human CDKN1C/KCNQ1OT1 domain is regulated by an ICR located in an intron of KCNQ1, and contains at least eight genes that are expressed exclusively or preferentially from the maternally-inherited allele. The DNA of the ICR is specifically methylated on the maternally-inherited chromosome, and unmethylated on the paternally-inherited chromosome. The ICR contains the promoter of the KCNQ1OT1 gene that is exclusively expressed from the paternal allele. The KCNQ1OT1 transcript is the antisense to the KCNQ1 gene and is a unspliced long non-coding RNA. It interacts with chromatin and regulates transcription of multiple target genes through epigenetic modifications. The transcript is abnormally expressed from both chromosomes in most patients with Beckwith-Wiedemann syndrome, and the transcript also plays an important role in colorectal carcinogenesis. [provided by RefSeq, Apr 2012]

TYMSOS Gene

TYMS opposite strand

EMX2OS Gene

EMX2 opposite strand/antisense RNA

DNM3OS Gene

DNM3 opposite strand/antisense RNA

SLC7A6OS Gene

solute carrier family 7, member 6 opposite strand

CLLU1OS Gene

chronic lymphocytic leukemia up-regulated 1 opposite strand

ZBTB8OSP2 Gene

zinc finger and BTB domain containing 8 opposite strand pseudogene 2

FANCD2OS Gene

FANCD2 opposite strand

This gene encodes a conserved protein of unknown function. [provided by RefSeq, Jan 2013]

GHRLOS Gene

ghrelin opposite strand/antisense RNA

This gene is an antisense gene of the ghrelin/obestatin prepropeptide gene. Alternatively spliced transcript variants have been identified and they may function as non-coding regulatory RNAs. [provided by RefSeq, Jan 2013]

GRASPOS Gene

GRP1-associated scaffold protein opposite strand

GATS Gene

GATS, stromal antigen 3 opposite strand

DNAH10OS Gene

dynein, axonemal, heavy chain 10 opposite strand

TRPC5OS Gene

TRPC5 opposite strand

MYCNOS Gene

MYCN opposite strand

This gene is located on the opposite strand of v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (GeneID 4613). Transcription of this antisense gene may influence the progression of neuroblastoma by inhibiting transcription of v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog. This gene is represented as non-coding pending further experimental evidence of a protein product. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2014]

COLQ Gene

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

DIO3OS Gene

DIO3 opposite strand/antisense RNA (head to head)

The mouse and human DIO3OS and DIO3 (MIM 601038) genes overlap and are transcribed in opposite directions. The mouse Dio3 gene is imprinted from the paternal allele during fetal development, suggesting that DIO3OS is a noncoding gene that may have a role in maintaining monoallelic expression of DIO3 (Hernandez et al., 2004 [PubMed 14962667]).[supplied by OMIM, Mar 2008]

FAM120AOS Gene

family with sequence similarity 120A opposite strand

ZBTB8OSP1 Gene

zinc finger and BTB domain containing 8 opposite strand pseudogene 1

MED14OS Gene

MED14 opposite strand

ARIH2OS Gene

ariadne homolog 2 opposite strand

ZBTB8OS Gene

zinc finger and BTB domain containing 8 opposite strand

PIGBOS1 Gene

PIGB opposite strand 1

CEBPZOS Gene

CEBPZ opposite strand

WDR83OS Gene

WD repeat domain 83 opposite strand

DUX4L7 Gene

double homeobox 4 like 7

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

DUX4L6 Gene

double homeobox 4 like 6

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

DUX4L5 Gene

double homeobox 4 like 5

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

DUX4L4 Gene

double homeobox 4 like 4

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

DUX4L3 Gene

double homeobox 4 like 3

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

DUX4L2 Gene

double homeobox 4 like 2

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

DUX4L9 Gene

double homeobox 4 like 9

DUX4L8 Gene

double homeobox 4 like 8

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

LOC105369260 Gene

double homeobox protein 4-like

DOC2GP Gene

double C2-like domains, gamma, pseudogene

FCHSD1 Gene

FCH and double SH3 domains 1

FCHSD2 Gene

FCH and double SH3 domains 2

DUX4L1 Gene

double homeobox 4 like 1

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]

DUX4L17 Gene

double homeobox 4 like 17

DUX4L16 Gene

double homeobox 4 like 16

DUX4L15 Gene

double homeobox 4 like 15

DUX4L14 Gene

double homeobox 4 like 14

DUX4L13 Gene

double homeobox 4 like 13

DUX4L12 Gene

double homeobox 4 like 12

DUX4L11 Gene

double homeobox 4 like 11

DUX4L10 Gene

double homeobox 4 like 10

DUX4L19 Gene

double homeobox 4 like 19

DUX4L18 Gene

double homeobox 4 like 18

LOC400026 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene

DUX4L31 Gene

double homeobox 4 like 31, pseudogene

PRKRAP1 Gene

protein kinase, interferon-inducible double stranded RNA dependent activator pseudogene 1

LOC100287794 Gene

double homeobox protein 4-like protein 4

LOC100418693 Gene

protein kinase, interferon-inducible double stranded RNA dependent activator pseudogene

LOC100418694 Gene

protein kinase, interferon-inducible double stranded RNA dependent activator pseudogene

DUXAP10 Gene

double homeobox A pseudogene 10

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

PRKRIR Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)

DOC2A Gene

double C2-like domains, alpha

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

DOC2B Gene

double C2-like domains, beta

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells. [provided by RefSeq, Jul 2008]

LOC653541 Gene

double homeobox, 4-like

LOC101930078 Gene

double homeobox protein 4-like protein 4

PRKRA Gene

protein kinase, interferon-inducible double stranded RNA dependent activator

This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

DUX4L34 Gene

double homeobox 4 like 34, pseudogene

LOC100421246 Gene

D4, zinc and double PHD fingers family 2 pseudogene

PRKRIRP8 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 8

PRKRIRP9 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 9

PRKRIRP1 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 1

PRKRIRP2 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 2

PRKRIRP3 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 3

PRKRIRP4 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 4

PRKRIRP5 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 5

PRKRIRP6 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 6

PRKRIRP7 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 7

DUXAP8 Gene

double homeobox A pseudogene 8

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUXAP6 Gene

double homeobox A pseudogene 6

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUXAP4 Gene

double homeobox A pseudogene 4

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUXAP2 Gene

double homeobox A pseudogene 2

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUXAP3 Gene

double homeobox A pseudogene 3

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUXAP9 Gene

double homeobox A pseudogene 9

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUXAP1 Gene

double homeobox A pseudogene 1

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUX4L45 Gene

double homeobox 4 like 45, pseudogene

DUX4L20 Gene

double homeobox 4 like 20

LOC100422106 Gene

staufen double-stranded RNA binding protein 1 pseudogene

DUX4L27 Gene

double homeobox 4 like 27

STAU1 Gene

staufen double-stranded RNA binding protein 1

Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008]

LOC102724961 Gene

double homeobox protein 4-like protein 4

LOC100130134 Gene

staufen double-stranded RNA binding protein 2 pseudogene

DUX5 Gene

double homeobox 5

The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX5, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

DUX4 Gene

double homeobox 4

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

DUX1 Gene

double homeobox 1

The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX1, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

DUX3 Gene

double homeobox 3

The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX3, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

DUXA Gene

double homeobox A

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the DUXA homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]

DUXB Gene

double homeobox B

STAU2 Gene

staufen double-stranded RNA binding protein 2

Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

DZANK1 Gene

double zinc ribbon and ankyrin repeat domains 1

This gene contains two ankyrin repeat-encoding regions. Ankyrin repeats are tandemly repeated modules of about 33 amino acids described as L-shaped structures consisting of a beta-hairpin and two alpha-helices. Ankyrin repeats occur in a large number of functionally diverse proteins, mainly from eukaryotes, and are known to function as protein-protein interaction domains. Alternative splicing has been observed for this gene but the full-length nature of additional variants has not been determined. [provided by RefSeq, Jul 2008]

DPF2 Gene

D4, zinc and double PHD fingers family 2

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]

DPF3 Gene

D4, zinc and double PHD fingers, family 3

This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

DPF1 Gene

D4, zinc and double PHD fingers family 1

BDP1P Gene

B double prime 1 pseudogene

LOC100287954 Gene

double homeobox protein 4-like protein 4

LOC100419081 Gene

double homeobox A pseudogene

LOC100287823 Gene

double homeobox protein 4-like protein 4

BDP1 Gene

B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]

LOC100533853 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene

DUXAP7 Gene

double homeobox A pseudogene 7

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

DUXAP5 Gene

double homeobox A pseudogene 5

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the DUXA homeobox gene family. [provided by RefSeq, Jul 2008]

PRKRIRP10 Gene

protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) pseudogene 10

DUX4L26 Gene

double homeobox 4 like 26

DUX4L24 Gene

double homeobox 4 like 24

DUX4L25 Gene

double homeobox 4 like 25

DUX4L22 Gene

double homeobox 4 like 22

DUX4L23 Gene

double homeobox 4 like 23

DUX4L21 Gene

double homeobox 4 like 21

LOC442042 Gene

polymerase (RNA) II (DNA directed) polypeptide D pseudogene

TDG Gene

thymine-DNA glycosylase

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]

DDIT3 Gene

DNA-damage-inducible transcript 3

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]

DDIT4 Gene

DNA-damage-inducible transcript 4

TARDBPP1 Gene

TAR DNA binding protein pseudogene 1

TARDBPP2 Gene

TAR DNA binding protein pseudogene 2

DDI2 Gene

DNA-damage inducible 1 homolog 2 (S. cerevisiae)

DDI1 Gene

DNA-damage inducible 1 homolog 1 (S. cerevisiae)

N6AMT1 Gene

N-6 adenine-specific DNA methyltransferase 1 (putative)

This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014]

N6AMT2 Gene

N-6 adenine-specific DNA methyltransferase 2 (putative)

LOC102724184 Gene

DNA (cytosine-5)-methyltransferase 3-like

LOC646044 Gene

single stranded DNA binding protein 4 pseudogene

SSBP4 Gene

single stranded DNA binding protein 4

LOC100421620 Gene

polymerase (RNA) mitochondrial (DNA directed) pseudogene

LOC105377532 Gene

DNA dC->dU-editing enzyme APOBEC-3G-like

LOC100132698 Gene

single stranded DNA binding protein 4 pseudogene

TDP2 Gene

tyrosyl-DNA phosphodiesterase 2

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]

GADD45A Gene

growth arrest and DNA-damage-inducible, alpha

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]

GADD45B Gene

growth arrest and DNA-damage-inducible, beta

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]

GADD45G Gene

growth arrest and DNA-damage-inducible, gamma

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]

POLR3GP2 Gene

polymerase (RNA) III (DNA directed) polypeptide G (32kD) pseudogene 2

POLR3GP1 Gene

polymerase (RNA) III (DNA directed) polypeptide G (32kD) pseudogene 1

POLN Gene

polymerase (DNA directed) nu

This gene encodes a DNA polymerase type-A family member. The encoded protein plays a role in DNA repair and homologous recombination. This gene shares its 5' exons with some transcripts from overlapping GeneID: 79441, which encodes an augmentin-like protein complex subunit. [provided by RefSeq, Dec 2014]

POLR2CP Gene

polymerase (RNA) II (DNA directed) polypeptide C, pseudogene

CENPBD1 Gene

CENPB DNA-binding domains containing 1

DNTT Gene

DNA nucleotidylexotransferase

This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

PRIM1 Gene

primase, DNA, polypeptide 1 (49kDa)

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008]

PRIM2 Gene

primase, DNA, polypeptide 2 (58kDa)

This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene, which is also present on chromosome 6. [provided by RefSeq, Apr 2014]

LOC390250 Gene

polymerase (RNA) II (DNA directed) polypeptide E, 25kDa pseudogene

MSANTD2P1 Gene

Myb/SANT-like DNA-binding domain containing 2 pseudogene 1

PRIMPOL Gene

primase and polymerase (DNA-directed)

TDP1 Gene

tyrosyl-DNA phosphodiesterase 1

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008]

LOC101060521 Gene

DNA-directed RNA polymerase III subunit RPC5

POLR3F Gene

polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa

The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

POLR3G Gene

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

POLR3D Gene

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa

This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, Jul 2008]

POLR3E Gene

polymerase (RNA) III (DNA directed) polypeptide E (80kD)

POLR3B Gene

polymerase (RNA) III (DNA directed) polypeptide B

This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

POLR3C Gene

polymerase (RNA) III (DNA directed) polypeptide C (62kD)

POLR3A Gene

polymerase (RNA) III (DNA directed) polypeptide A, 155kDa

The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response. [provided by RefSeq, Aug 2011]

POLR3K Gene

polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa

This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.[provided by RefSeq, Jul 2010]

POLR3H Gene

polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)

DNMT1 Gene

DNA (cytosine-5-)-methyltransferase 1

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

PRKDC Gene

protein kinase, DNA-activated, catalytic polypeptide

This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]

DSCC1 Gene

DNA replication and sister chromatid cohesion 1

CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]

LOC100130177 Gene

uracil-DNA glycosylase pseudogene

D6S2723E Gene

DNA segment on chromosome 6 (unique, pseudogene) 2723 expressed sequence

DCLRE1CP1 Gene

DNA cross-link repair 1C pseudogene 1

DNA2 Gene

DNA replication helicase/nuclease 2

This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

DNMT3AP1 Gene

DNA methyltransferase 3A pseudogene 1

DDB2 Gene

damage-specific DNA binding protein 2, 48kDa

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

LOC401002 Gene

single stranded DNA binding protein 3 pseudogene

LOC646674 Gene

single stranded DNA binding protein 4 pseudogene

LOC100996860 Gene

TAR DNA-binding protein 43 pseudogene

CDT1 Gene

chromatin licensing and DNA replication factor 1

The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]

POLD4 Gene

polymerase (DNA-directed), delta 4, accessory subunit

This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

HELB Gene

helicase (DNA) B

This gene encodes a DNA-dependent ATPase which catalyzes the unwinding of DNA necessary for DNA replication, repair, recombination, and transcription. This gene is thought to function specifically during the S phase entry of the cell cycle. [provided by RefSeq, Mar 2012]

ZBP1 Gene

Z-DNA binding protein 1

This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

POLE3 Gene

polymerase (DNA directed), epsilon 3, accessory subunit

POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]

AHDC1 Gene

AT hook, DNA binding motif, containing 1

This gene encodes a protein containing two AT-hooks, which likely function in DNA binding. Mutations in this gene were found in individuals with Xia-Gibbs syndrome. [provided by RefSeq, Jun 2014]

LPSA Gene

Oncogene liposarcoma (DNA segment, single copy, expressed, probes

RFX8 Gene

RFX family member 8, lacking RFX DNA binding domain

LOC643387 Gene

TAR DNA binding protein pseudogene

LOC246724 Gene

DNA directed RNA polymerase II polypeptide J-related gene

LOC246725 Gene

DNA directed RNA polymerase II polypeptide J-related gene

LOC101060644 Gene

TAR DNA-binding protein 43 pseudogene

LOC646804 Gene

alkylated DNA repair protein alkB homolog 8-like

POLR3KP2 Gene

polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa pseudogene 2

POLR3KP1 Gene

polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa pseudogene 1

POLDIP3 Gene

polymerase (DNA-directed), delta interacting protein 3

This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

POLDIP2 Gene

polymerase (DNA-directed), delta interacting protein 2

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

DFFA Gene

DNA fragmentation factor, 45kDa, alpha polypeptide

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

DFFB Gene

DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined. [provided by RefSeq, Sep 2013]

REV3L Gene

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

LOC101059974 Gene

p53 and DNA damage-regulated protein 1 pseudogene

MCIDAS Gene

multiciliate differentiation and DNA synthesis associated cell cycle protein

WDHD1 Gene

WD repeat and HMG-box DNA binding protein 1

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

LOC101930420 Gene

DNA primase large subunit-like

LIG4 Gene

ligase IV, DNA, ATP-dependent

The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

LIG1 Gene

ligase I, DNA, ATP-dependent

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

LIG3 Gene

ligase III, DNA, ATP-dependent

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

LOC100132723 Gene

single stranded DNA binding protein 4 pseudogene

LOC100129321 Gene

single stranded DNA binding protein 3 pseudogene

TDGP1 Gene

thymine-DNA glycosylase pseudogene 1

REV1 Gene

REV1, polymerase (DNA directed)

This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found. [provided by RefSeq, Jul 2008]

LOC100128540 Gene

TAR DNA-binding protein 43-like

ID2B Gene

inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)

RAD1 Gene

RAD1 checkpoint DNA exonuclease

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]

LOC101928945 Gene

uracil-DNA glycosylase pseudogene

PIF1 Gene

PIF1 5'-to-3' DNA helicase

This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus. [provided by RefSeq, Nov 2013]

POLR2KP1 Gene

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa pseudogene 1

TOP3BP1 Gene

topoisomerase (DNA) III beta pseudogene 1

This gene was predicted by automated computational analysis. It encodes a protein with similarity to human topoisomerase (DNA) III beta, which is thought to relax supercoiled DNA upon replication, transcription, and cell division. This gene lies in the immunoglobulin lambda gene cluster on chromosome 22q11.21. [provided by RefSeq, Jul 2008]

MSANTD4 Gene

Myb/SANT-like DNA-binding domain containing 4 with coiled-coils

MSANTD1 Gene

Myb/SANT-like DNA-binding domain containing 1

MSANTD2 Gene

Myb/SANT-like DNA-binding domain containing 2

MSANTD3 Gene

Myb/SANT-like DNA-binding domain containing 3

TARDBP Gene

TAR DNA binding protein

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]

BKMA1 Gene

Banded krait minor satellite DNA-1

POLG Gene

polymerase (DNA directed), gamma

Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

POLE Gene

polymerase (DNA directed), epsilon, catalytic subunit

This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013]

POLB Gene

polymerase (DNA directed), beta

The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011]

POLM Gene

polymerase (DNA directed), mu

POLL Gene

polymerase (DNA directed), lambda

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]

POLK Gene

polymerase (DNA directed) kappa

External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010]

POLI Gene

polymerase (DNA directed) iota

POLH Gene

polymerase (DNA directed), eta

This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

LOC100420848 Gene

Myb/SANT-like DNA-binding domain containing 3 pseudogene

POLE2 Gene

polymerase (DNA directed), epsilon 2, accessory subunit

POLE4 Gene

polymerase (DNA-directed), epsilon 4, accessory subunit

POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]

TOP2B Gene

topoisomerase (DNA) II beta 180kDa

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants; however, the second variant has not yet been fully described. [provided by RefSeq, Jul 2008]

TOP2A Gene

topoisomerase (DNA) II alpha 170kDa

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010]

GADD45GIP1 Gene

growth arrest and DNA-damage-inducible, gamma interacting protein 1

This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators. [provided by RefSeq, Aug 2012]

DCLRE1B Gene

DNA cross-link repair 1B

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008]

DCLRE1C Gene

DNA cross-link repair 1C

This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

DCLRE1A Gene

DNA cross-link repair 1A

This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

DFFBP1 Gene

DNA fragmentation factor, 40kDa, beta polypeptide pseudogene 1

HFM1 Gene

HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)

The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014]

KLLN Gene

killin, p53-regulated DNA replication inhibitor

The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012]

CHD1L Gene

chromodomain helicase DNA binding protein 1-like

This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012]

CHD1 Gene

chromodomain helicase DNA binding protein 1

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]

CHD3 Gene

chromodomain helicase DNA binding protein 3

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

CHD2 Gene

chromodomain helicase DNA binding protein 2

The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

CHD5 Gene

chromodomain helicase DNA binding protein 5

This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma. [provided by RefSeq, Feb 2012]

CHD4 Gene

chromodomain helicase DNA binding protein 4

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

CHD7 Gene

chromodomain helicase DNA binding protein 7

This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. [provided by RefSeq, Jul 2008]

CHD6 Gene

chromodomain helicase DNA binding protein 6

This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]

CHD9 Gene

chromodomain helicase DNA binding protein 9

CHD8 Gene

chromodomain helicase DNA binding protein 8

This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

CENPBD1P1 Gene

CENPB DNA-binding domains containing 1 pseudogene 1

MPG Gene

N-methylpurine-DNA glycosylase

POLRMT Gene

polymerase (RNA) mitochondrial (DNA directed)

This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008]

LOC727709 Gene

DNA-damage regulated autophagy modulator 1 pseudogene

MGMT Gene

O-6-methylguanine-DNA methyltransferase

GMNN Gene

geminin, DNA replication inhibitor

This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]

POLQ Gene

polymerase (DNA directed), theta

GADD45AP1 Gene

growth arrest and DNA-damage-inducible, alpha pseudogene 1

POLR3GL Gene

polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like

LOC100132659 Gene

single-stranded DNA binding protein 2 pseudogene

POLR2LP Gene

polymerase (RNA) II (DNA directed) polypeptide L pseudogene

DRAM1 Gene

DNA-damage regulated autophagy modulator 1

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]

DRAM2 Gene

DNA-damage regulated autophagy modulator 2

APEX1 Gene

APEX nuclease (multifunctional DNA repair enzyme) 1

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]

OGG1 Gene

8-oxoguanine DNA glycosylase

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]

TOP1P1 Gene

topoisomerase (DNA) I pseudogene 1

TOP1P2 Gene

topoisomerase (DNA) I pseudogene 2

SPIDR Gene

scaffolding protein involved in DNA repair

PDRG1 Gene

p53 and DNA-damage regulated 1

DMAP1 Gene

DNA methyltransferase 1 associated protein 1

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

SON Gene

SON DNA binding protein

This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

DDIT4L Gene

DNA-damage-inducible transcript 4-like

LOC100419572 Gene

uracil-DNA glycosylase pseudogene

LOC100133127 Gene

geminin, DNA replication inhibitor pseudogene 1

DDB1 Gene

damage-specific DNA binding protein 1, 127kDa

The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012]

POLA2 Gene

polymerase (DNA directed), alpha 2, accessory subunit

POLA1 Gene

polymerase (DNA directed), alpha 1, catalytic subunit

This gene encodes the catalytic subunit of DNA polymerase, which together with a regulatory and two primase subunits, forms the DNA polymerase alpha complex. The catalytic subunit plays an essential role in the initiation of DNA replication. [provided by RefSeq, Mar 2010]

POLR2KP2 Gene

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa pseudogene 2

MMS22L Gene

MMS22-like, DNA repair protein

POLR3DP1 Gene

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa pseudogene 1

TOP1MT Gene

topoisomerase (DNA) I, mitochondrial

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

DNMT3B Gene

DNA (cytosine-5-)-methyltransferase 3 beta

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]

DNMT3A Gene

DNA (cytosine-5-)-methyltransferase 3 alpha

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

DNMT3L Gene

DNA (cytosine-5-)-methyltransferase 3-like

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

LOC105373057 Gene

DNA-directed RNA polymerase II subunit RPB1-like

LOC642897 Gene

N-6 adenine-specific DNA methyltransferase 1 (putative) pseudogene

UNG Gene

uracil-DNA glycosylase

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]

KIN Gene

Kin17 DNA and RNA binding protein

The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

POLR2J4 Gene

polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene

POLR2J2 Gene

polymerase (RNA) II (DNA directed) polypeptide J2

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008]

POLR2J3 Gene

polymerase (RNA) II (DNA directed) polypeptide J3

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008]

POLD2P1 Gene

polymerase (DNA directed), delta 2, accessory subunit pseudogene 1

POLR2E Gene

polymerase (RNA) II (DNA directed) polypeptide E, 25kDa

This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. [provided by RefSeq, Jul 2008]

POLR2D Gene

polymerase (RNA) II (DNA directed) polypeptide D

This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq, Jul 2008]

POLR2G Gene

polymerase (RNA) II (DNA directed) polypeptide G

This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq, Jan 2009]

POLR2F Gene

polymerase (RNA) II (DNA directed) polypeptide F

This gene encodes the sixth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit, in combination with at least two other subunits, forms a structure that stabilizes the transcribing polymerase on the DNA template. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

POLR2A Gene

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

POLR2C Gene

polymerase (RNA) II (DNA directed) polypeptide C, 33kDa

This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]

POLR2B Gene

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

POLR2M Gene

polymerase (RNA) II (DNA directed) polypeptide M

This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4. Readthrough transcription between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein) is represented with GeneID 145781. [provided by RefSeq, Oct 2013]

POLR2L Gene

polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]

POLR2I Gene

polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008]

POLR2H Gene

polymerase (RNA) II (DNA directed) polypeptide H

The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

POLR2K Gene

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]

POLR2J Gene

polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13. [provided by RefSeq, Jul 2008]

LOC196469 Gene

DNA dC->dU-editing enzyme APOBEC-3G-like

TOP3A Gene

topoisomerase (DNA) III alpha

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq, Jul 2008]

TOP3B Gene

topoisomerase (DNA) III beta

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013]

DMC1 Gene

DNA meiotic recombinase 1

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

SSBP1 Gene

single-stranded DNA binding protein 1, mitochondrial

SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]

SSBP3 Gene

single stranded DNA binding protein 3

SSBP2 Gene

single-stranded DNA binding protein 2

SSBP2 is a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]

LOC100422453 Gene

polymerase (DNA directed), delta 1, catalytic subunit 125kDa pseudogene

TOPBP1 Gene

topoisomerase (DNA) II binding protein 1

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]

POLD1 Gene

polymerase (DNA directed), delta 1, catalytic subunit

This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]

POLD2 Gene

polymerase (DNA directed), delta 2, accessory subunit

This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]

POLD3 Gene

polymerase (DNA-directed), delta 3, accessory subunit

This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]

ID4 Gene

inhibitor of DNA binding 4, dominant negative helix-loop-helix protein

This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner. [provided by RefSeq, Dec 2011]

ID2 Gene

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]

ID3 Gene

inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011]

ID1 Gene

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

LOC400174 Gene

single stranded DNA binding protein 4 pseudogene

GCFC2 Gene

GC-rich sequence DNA-binding factor 2

The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008]

LOC100420880 Gene

primase, DNA, polypeptide 1 (49kDa) pseudogene

POLRMTP1 Gene

polymerase (RNA) mitochondrial (DNA directed) pseudogene 1

LOC100133137 Gene

geminin, DNA replication inhibitor pseudogene 2

DDIAS Gene

DNA damage-induced apoptosis suppressor

TOP1 Gene

topoisomerase (DNA) I

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]

PRIM2B Gene

primase, DNA, polypeptide 2 (58kDa) pseudogene

TONSL Gene

tonsoku-like, DNA repair protein

The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. [provided by RefSeq, Jul 2008]

LOC100421824 Gene

polymerase (DNA directed), epsilon 2, accessory subunit pseudogene

UNGP1 Gene

uracil-DNA glycosylase pseudogene 1

UNGP3 Gene

uracil-DNA glycosylase pseudogene 3

UNGP2 Gene

uracil-DNA glycosylase pseudogene 2

DNCM Gene

DNA associated with cytoplasmic membrane

LOC100130321 Gene

DNA fragmentation factor, 45kDa, alpha polypeptide pseudogene

POLG2 Gene

polymerase (DNA directed), gamma 2, accessory subunit

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009]

MDC1 Gene

mediator of DNA-damage checkpoint 1

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]

PANDAR Gene

promoter of CDKN1A antisense DNA damage activated RNA

abnormal double-strand dna break repair Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal double-strand dna break repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

dna double-strand break processing involved in repair via single-strand annealing Gene Set

From GO Biological Process Annotations

genes participating in the dna double-strand break processing involved in repair via single-strand annealing biological process from the curated GO Biological Process Annotations dataset.

double-strand break repair via break-induced replication Gene Set

From GO Biological Process Annotations

genes participating in the double-strand break repair via break-induced replication biological process from the curated GO Biological Process Annotations dataset.

DNA double-strand break repair and VJ recombination XRCC4, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA double-strand break repair and VJ recombination XRCC4, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

negative regulation of double-strand break repair via homologous recombination Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of double-strand break repair via homologous recombination biological process from the curated GO Biological Process Annotations dataset.

double-strand break repair via nonhomologous end joining Gene Set

From GO Biological Process Annotations

genes participating in the double-strand break repair via nonhomologous end joining biological process from the curated GO Biological Process Annotations dataset.

double-strand break repair via homologous recombination Gene Set

From GO Biological Process Annotations

genes participating in the double-strand break repair via homologous recombination biological process from the curated GO Biological Process Annotations dataset.

negative regulation of double-strand break repair via nonhomologous end joining Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of double-strand break repair via nonhomologous end joining biological process from the curated GO Biological Process Annotations dataset.

regulation of double-strand break repair via nonhomologous end joining Gene Set

From GO Biological Process Annotations

genes participating in the regulation of double-strand break repair via nonhomologous end joining biological process from the curated GO Biological Process Annotations dataset.

negative regulation of double-strand break repair Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of double-strand break repair biological process from the curated GO Biological Process Annotations dataset.

double-strand break repair via alternative nonhomologous end joining Gene Set

From GO Biological Process Annotations

genes participating in the double-strand break repair via alternative nonhomologous end joining biological process from the curated GO Biological Process Annotations dataset.

regulation of double-strand break repair Gene Set

From GO Biological Process Annotations

genes participating in the regulation of double-strand break repair biological process from the curated GO Biological Process Annotations dataset.

positive regulation of double-strand break repair Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of double-strand break repair biological process from the curated GO Biological Process Annotations dataset.

positive regulation of double-strand break repair via nonhomologous end joining Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of double-strand break repair via nonhomologous end joining biological process from the curated GO Biological Process Annotations dataset.

double-strand break repair via classical nonhomologous end joining Gene Set

From GO Biological Process Annotations

genes participating in the double-strand break repair via classical nonhomologous end joining biological process from the curated GO Biological Process Annotations dataset.

double-strand break repair Gene Set

From GO Biological Process Annotations

genes participating in the double-strand break repair biological process from the curated GO Biological Process Annotations dataset.

regulation of double-strand break repair via homologous recombination Gene Set

From GO Biological Process Annotations

genes participating in the regulation of double-strand break repair via homologous recombination biological process from the curated GO Biological Process Annotations dataset.

Double-Strand Break Repair Gene Set

From Reactome Pathways

proteins participating in the Double-Strand Break Repair pathway from the Reactome Pathways dataset.

abnormal single-strand dna break repair Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal single-strand dna break repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

DNA double-strand break end-joining complex Gene Set

From CORUM Protein Complexes

proteins in the DNA double-strand break end-joining complex protein complex from the CORUM Protein Complexes dataset.

dna double-strand break processing Gene Set

From GO Biological Process Annotations

genes participating in the dna double-strand break processing biological process from the curated GO Biological Process Annotations dataset.

meiotic dna double-strand break formation Gene Set

From GO Biological Process Annotations

genes participating in the meiotic dna double-strand break formation biological process from the curated GO Biological Process Annotations dataset.

Processing of DNA double-strand break ends Gene Set

From Reactome Pathways

proteins participating in the Processing of DNA double-strand break ends pathway from the Reactome Pathways dataset.

ATM mediated response to DNA double-strand break Gene Set

From Reactome Pathways

proteins participating in the ATM mediated response to DNA double-strand break pathway from the Reactome Pathways dataset.

double-strand/single-strand dna junction binding Gene Set

From GO Molecular Function Annotations

genes performing the double-strand/single-strand dna junction binding molecular function from the curated GO Molecular Function Annotations dataset.

site of double-strand break Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the site of double-strand break cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

site of double-strand break Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the site of double-strand break cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

protein localization to site of double-strand break Gene Set

From GO Biological Process Annotations

genes participating in the protein localization to site of double-strand break biological process from the curated GO Biological Process Annotations dataset.

site of double-strand break Gene Set

From GO Cellular Component Annotations

proteins localized to the site of double-strand break cellular component from the curated GO Cellular Component Annotations dataset.

single strand break repair Gene Set

From GO Biological Process Annotations

genes participating in the single strand break repair biological process from the curated GO Biological Process Annotations dataset.

Double-strand recombination repair protein, Mei5-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Double-strand recombination repair protein, Mei5-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Recruitment of repair and signaling proteins to double-strand breaks Gene Set

From Reactome Pathways

proteins participating in the Recruitment of repair and signaling proteins to double-strand breaks pathway from the Reactome Pathways dataset.

Homologous recombination repair of replication-independent double-strand breaks Gene Set

From Reactome Pathways

proteins participating in the Homologous recombination repair of replication-independent double-strand breaks pathway from the Reactome Pathways dataset.

Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks Gene Set

From Reactome Pathways

proteins participating in the Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks pathway from the Reactome Pathways dataset.

Exosome-associated factor Rrp47/DNA strand repair C1D Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Exosome-associated factor Rrp47/DNA strand repair C1D protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Telomere C-strand (Lagging Strand) Synthesis Gene Set

From Reactome Pathways

proteins participating in the Telomere C-strand (Lagging Strand) Synthesis pathway from the Reactome Pathways dataset.

dna strand elongation involved in dna replication Gene Set

From GO Biological Process Annotations

genes participating in the dna strand elongation involved in dna replication biological process from the curated GO Biological Process Annotations dataset.

dna synthesis involved in dna repair Gene Set

From GO Biological Process Annotations

genes participating in the dna synthesis involved in dna repair biological process from the curated GO Biological Process Annotations dataset.

dna dealkylation involved in dna repair Gene Set

From GO Biological Process Annotations

genes participating in the dna dealkylation involved in dna repair biological process from the curated GO Biological Process Annotations dataset.

dna ligation involved in dna repair Gene Set

From GO Biological Process Annotations

genes participating in the dna ligation involved in dna repair biological process from the curated GO Biological Process Annotations dataset.

DNA helicase (DNA repair), Rad3 type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA helicase (DNA repair), Rad3 type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

pyrimidine dimer repair by nucleotide-excision repair Gene Set

From GO Biological Process Annotations

genes participating in the pyrimidine dimer repair by nucleotide-excision repair biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair involved in interstrand cross-link repair Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair involved in interstrand cross-link repair biological process from the curated GO Biological Process Annotations dataset.

abnormal dna repair Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal dna repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

dna strand breakage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna strand breakage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna strand renaturation Gene Set

From GO Biological Process Annotations

genes participating in the dna strand renaturation biological process from the curated GO Biological Process Annotations dataset.

regulation of dna strand elongation Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna strand elongation biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna strand elongation Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna strand elongation biological process from the curated GO Biological Process Annotations dataset.

dna strand elongation Gene Set

From GO Biological Process Annotations

genes participating in the dna strand elongation biological process from the curated GO Biological Process Annotations dataset.

single-strand selective uracil dna n-glycosylase activity Gene Set

From GO Molecular Function Annotations

genes performing the single-strand selective uracil dna n-glycosylase activity molecular function from the curated GO Molecular Function Annotations dataset.

Primosome PriB/single-strand DNA-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Primosome PriB/single-strand DNA-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Sequence-specific single-strand DNA-binding protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sequence-specific single-strand DNA-binding protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Minus-strand DNA synthesis Gene Set

From Reactome Pathways

proteins participating in the Minus-strand DNA synthesis pathway from the Reactome Pathways dataset.

Homologous DNA pairing and strand exchange Gene Set

From Reactome Pathways

proteins participating in the Homologous DNA pairing and strand exchange pathway from the Reactome Pathways dataset.

Presynaptic phase of homologous DNA pairing and strand exchange Gene Set

From Reactome Pathways

proteins participating in the Presynaptic phase of homologous DNA pairing and strand exchange pathway from the Reactome Pathways dataset.

Plus-strand DNA synthesis Gene Set

From Reactome Pathways

proteins participating in the Plus-strand DNA synthesis pathway from the Reactome Pathways dataset.

DNA strand elongation Gene Set

From Reactome Pathways

proteins participating in the DNA strand elongation pathway from the Reactome Pathways dataset.

regulation of single stranded viral rna replication via double stranded dna intermediate Gene Set

From GO Biological Process Annotations

genes participating in the regulation of single stranded viral rna replication via double stranded dna intermediate biological process from the curated GO Biological Process Annotations dataset.

single stranded viral rna replication via double stranded dna intermediate Gene Set

From GO Biological Process Annotations

genes participating in the single stranded viral rna replication via double stranded dna intermediate biological process from the curated GO Biological Process Annotations dataset.

positive regulation of single stranded viral rna replication via double stranded dna intermediate Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of single stranded viral rna replication via double stranded dna intermediate biological process from the curated GO Biological Process Annotations dataset.

negative regulation of single stranded viral rna replication via double stranded dna intermediate Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of single stranded viral rna replication via double stranded dna intermediate biological process from the curated GO Biological Process Annotations dataset.

double-stranded dna exodeoxyribonuclease activity Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded dna exodeoxyribonuclease activity molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded telomeric dna binding Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded telomeric dna binding molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded dna-dependent atpase activity Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded dna-dependent atpase activity molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded methylated dna binding Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded methylated dna binding molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded dna 5'-3' exodeoxyribonuclease activity Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded dna 5'-3' exodeoxyribonuclease activity molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded dna binding Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded dna binding molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded dna 3'-5' exodeoxyribonuclease activity Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded dna 3'-5' exodeoxyribonuclease activity molecular function from the curated GO Molecular Function Annotations dataset.

increased anti-double stranded dna antibody level Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the increased anti-double stranded dna antibody level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

decreased anti-double stranded dna antibody level Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the decreased anti-double stranded dna antibody level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

dna-breaks-double-stranded Gene Set

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term dna-breaks-double-stranded in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu protein domain from the InterPro Predicted Protein Domain Annotations dataset.

dna repair complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna repair complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna repair complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna repair complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

DNA repair complex NEIL2-PNK-Pol(beta)-LigIII(alpha)-XRCC1 Gene Set

From CORUM Protein Complexes

proteins in the DNA repair complex NEIL2-PNK-Pol(beta)-LigIII(alpha)-XRCC1 protein complex from the CORUM Protein Complexes dataset.

MSH2-MLH1-PMS2 DNA-repair initiation complex Gene Set

From CORUM Protein Complexes

proteins in the MSH2-MLH1-PMS2 DNA-repair initiation complex protein complex from the CORUM Protein Complexes dataset.

DNA repair complex NEIL1-PNK-Pol(beta)-LigIII(alpha)-XRCC1 Gene Set

From CORUM Protein Complexes

proteins in the DNA repair complex NEIL1-PNK-Pol(beta)-LigIII(alpha)-XRCC1 protein complex from the CORUM Protein Complexes dataset.

MSH2-MLH1-PMS2-PCNA DNA-repair initiation complex Gene Set

From CORUM Protein Complexes

proteins in the MSH2-MLH1-PMS2-PCNA DNA-repair initiation complex protein complex from the CORUM Protein Complexes dataset.

DNA Repair-Deficiency Disorders Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease DNA Repair-Deficiency Disorders from the curated CTD Gene-Disease Associations dataset.

NATURAL KILLER CELL AND GLUCOCORTICOID DEFICIENCY WITH DNA REPAIR DEFECT Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease NATURAL KILLER CELL AND GLUCOCORTICOID DEFICIENCY WITH DNA REPAIR DEFECT from the curated CTD Gene-Disease Associations dataset.

genomic instability; dna repair Gene Set

From GAD Gene-Disease Associations

genes associated with the disease genomic instability; dna repair in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna repair capacity Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna repair capacity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

nucleotide-excision repair, dna incision, 3'-to lesion Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, dna incision, 3'-to lesion biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair, dna incision Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, dna incision biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair, dna duplex unwinding Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, dna duplex unwinding biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair, dna incision, 5'-to lesion Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, dna incision, 5'-to lesion biological process from the curated GO Biological Process Annotations dataset.

base-excision repair, dna ligation Gene Set

From GO Biological Process Annotations

genes participating in the base-excision repair, dna ligation biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair, dna damage recognition Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, dna damage recognition biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna repair Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna repair biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna repair Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna repair biological process from the curated GO Biological Process Annotations dataset.

meiotic dna repair synthesis Gene Set

From GO Biological Process Annotations

genes participating in the meiotic dna repair synthesis biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair, dna gap filling Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, dna gap filling biological process from the curated GO Biological Process Annotations dataset.

dna repair Gene Set

From GO Biological Process Annotations

genes participating in the dna repair biological process from the curated GO Biological Process Annotations dataset.

mitochondrial dna repair Gene Set

From GO Biological Process Annotations

genes participating in the mitochondrial dna repair biological process from the curated GO Biological Process Annotations dataset.

regulation of dna repair Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna repair biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair, dna damage removal Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, dna damage removal biological process from the curated GO Biological Process Annotations dataset.

dna repair complex Gene Set

From GO Cellular Component Annotations

proteins localized to the dna repair complex cellular component from the curated GO Cellular Component Annotations dataset.

Lung Cancer (DNA repair capacity) Gene Set

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Lung Cancer (DNA repair capacity) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

abnormality of dna repair Gene Set

From GWASdb SNP-Phenotype Associations

genes associated with the abnormality of dna repair phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

defective dna repair after ultraviolet radiation damage Gene Set

From HPO Gene-Disease Associations

genes associated with the defective dna repair after ultraviolet radiation damage phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

abnormality of dna repair Gene Set

From HPO Gene-Disease Associations

genes associated with the abnormality of dna repair phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

DNA Repair-Deficiency Disorders Gene Set

From HuGE Navigator Gene-Phenotype Associations

genes associated with the DNA Repair-Deficiency Disorders phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

DNA repair protein Rad50, eukaryotes Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein Rad50, eukaryotes protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Helix-turn-helix, base-excision DNA repair, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Helix-turn-helix, base-excision DNA repair, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein MutS-homologue MSH6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS-homologue MSH6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-repair protein, UmuC-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-repair protein, UmuC-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein MutS, core Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS, core protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein MutS-like, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS-like, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein Mlh3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein Mlh3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alkylated DNA repair protein AlkB Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alkylated DNA repair protein AlkB protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA recombination and repair protein RecA-like, ATP-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA recombination and repair protein RecA-like, ATP-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein Mlh1/HexB Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein Mlh1/HexB protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alkylated DNA repair protein AlkB, homologue 8, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alkylated DNA repair protein AlkB, homologue 8, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein Pms1/Pms2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein Pms1/Pms2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein Mre11 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein Mre11 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair Rad51/transcription factor NusA, alpha-helical Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair Rad51/transcription factor NusA, alpha-helical protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein Rad4, subgroup Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein Rad4, subgroup protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein MutS, clamp Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS, clamp protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein rad10 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein rad10 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein Rad4 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein Rad4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair Nbs1, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair Nbs1, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein XRCC4 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein XRCC4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair metallo-beta-lactamase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair metallo-beta-lactamase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein, Swi5 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein, Swi5 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein MutS, connector domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS, connector domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein, Rev1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein, Rev1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-repair protein Xrcc1, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-repair protein Xrcc1, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein XRCC4, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein XRCC4, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-repair protein, UmuC-like, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-repair protein, UmuC-like, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein MutS, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA recombination and repair protein, RecA-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA recombination and repair protein, RecA-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA recombination and repair protein Rad51, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA recombination and repair protein Rad51, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA recombination and repair protein RecA, monomer-monomer interface Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA recombination and repair protein RecA, monomer-monomer interface protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein Rad52/59/22 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein Rad52/59/22 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA recombination/repair protein Rad51 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA recombination/repair protein Rad51 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA recombination/repair protein Rad52 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA recombination/repair protein Rad52 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair protein RadA Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair protein RadA protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Telomere-length maintenance and DNA damage repair Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Telomere-length maintenance and DNA damage repair protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair MutS Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair MutS protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair nuclease, XPF-type/Helicase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair nuclease, XPF-type/Helicase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein MutS, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA mismatch repair protein, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

natural killer cell and glucocorticoid deficiency with dna repair defect Gene Set

From OMIM Gene-Disease Associations

genes associated with the natural killer cell and glucocorticoid deficiency with dna repair defect phenotype from the curated OMIM Gene-Disease Associations dataset.

Gap-filling DNA repair synthesis and ligation in GG-NER Gene Set

From Reactome Pathways

proteins participating in the Gap-filling DNA repair synthesis and ligation in GG-NER pathway from the Reactome Pathways dataset.

Repair synthesis for gap-filling by DNA polymerase in TC-NER Gene Set

From Reactome Pathways

proteins participating in the Repair synthesis for gap-filling by DNA polymerase in TC-NER pathway from the Reactome Pathways dataset.

DNA Repair Gene Set

From Reactome Pathways

proteins participating in the DNA Repair pathway from the Reactome Pathways dataset.

Gap-filling DNA repair synthesis and ligation in TC-NER Gene Set

From Reactome Pathways

proteins participating in the Gap-filling DNA repair synthesis and ligation in TC-NER pathway from the Reactome Pathways dataset.

Repair synthesis of patch ~27-30 bases long by DNA polymerase Gene Set

From Reactome Pathways

proteins participating in the Repair synthesis of patch ~27-30 bases long by DNA polymerase pathway from the Reactome Pathways dataset.

abnormal double-negative t cell morphology Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal double-negative t cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

abnormal double-positive t cell morphology Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal double-positive t cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

break Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term break in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

abnormal mismatch repair Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal mismatch repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

abnormal base-excision repair Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal base-excision repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

strand Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term strand in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lagging strand elongation Gene Set

From GO Biological Process Annotations

genes participating in the lagging strand elongation biological process from the curated GO Biological Process Annotations dataset.

strand invasion Gene Set

From GO Biological Process Annotations

genes participating in the strand invasion biological process from the curated GO Biological Process Annotations dataset.

leading strand elongation Gene Set

From GO Biological Process Annotations

genes participating in the leading strand elongation biological process from the curated GO Biological Process Annotations dataset.

mitochondrial heavy strand promoter anti-sense binding Gene Set

From GO Molecular Function Annotations

genes performing the mitochondrial heavy strand promoter anti-sense binding molecular function from the curated GO Molecular Function Annotations dataset.

mitochondrial light strand promoter anti-sense binding Gene Set

From GO Molecular Function Annotations

genes performing the mitochondrial light strand promoter anti-sense binding molecular function from the curated GO Molecular Function Annotations dataset.

mitochondrial light strand promoter sense binding Gene Set

From GO Molecular Function Annotations

genes performing the mitochondrial light strand promoter sense binding molecular function from the curated GO Molecular Function Annotations dataset.

mitochondrial heavy strand promoter sense binding Gene Set

From GO Molecular Function Annotations

genes performing the mitochondrial heavy strand promoter sense binding molecular function from the curated GO Molecular Function Annotations dataset.

FANCD2 opposite strand protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the FANCD2 opposite strand protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Telomere C-strand synthesis initiation Gene Set

From Reactome Pathways

proteins participating in the Telomere C-strand synthesis initiation pathway from the Reactome Pathways dataset.

Processive synthesis on the lagging strand Gene Set

From Reactome Pathways

proteins participating in the Processive synthesis on the lagging strand pathway from the Reactome Pathways dataset.

Polymerase switching on the C-strand of the telomere Gene Set

From Reactome Pathways

proteins participating in the Polymerase switching on the C-strand of the telomere pathway from the Reactome Pathways dataset.

Removal of the Flap Intermediate from the C-strand Gene Set

From Reactome Pathways

proteins participating in the Removal of the Flap Intermediate from the C-strand pathway from the Reactome Pathways dataset.

Processive synthesis on the C-strand of the telomere Gene Set

From Reactome Pathways

proteins participating in the Processive synthesis on the C-strand of the telomere pathway from the Reactome Pathways dataset.

Lagging Strand Synthesis Gene Set

From Reactome Pathways

proteins participating in the Lagging Strand Synthesis pathway from the Reactome Pathways dataset.

Leading Strand Synthesis Gene Set

From Reactome Pathways

proteins participating in the Leading Strand Synthesis pathway from the Reactome Pathways dataset.

double stranded rna induced gene expression Gene Set

From Biocarta Pathways

proteins participating in the double stranded rna induced gene expression pathway from the Biocarta Pathways dataset.

Double outlet right ventricle Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Double outlet right ventricle phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Double Outlet Right Ventricle Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Double Outlet Right Ventricle from the curated CTD Gene-Disease Associations dataset.

double outlet right ventricle Gene Set

From DISEASES Text-mining Gene-Disease Assocation Evidence Scores

genes co-occuring with the disease double outlet right ventricle in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Double Oxidized Cysteine Gene Set

From DrugBank Drug Targets

interacting proteins for the Double Oxidized Cysteine drug from the curated DrugBank Drug Targets dataset.

double homozygosity for receptor polymorphisms of platelet gpia and gpiiia Gene Set

From GAD Gene-Disease Associations

genes associated with the disease double homozygosity for receptor polymorphisms of platelet gpia and gpiiia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

double outlet right ventricle; heart defects, congenital; pulmonary atresia; tetralogy of fallot; transposition of great vessels; truncus arteriosus, persistent Gene Set

From GAD Gene-Disease Associations

genes associated with the disease double outlet right ventricle; heart defects, congenital; pulmonary atresia; tetralogy of fallot; transposition of great vessels; truncus arteriosus, persistent in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

double Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term double in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

double-stranded rna-specific ribonuclease activity Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded rna-specific ribonuclease activity molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded rna binding Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded rna binding molecular function from the curated GO Molecular Function Annotations dataset.

double-stranded rna adenosine deaminase activity Gene Set

From GO Molecular Function Annotations

genes performing the double-stranded rna adenosine deaminase activity molecular function from the curated GO Molecular Function Annotations dataset.

double outlet right ventricle Gene Set

From HPO Gene-Disease Associations

genes associated with the double outlet right ventricle phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

double tooth Gene Set

From HPO Gene-Disease Associations

genes associated with the double tooth phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Zinc finger, double-stranded RNA binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Zinc finger, double-stranded RNA binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Double zinc ribbon Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Double zinc ribbon protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Double-stranded RNA-specific adenosine deaminase (DRADA) Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Double-stranded RNA-specific adenosine deaminase (DRADA) protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Double C2 protein, alpha/beta/gamma Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Double C2 protein, alpha/beta/gamma protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Double-stranded RNA-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Double-stranded RNA-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

double kidney pelvis Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double kidney pelvis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double inlet heart left ventricle Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double inlet heart left ventricle phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

decreased double-negative t cell number Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the decreased double-negative t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double aortic arch Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double aortic arch phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double outlet right ventricle Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double outlet right ventricle phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double ureter Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double ureter phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double outlet right ventricle, taussig bing type Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double outlet right ventricle, taussig bing type phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double outlet right ventricle with atrioventricular septal defect Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double outlet right ventricle with atrioventricular septal defect phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

decreased double-positive t cell number Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the decreased double-positive t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double outlet right ventricle, ventricular defect committed to aorta Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the double outlet right ventricle, ventricular defect committed to aorta phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

increased double-negative t cell number Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the increased double-negative t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

increased double-positive t cell number Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the increased double-positive t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

double-outlet right ventricle Gene Set

From OMIM Gene-Disease Associations

genes associated with the double-outlet right ventricle phenotype from the curated OMIM Gene-Disease Associations dataset.

dna-dependent protein kinase-dna ligase 4 complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna-dependent protein kinase-dna ligase 4 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

DNA ligase IV-Xrcc4-DNA-protein kinase complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-Xrcc4-DNA-protein kinase complex protein complex from the CORUM Protein Complexes dataset.

DNA ligase III-XRCC1-PNK-DNA-pol III multiprotein complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase III-XRCC1-PNK-DNA-pol III multiprotein complex protein complex from the CORUM Protein Complexes dataset.

dna-dependent dna replication Gene Set

From GO Biological Process Annotations

genes participating in the dna-dependent dna replication biological process from the curated GO Biological Process Annotations dataset.

dna damage response, detection of dna damage Gene Set

From GO Biological Process Annotations

genes participating in the dna damage response, detection of dna damage biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna-dependent dna replication initiation Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna-dependent dna replication initiation biological process from the curated GO Biological Process Annotations dataset.

regulation of dna-dependent dna replication initiation Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna-dependent dna replication initiation biological process from the curated GO Biological Process Annotations dataset.

regulation of dna-dependent dna replication Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna-dependent dna replication biological process from the curated GO Biological Process Annotations dataset.

dna ligation involved in dna recombination Gene Set

From GO Biological Process Annotations

genes participating in the dna ligation involved in dna recombination biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna-dependent dna replication Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna-dependent dna replication biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna-dependent dna replication Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna-dependent dna replication biological process from the curated GO Biological Process Annotations dataset.

dna-dependent dna replication maintenance of fidelity Gene Set

From GO Biological Process Annotations

genes participating in the dna-dependent dna replication maintenance of fidelity biological process from the curated GO Biological Process Annotations dataset.

dna unwinding involved in dna replication Gene Set

From GO Biological Process Annotations

genes participating in the dna unwinding involved in dna replication biological process from the curated GO Biological Process Annotations dataset.

dna-dependent protein kinase-dna ligase 4 complex Gene Set

From GO Cellular Component Annotations

proteins localized to the dna-dependent protein kinase-dna ligase 4 complex cellular component from the curated GO Cellular Component Annotations dataset.

single-stranded dna-dependent atp-dependent dna helicase activity Gene Set

From GO Molecular Function Annotations

genes performing the single-stranded dna-dependent atp-dependent dna helicase activity molecular function from the curated GO Molecular Function Annotations dataset.

dna-directed dna polymerase activity Gene Set

From GO Molecular Function Annotations

genes performing the dna-directed dna polymerase activity molecular function from the curated GO Molecular Function Annotations dataset.

DNA-directed DNA polymerase, family B, exonuclease domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA polymerase, family B, exonuclease domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA polymerase, family B, multifunctional domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA polymerase, family B, multifunctional domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA glycosylase/AP lyase, H2TH DNA-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA glycosylase/AP lyase, H2TH DNA-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA polymerase, family B, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA polymerase, family B, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA-polymerase, family A, mitochondria Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA-polymerase, family A, mitochondria protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Zinc finger, DNA-directed DNA polymerase, family B, alpha Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Zinc finger, DNA-directed DNA polymerase, family B, alpha protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA topoisomerase I, DNA binding, eukaryotic-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA topoisomerase I, DNA binding, eukaryotic-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA topoisomerase, type IA, DNA-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA topoisomerase, type IA, DNA-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA polymerase X Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA polymerase X protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA/RNA polymerase mu Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA/RNA polymerase mu protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA polymerase, family A, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA polymerase, family A, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA polymerase, family A, palm domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA polymerase, family A, palm domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA-directed DNA polymerase, family B Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA-directed DNA polymerase, family B protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Translesion synthesis by DNA polymerases bypassing lesion on DNA template Gene Set

From Reactome Pathways

proteins participating in the Translesion synthesis by DNA polymerases bypassing lesion on DNA template pathway from the Reactome Pathways dataset.

Integration of viral DNA into host genomic DNA Gene Set

From Reactome Pathways

proteins participating in the Integration of viral DNA into host genomic DNA pathway from the Reactome Pathways dataset.

mismatch repair complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mismatch repair complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

nucleotide-excision repair factor 1 complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the nucleotide-excision repair factor 1 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

nucleotide-excision repair complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the nucleotide-excision repair complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

nucleotide-excision repair factor 3 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nucleotide-excision repair factor 3 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

excinuclease repair complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the excinuclease repair complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nucleotide-excision repair factor 4 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nucleotide-excision repair factor 4 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

mismatch repair complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mismatch repair complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nucleotide-excision repair factor 2 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nucleotide-excision repair factor 2 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nucleotide-excision repair factor 1 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nucleotide-excision repair factor 1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nucleotide-excision repair complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nucleotide-excision repair complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nucleotide excision repair Gene Set

From GAD Gene-Disease Associations

genes associated with the disease nucleotide excision repair in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity Gene Set

From GAD Gene-Disease Associations

genes associated with the disease reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

repairinduced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairinduced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repaired Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repaired in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairresistant Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairresistant in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairreview Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairreview in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairrelated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairrelated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repaircompetent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repaircompetent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairdependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairdependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repair Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repair in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairxpd Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairxpd in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairindependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairindependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairdeficient Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairdeficient in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairregeneration Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairregeneration in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairproficient Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairproficient in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairrecombination Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairrecombination in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairs Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairs in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairtranscription Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairtranscription in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

repairing Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term repairing in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

photoreactive repair Gene Set

From GO Biological Process Annotations

genes participating in the photoreactive repair biological process from the curated GO Biological Process Annotations dataset.

meiotic mismatch repair Gene Set

From GO Biological Process Annotations

genes participating in the meiotic mismatch repair biological process from the curated GO Biological Process Annotations dataset.

protein repair Gene Set

From GO Biological Process Annotations

genes participating in the protein repair biological process from the curated GO Biological Process Annotations dataset.

pyrimidine dimer repair Gene Set

From GO Biological Process Annotations

genes participating in the pyrimidine dimer repair biological process from the curated GO Biological Process Annotations dataset.

transcription-coupled nucleotide-excision repair Gene Set

From GO Biological Process Annotations

genes participating in the transcription-coupled nucleotide-excision repair biological process from the curated GO Biological Process Annotations dataset.

regulation of mismatch repair Gene Set

From GO Biological Process Annotations

genes participating in the regulation of mismatch repair biological process from the curated GO Biological Process Annotations dataset.

rna repair Gene Set

From GO Biological Process Annotations

genes participating in the rna repair biological process from the curated GO Biological Process Annotations dataset.

base-excision repair, ap site formation Gene Set

From GO Biological Process Annotations

genes participating in the base-excision repair, ap site formation biological process from the curated GO Biological Process Annotations dataset.

base-excision repair, gap-filling Gene Set

From GO Biological Process Annotations

genes participating in the base-excision repair, gap-filling biological process from the curated GO Biological Process Annotations dataset.

mismatch repair Gene Set

From GO Biological Process Annotations

genes participating in the mismatch repair biological process from the curated GO Biological Process Annotations dataset.

regulation of nucleotide-excision repair Gene Set

From GO Biological Process Annotations

genes participating in the regulation of nucleotide-excision repair biological process from the curated GO Biological Process Annotations dataset.

postreplication repair Gene Set

From GO Biological Process Annotations

genes participating in the postreplication repair biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair, preincision complex assembly Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair, preincision complex assembly biological process from the curated GO Biological Process Annotations dataset.

recombinational repair Gene Set

From GO Biological Process Annotations

genes participating in the recombinational repair biological process from the curated GO Biological Process Annotations dataset.

base-excision repair Gene Set

From GO Biological Process Annotations

genes participating in the base-excision repair biological process from the curated GO Biological Process Annotations dataset.

non-recombinational repair Gene Set

From GO Biological Process Annotations

genes participating in the non-recombinational repair biological process from the curated GO Biological Process Annotations dataset.

plasma membrane repair Gene Set

From GO Biological Process Annotations

genes participating in the plasma membrane repair biological process from the curated GO Biological Process Annotations dataset.

positive regulation of mismatch repair Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of mismatch repair biological process from the curated GO Biological Process Annotations dataset.

nucleotide-excision repair Gene Set

From GO Biological Process Annotations

genes participating in the nucleotide-excision repair biological process from the curated GO Biological Process Annotations dataset.

interstrand cross-link repair Gene Set

From GO Biological Process Annotations

genes participating in the interstrand cross-link repair biological process from the curated GO Biological Process Annotations dataset.

uv-damage excision repair Gene Set

From GO Biological Process Annotations

genes participating in the uv-damage excision repair biological process from the curated GO Biological Process Annotations dataset.

mismatch repair complex Gene Set

From GO Cellular Component Annotations

proteins localized to the mismatch repair complex cellular component from the curated GO Cellular Component Annotations dataset.

nucleotide-excision repair factor 1 complex Gene Set

From GO Cellular Component Annotations

proteins localized to the nucleotide-excision repair factor 1 complex cellular component from the curated GO Cellular Component Annotations dataset.

nucleotide-excision repair complex Gene Set

From GO Cellular Component Annotations

proteins localized to the nucleotide-excision repair complex cellular component from the curated GO Cellular Component Annotations dataset.

mismatch repair complex binding Gene Set

From GO Molecular Function Annotations

genes performing the mismatch repair complex binding molecular function from the curated GO Molecular Function Annotations dataset.

NADH repair Gene Set

From HumanCyc Pathways

proteins participating in the NADH repair pathway from the HumanCyc Pathways dataset.

UV excision repair protein Rad23 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the UV excision repair protein Rad23 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

mismatch repair cancer syndrome Gene Set

From OMIM Gene-Disease Associations

genes associated with the mismatch repair cancer syndrome phenotype from the curated OMIM Gene-Disease Associations dataset.

repair Gene Set

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term repair in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Homologous Recombination Repair Gene Set

From Reactome Pathways

proteins participating in the Homologous Recombination Repair pathway from the Reactome Pathways dataset.

Nucleotide Excision Repair Gene Set

From Reactome Pathways

proteins participating in the Nucleotide Excision Repair pathway from the Reactome Pathways dataset.

Formation of transcription-coupled NER (TC-NER) repair complex Gene Set

From Reactome Pathways

proteins participating in the Formation of transcription-coupled NER (TC-NER) repair complex pathway from the Reactome Pathways dataset.

Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) Gene Set

From Reactome Pathways

proteins participating in the Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) pathway from the Reactome Pathways dataset.

Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Gene Set

From Reactome Pathways

proteins participating in the Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) pathway from the Reactome Pathways dataset.

Base-Excision Repair, AP Site Formation Gene Set

From Reactome Pathways

proteins participating in the Base-Excision Repair, AP Site Formation pathway from the Reactome Pathways dataset.

ATM mediated phosphorylation of repair proteins Gene Set

From Reactome Pathways

proteins participating in the ATM mediated phosphorylation of repair proteins pathway from the Reactome Pathways dataset.

Base Excision Repair Gene Set

From Reactome Pathways

proteins participating in the Base Excision Repair pathway from the Reactome Pathways dataset.

Mismatch Repair Gene Set

From Reactome Pathways

proteins participating in the Mismatch Repair pathway from the Reactome Pathways dataset.

Mismatch repair(Mus musculus) Gene Set

From Wikipathways Pathways

proteins participating in the Mismatch repair(Mus musculus) pathway from the Wikipathways Pathways dataset.

Mismatch repair(Homo sapiens) Gene Set

From Wikipathways Pathways

proteins participating in the Mismatch repair(Homo sapiens) pathway from the Wikipathways Pathways dataset.

abnormal dna replication Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal dna replication phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

abnormal dna methylation Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal dna methylation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

abnormal dna methylation during gametogenesis Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal dna methylation during gametogenesis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

cdk regulation of dna replication Gene Set

From Biocarta Pathways

proteins participating in the cdk regulation of dna replication pathway from the Biocarta Pathways dataset.

cdc25 and chk1 regulatory pathway in response to dna damage Gene Set

From Biocarta Pathways

proteins participating in the cdc25 and chk1 regulatory pathway in response to dna damage pathway from the Biocarta Pathways dataset.

apoptotic dna-fragmentation and tissue homeostasis Gene Set

From Biocarta Pathways

proteins participating in the apoptotic dna-fragmentation and tissue homeostasis pathway from the Biocarta Pathways dataset.

apoptotic signaling in response to dna damage Gene Set

From Biocarta Pathways

proteins participating in the apoptotic signaling in response to dna damage pathway from the Biocarta Pathways dataset.

rb tumor suppressor/checkpoint signaling in response to dna damage Gene Set

From Biocarta Pathways

proteins participating in the rb tumor suppressor/checkpoint signaling in response to dna damage pathway from the Biocarta Pathways dataset.

cadmium induces dna synthesis and proliferation in macrophages Gene Set

From Biocarta Pathways

proteins participating in the cadmium induces dna synthesis and proliferation in macrophages pathway from the Biocarta Pathways dataset.

mechanisms of transcriptional repression by dna methylation Gene Set

From Biocarta Pathways

proteins participating in the mechanisms of transcriptional repression by dna methylation pathway from the Biocarta Pathways dataset.

Mitochondrial DNA depletion syndrome 9 (encephalomyopathic with methylmalonic aciduria) Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 9 (encephalomyopathic with methylmalonic aciduria) phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA depletion syndrome 4B, MNGIE type Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 4B, MNGIE type phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA depletion syndrome 2 Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 2 phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Infertility associated with multi-tailed spermatozoa and excessive DNA Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Infertility associated with multi-tailed spermatozoa and excessive DNA phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA depletion syndrome 12 (cardiomyopathic type) Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 12 (cardiomyopathic type) phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA depletion syndrome 5 (encephalomyopathic with or without methylmalonic aciduria) Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 5 (encephalomyopathic with or without methylmalonic aciduria) phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA depletion syndrome 11 Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 11 phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA depletion syndrome 13 (encephalomyopathic type) Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 13 (encephalomyopathic type) phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA-depletion syndrome 3, hepatocerebral Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA-depletion syndrome 3, hepatocerebral phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Mitochondrial DNA depletion syndrome 7 (hepatocerebral type) Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Mitochondrial DNA depletion syndrome 7 (hepatocerebral type) phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 1 Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 1 phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 3 Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 3 phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

dna topoisomerase complex (atp-hydrolyzing) Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna topoisomerase complex (atp-hydrolyzing) cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna ligase iv complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna ligase iv complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

alpha dna polymerase:primase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the alpha dna polymerase:primase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna packaging complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna packaging complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna recombinase mediator complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna recombinase mediator complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna-directed rna polymerase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna-directed rna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna helicase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna helicase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna-directed rna polymerase ii, core complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna-directed rna polymerase ii, core complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

gamma dna polymerase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the gamma dna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna replication factor a complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna replication factor a complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

delta dna polymerase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the delta dna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

protein-dna complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the protein-dna complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

epsilon dna polymerase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the epsilon dna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna polymerase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna-directed rna polymerase i complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna-directed rna polymerase i complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna replication factor c complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna replication factor c complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna polymerase processivity factor complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna polymerase processivity factor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

zeta dna polymerase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the zeta dna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

nuclear dna-directed rna polymerase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the nuclear dna-directed rna polymerase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna-directed rna polymerase iii complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna-directed rna polymerase iii complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna-directed rna polymerase ii, holoenzyme Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna-directed rna polymerase ii, holoenzyme cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna bending complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna bending complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna polymerase iii complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna polymerase iii complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna-directed rna polymerase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna-directed rna polymerase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna ligase iv complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna ligase iv complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

alpha dna polymerase:primase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the alpha dna polymerase:primase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna viral genome Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna viral genome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna packaging complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna packaging complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna recombinase mediator complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna recombinase mediator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna helicase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna helicase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

gamma dna polymerase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the gamma dna polymerase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna replication factor a complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna replication factor a complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

extrachromosomal circular dna Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the extrachromosomal circular dna cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

protein-dna complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the protein-dna complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

epsilon dna polymerase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the epsilon dna polymerase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna-dependent protein kinase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna-dependent protein kinase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna replication preinitiation complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna replication preinitiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna polymerase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna polymerase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna polymerase iii complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna polymerase iii complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

protein-dna-rna complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the protein-dna-rna complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna replication termination region Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna replication termination region cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna replication factor c complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna replication factor c complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna polymerase processivity factor complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna polymerase processivity factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna ligase iii-xrcc1 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna ligase iii-xrcc1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna-directed rna polymerase v complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna-directed rna polymerase v complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nuclear dna-directed rna polymerase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nuclear dna-directed rna polymerase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

extrachromosomal dna Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the extrachromosomal dna cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna-directed rna polymerase ii, holoenzyme Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna-directed rna polymerase ii, holoenzyme cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

dna bending complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna bending complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

PTIP-DNA damage response complex Gene Set

From CORUM Protein Complexes

proteins in the PTIP-DNA damage response complex protein complex from the CORUM Protein Complexes dataset.

GammaH2AFX-NDHII-Ku70-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the GammaH2AFX-NDHII-Ku70-DNA complex protein complex from the CORUM Protein Complexes dataset.

PCNA-DNA polymerase delta complex Gene Set

From CORUM Protein Complexes

proteins in the PCNA-DNA polymerase delta complex protein complex from the CORUM Protein Complexes dataset.

DNA ligase IV-XRCC4-AHNK complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-XRCC4-AHNK complex protein complex from the CORUM Protein Complexes dataset.

DNA ligase IV-XRCC4 complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-XRCC4 complex protein complex from the CORUM Protein Complexes dataset.

PCNA-MutS-alpha-DNA initial complex Gene Set

From CORUM Protein Complexes

proteins in the PCNA-MutS-alpha-DNA initial complex protein complex from the CORUM Protein Complexes dataset.

BRCA1-BARD1-BACH1-DNA damage complex II Gene Set

From CORUM Protein Complexes

proteins in the BRCA1-BARD1-BACH1-DNA damage complex II protein complex from the CORUM Protein Complexes dataset.

OCT1-SOX2 DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the OCT1-SOX2 DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

CBF-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the CBF-DNA complex protein complex from the CORUM Protein Complexes dataset.

DNA polymerase delta complex Gene Set

From CORUM Protein Complexes

proteins in the DNA polymerase delta complex protein complex from the CORUM Protein Complexes dataset.

DNA polymerase alpha-primase complex Gene Set

From CORUM Protein Complexes

proteins in the DNA polymerase alpha-primase complex protein complex from the CORUM Protein Complexes dataset.

Bcl-xL-p53-PUMA complex, DNA damage induced Gene Set

From CORUM Protein Complexes

proteins in the Bcl-xL-p53-PUMA complex, DNA damage induced protein complex from the CORUM Protein Complexes dataset.

DNA synthesome complex (15 subunits) Gene Set

From CORUM Protein Complexes

proteins in the DNA synthesome complex (15 subunits) protein complex from the CORUM Protein Complexes dataset.

DNA polymerase alpha Gene Set

From CORUM Protein Complexes

proteins in the DNA polymerase alpha protein complex from the CORUM Protein Complexes dataset.

TEAD2-YAP DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the TEAD2-YAP DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

PAX6-SOX2 DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the PAX6-SOX2 DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

RUNX1-CBF-beta-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the RUNX1-CBF-beta-DNA complex protein complex from the CORUM Protein Complexes dataset.

NFAT-JUN-FOS DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the NFAT-JUN-FOS DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex Gene Set

From CORUM Protein Complexes

proteins in the 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex protein complex from the CORUM Protein Complexes dataset.

BRCA1-BARD1-BRCA2-DNA damage complex III Gene Set

From CORUM Protein Complexes

proteins in the BRCA1-BARD1-BRCA2-DNA damage complex III protein complex from the CORUM Protein Complexes dataset.

5S-DNA-TFIIIA-TFIIIC2 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the 5S-DNA-TFIIIA-TFIIIC2 subcomplex protein complex from the CORUM Protein Complexes dataset.

ERG-JUN-FOS DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the ERG-JUN-FOS DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

Rag1-Rag2 protein-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the Rag1-Rag2 protein-DNA complex protein complex from the CORUM Protein Complexes dataset.

DNA ligase IV-condensin complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-condensin complex protein complex from the CORUM Protein Complexes dataset.

DNA ligase IV-XRCC4-XLF complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-XRCC4-XLF complex protein complex from the CORUM Protein Complexes dataset.

DNA synthesome core complex Gene Set

From CORUM Protein Complexes

proteins in the DNA synthesome core complex protein complex from the CORUM Protein Complexes dataset.

TEAD1-YAP DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the TEAD1-YAP DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

DNA-PK-Ku complex Gene Set

From CORUM Protein Complexes

proteins in the DNA-PK-Ku complex protein complex from the CORUM Protein Complexes dataset.

TEAD4-YAP DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the TEAD4-YAP DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

Artemis-DNA-PK complex Gene Set

From CORUM Protein Complexes

proteins in the Artemis-DNA-PK complex protein complex from the CORUM Protein Complexes dataset.

AIF-CYPA-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the AIF-CYPA-DNA complex protein complex from the CORUM Protein Complexes dataset.

OCT1-OBF1-DNA-TLE1 complex Gene Set

From CORUM Protein Complexes

proteins in the OCT1-OBF1-DNA-TLE1 complex protein complex from the CORUM Protein Complexes dataset.

DNA synthesome complex (13 subunits) Gene Set

From CORUM Protein Complexes

proteins in the DNA synthesome complex (13 subunits) protein complex from the CORUM Protein Complexes dataset.

DNA-PK-Ku-eIF2-NF90-NF45 complex Gene Set

From CORUM Protein Complexes

proteins in the DNA-PK-Ku-eIF2-NF90-NF45 complex protein complex from the CORUM Protein Complexes dataset.

DNA-PK-Ku antigen complex Gene Set

From CORUM Protein Complexes

proteins in the DNA-PK-Ku antigen complex protein complex from the CORUM Protein Complexes dataset.

OCT4-SOX2 DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the OCT4-SOX2 DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

PCNA-MutS-alpha-MutL-alpha-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the PCNA-MutS-alpha-MutL-alpha-DNA complex protein complex from the CORUM Protein Complexes dataset.

DNA ligase IV-XRCC4 complex (LX complex) Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-XRCC4 complex (LX complex) protein complex from the CORUM Protein Complexes dataset.

DNA ligase IV-XRCC1 complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-XRCC1 complex protein complex from the CORUM Protein Complexes dataset.

TEAD3-YAP DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the TEAD3-YAP DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

BRCA1-BARD1-BACH1-DNA damage complex I Gene Set

From CORUM Protein Complexes

proteins in the BRCA1-BARD1-BACH1-DNA damage complex I protein complex from the CORUM Protein Complexes dataset.

Vigilin-DNA-PK-Ku antigen complex Gene Set

From CORUM Protein Complexes

proteins in the Vigilin-DNA-PK-Ku antigen complex protein complex from the CORUM Protein Complexes dataset.

SMAD3-SMAD4-CTCF protein-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the SMAD3-SMAD4-CTCF protein-DNA complex protein complex from the CORUM Protein Complexes dataset.

DHX9-ADAR-vigilin-DNA-PK-Ku antigen complex Gene Set

From CORUM Protein Complexes

proteins in the DHX9-ADAR-vigilin-DNA-PK-Ku antigen complex protein complex from the CORUM Protein Complexes dataset.

OCT1-OBF1-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the OCT1-OBF1-DNA complex protein complex from the CORUM Protein Complexes dataset.

NCOA6-DNA-PK-Ku-PARP1 complex Gene Set

From CORUM Protein Complexes

proteins in the NCOA6-DNA-PK-Ku-PARP1 complex protein complex from the CORUM Protein Complexes dataset.

DNA synthesome complex (17 subunits) Gene Set

From CORUM Protein Complexes

proteins in the DNA synthesome complex (17 subunits) protein complex from the CORUM Protein Complexes dataset.

p53-Bcl-xL complex, DNA-damage induced Gene Set

From CORUM Protein Complexes

proteins in the p53-Bcl-xL complex, DNA-damage induced protein complex from the CORUM Protein Complexes dataset.

PCNA-DNA ligase complex Gene Set

From CORUM Protein Complexes

proteins in the PCNA-DNA ligase complex protein complex from the CORUM Protein Complexes dataset.

DNA synthesome complex Gene Set

From CORUM Protein Complexes

proteins in the DNA synthesome complex protein complex from the CORUM Protein Complexes dataset.

DNA ligase III-XRCC1 complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase III-XRCC1 complex protein complex from the CORUM Protein Complexes dataset.

PUMA-Bcl-xL complex, DNA-damage induced Gene Set

From CORUM Protein Complexes

proteins in the PUMA-Bcl-xL complex, DNA-damage induced protein complex from the CORUM Protein Complexes dataset.

Stat1-alpha-dimer-CBP DNA-protein complex Gene Set

From CORUM Protein Complexes

proteins in the Stat1-alpha-dimer-CBP DNA-protein complex protein complex from the CORUM Protein Complexes dataset.

MGC1-DNA-PKcs-Ku complex Gene Set

From CORUM Protein Complexes

proteins in the MGC1-DNA-PKcs-Ku complex protein complex from the CORUM Protein Complexes dataset.

Rag1-Rag2-Ku70-Ku80 protein-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the Rag1-Rag2-Ku70-Ku80 protein-DNA complex protein complex from the CORUM Protein Complexes dataset.

p32-CBF-DNA complex Gene Set

From CORUM Protein Complexes

proteins in the p32-CBF-DNA complex protein complex from the CORUM Protein Complexes dataset.

CBP-RARA-RXRA-DNA complex, ligand stimulated Gene Set

From CORUM Protein Complexes

proteins in the CBP-RARA-RXRA-DNA complex, ligand stimulated protein complex from the CORUM Protein Complexes dataset.

DNA ligase IV-XRCC4-PNK complex Gene Set

From CORUM Protein Complexes

proteins in the DNA ligase IV-XRCC4-PNK complex protein complex from the CORUM Protein Complexes dataset.

cisplatin-DNA adduct Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical cisplatin-DNA adduct from the curated CTD Gene-Chemical Interactions dataset.

benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA from the curated CTD Gene-Chemical Interactions dataset.

aflatoxin B1-DNA adduct Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical aflatoxin B1-DNA adduct from the curated CTD Gene-Chemical Interactions dataset.

DNA-(2-amino-3-methylimidazo(4,5-f)quinoline) adduct Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical DNA-(2-amino-3-methylimidazo(4,5-f)quinoline) adduct from the curated CTD Gene-Chemical Interactions dataset.

2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct from the curated CTD Gene-Chemical Interactions dataset.

7,12-dimethylbenz(a)anthracene-DNA adduct Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical 7,12-dimethylbenz(a)anthracene-DNA adduct from the curated CTD Gene-Chemical Interactions dataset.

polycyclic aromatic hydrocarbons-DNA adduct Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical polycyclic aromatic hydrocarbons-DNA adduct from the curated CTD Gene-Chemical Interactions dataset.

benzo(a)pyrene-DNA adduct Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical benzo(a)pyrene-DNA adduct from the curated CTD Gene-Chemical Interactions dataset.

Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Recessive Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Recessive from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 4A (ALPERS TYPE) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 4A (ALPERS TYPE) from the curated CTD Gene-Disease Associations dataset.

Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 3 Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 3 from the curated CTD Gene-Disease Associations dataset.

Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 4 Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 4 from the curated CTD Gene-Disease Associations dataset.

Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 2 Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 2 from the curated CTD Gene-Disease Associations dataset.

Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1 Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1 from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 8A (ENCEPHALOMYOPATHIC TYPE WITH RENAL TUBULOPATHY) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 8A (ENCEPHALOMYOPATHIC TYPE WITH RENAL TUBULOPATHY) from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 5 (ENCEPHALOMYOPATHIC WITH OR WITHOUT METHYLMALONIC ACIDURIA) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 5 (ENCEPHALOMYOPATHIC WITH OR WITHOUT METHYLMALONIC ACIDURIA) from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 9 (ENCEPHALOMYOPATHIC TYPE WITH METHYLMALONIC ACIDURIA) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 9 (ENCEPHALOMYOPATHIC TYPE WITH METHYLMALONIC ACIDURIA) from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 4B (MNGIE TYPE) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 4B (MNGIE TYPE) from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 1 (MNGIE TYPE) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 1 (MNGIE TYPE) from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 6 (HEPATOCEREBRAL TYPE) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 6 (HEPATOCEREBRAL TYPE) from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 7 (HEPATOCEREBRAL TYPE) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 7 (HEPATOCEREBRAL TYPE) from the curated CTD Gene-Disease Associations dataset.

Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant, 5 Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant, 5 from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 3 (HEPATOCEREBRAL TYPE) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 3 (HEPATOCEREBRAL TYPE) from the curated CTD Gene-Disease Associations dataset.

MITOCHONDRIAL DNA DEPLETION SYNDROME 2 (MYOPATHIC TYPE) Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MITOCHONDRIAL DNA DEPLETION SYNDROME 2 (MYOPATHIC TYPE) from the curated CTD Gene-Disease Associations dataset.

DNA Gene Set

From dbGAP Gene-Trait Associations

genes associated with the trait DNA in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

dna ligase iv deficiency Gene Set

From DISEASES Text-mining Gene-Disease Assocation Evidence Scores

genes co-occuring with the disease dna ligase iv deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

dna Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

colonic neoplasms; dna damage; microsatellite instability Gene Set

From GAD Gene-Disease Associations

genes associated with the disease colonic neoplasms; dna damage; microsatellite instability in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

hiv-rna and cellular hiv-dna levels Gene Set

From GAD Gene-Disease Associations

genes associated with the disease hiv-rna and cellular hiv-dna levels in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

colorectal neoplasms; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease colorectal neoplasms; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

crohn disease; crohn's disease; dna damage; genomic instability Gene Set

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; dna damage; genomic instability in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; head and neck neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; head and neck neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

cell transformation, neoplastic; dna damage; lung neoplasms; neoplasm of lung Gene Set

From GAD Gene-Disease Associations

genes associated with the disease cell transformation, neoplastic; dna damage; lung neoplasms; neoplasm of lung in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

polycyclic aromatic hydrocarbon-dna adducts Gene Set

From GAD Gene-Disease Associations

genes associated with the disease polycyclic aromatic hydrocarbon-dna adducts in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; ehlers-danlos syndrome; Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; ehlers-danlos syndrome; in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; infertility, male; varicocele Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; infertility, male; varicocele in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

aberrant promoter methylation of p16(ink4a) and o(6)-methylguanine-dna methyltransferase Gene Set

From GAD Gene-Disease Associations

genes associated with the disease aberrant promoter methylation of p16(ink4a) and o(6)-methylguanine-dna methyltransferase in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

breast neoplasms; chromosome breakage; dna damage; mammary neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease breast neoplasms; chromosome breakage; dna damage; mammary neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

breast neoplasms; dna damage; mammary neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease breast neoplasms; dna damage; mammary neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

cystic fibrosis; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease cystic fibrosis; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

choline deficiency; dna damage; folic acid deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease choline deficiency; dna damage; folic acid deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; helicobacter infections; precancerous conditions; stomach neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; helicobacter infections; precancerous conditions; stomach neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; glaucoma, open-angle; mitochondrial diseases Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; glaucoma, open-angle; mitochondrial diseases in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

angiomyolipoma; dna damage; kidney neoplasms; tuberous sclerosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease angiomyolipoma; dna damage; kidney neoplasms; tuberous sclerosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; infertility, male Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; infertility, male in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; leukemia, lymphocytic, chronic; leukemia, lymphocytic, chronic, b-cell Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; leukemia, lymphocytic, chronic; leukemia, lymphocytic, chronic, b-cell in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; myocardial infarction Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; myocardial infarction in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

chromosome breakage; dna damage; myelodysplastic syndromes Gene Set

From GAD Gene-Disease Associations

genes associated with the disease chromosome breakage; dna damage; myelodysplastic syndromes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

carcinoma, papillary; dna damage; neoplasms, radiation-induced; thyroid neoplasm; thyroid neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease carcinoma, papillary; dna damage; neoplasms, radiation-induced; thyroid neoplasm; thyroid neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

carcinoma, pancreatic ductal; dna damage; pancreatic neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease carcinoma, pancreatic ductal; dna damage; pancreatic neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; melanoma; skin neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; melanoma; skin neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage, oxidative Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage, oxidative in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; micronuclei, chromosome-defective Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; micronuclei, chromosome-defective in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

carcinoma; dna damage; nasopharyngeal neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease carcinoma; dna damage; nasopharyngeal neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; lung neoplasms; micronuclei, chromosome-defective; neoplasm of lung Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; lung neoplasms; micronuclei, chromosome-defective; neoplasm of lung in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; leukemia, lymphocytic, chronic, b-cell Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; leukemia, lymphocytic, chronic, b-cell in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

carcinoma, basal cell; carcinoma, squamous cell; dna damage; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma Gene Set

From GAD Gene-Disease Associations

genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; dna damage; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; lung neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; lung neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

birth weight; chromosome aberrations; chromosome abnormality; dna damage; tobacco use disorder Gene Set

From GAD Gene-Disease Associations

genes associated with the disease birth weight; chromosome aberrations; chromosome abnormality; dna damage; tobacco use disorder in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; neoplasms, glandular and epithelial; ovarian neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; neoplasms, glandular and epithelial; ovarian neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; embryo loss; hyperhomocysteinemia; recurrence Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; embryo loss; hyperhomocysteinemia; recurrence in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; neoplasms, second primary; precursor b-cell lymphoblastic leukemia-lymphoma; precursor t-cell lymphoblastic leukemia-lymphoma; recurrence Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; neoplasms, second primary; precursor b-cell lymphoblastic leukemia-lymphoma; precursor t-cell lymphoblastic leukemia-lymphoma; recurrence in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; melanoma Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; melanoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; neoplasms; skin diseases Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; neoplasms; skin diseases in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

breast neoplasms; dna damage; ovarian neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease breast neoplasms; dna damage; ovarian neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

chromosome aberrations; chromosome abnormality; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease chromosome aberrations; chromosome abnormality; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna virus infections; fatty liver; flaviviridae infections; hepatitis, viral, human Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna virus infections; fatty liver; flaviviridae infections; hepatitis, viral, human in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage associated with exposure to air pollution Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage associated with exposure to air pollution in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

chromosome aberrations; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease chromosome aberrations; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; endometriosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; endometriosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; macular degeneration Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; macular degeneration in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

breast neoplasms; dna damage; lung neoplasms; mammary neoplasms; neoplasm of lung ; skin neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease breast neoplasms; dna damage; lung neoplasms; mammary neoplasms; neoplasm of lung ; skin neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna degradation, necrotic Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna degradation, necrotic in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

1-hydroxypyrene, urinary; dna adducts, aromatic; mutagenicity, urinary Gene Set

From GAD Gene-Disease Associations

genes associated with the disease 1-hydroxypyrene, urinary; dna adducts, aromatic; mutagenicity, urinary in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

arteriosclerosis; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease arteriosclerosis; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

atrophy; dna damage; gastritis, atrophic; metaplasia; stomach neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease atrophy; dna damage; gastritis, atrophic; metaplasia; stomach neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; lung neoplasms; neoplasm of lung Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; lung neoplasms; neoplasm of lung in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; gastritis, atrophic; helicobacter infections; stomach neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; gastritis, atrophic; helicobacter infections; stomach neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

carotid artery diseases; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease carotid artery diseases; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

polycyclic aromatic hydrocarbon-dna adduct levels Gene Set

From GAD Gene-Disease Associations

genes associated with the disease polycyclic aromatic hydrocarbon-dna adduct levels in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

agricultural workers' diseases; dna damage; substance-related disorders Gene Set

From GAD Gene-Disease Associations

genes associated with the disease agricultural workers' diseases; dna damage; substance-related disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; precursor cell lymphoblastic leukemia-lymphoma Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; precursor cell lymphoblastic leukemia-lymphoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; kidney failure, chronic Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; kidney failure, chronic in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; radiation injuries Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; radiation injuries in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

cockayne syndrome; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease cockayne syndrome; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

cardiovascular diseases; diabetes mellitus; diabetes mellitus, type 2; diabetic angiopathies; dna damage Gene Set

From GAD Gene-Disease Associations

genes associated with the disease cardiovascular diseases; diabetes mellitus; diabetes mellitus, type 2; diabetic angiopathies; dna damage in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

atherosclerosis; dna damage; hypertension; kidney diseases Gene Set

From GAD Gene-Disease Associations

genes associated with the disease atherosclerosis; dna damage; hypertension; kidney diseases in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna oxidation Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna oxidation in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

bile duct neoplasms; cholangiocarcinoma; cholangitis, sclerosing; dna damage; Gene Set

From GAD Gene-Disease Associations

genes associated with the disease bile duct neoplasms; cholangiocarcinoma; cholangitis, sclerosing; dna damage; in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

chromosome aberrations; chromosome abnormality; dna damage; neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease chromosome aberrations; chromosome abnormality; dna damage; neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna adducts Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna adducts in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage; nasopharyngeal neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage; nasopharyngeal neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna replication error and shorter survival Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna replication error and shorter survival in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

adenocarcinoma; dna damage; pancreatic neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease adenocarcinoma; dna damage; pancreatic neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna damage, biomarkers of Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna damage, biomarkers of in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

carcinoma, hepatocellular; dna damage; liver neoplasms Gene Set

From GAD Gene-Disease Associations

genes associated with the disease carcinoma, hepatocellular; dna damage; liver neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

dna Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dna in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

signal transduction in response to dna damage Gene Set

From GO Biological Process Annotations

genes participating in the signal transduction in response to dna damage biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna-templated transcription, termination Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna-templated transcription, termination biological process from the curated GO Biological Process Annotations dataset.

dna integrity checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the dna integrity checkpoint biological process from the curated GO Biological Process Annotations dataset.

transcription, dna-templated Gene Set

From GO Biological Process Annotations

genes participating in the transcription, dna-templated biological process from the curated GO Biological Process Annotations dataset.

dna replication checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the dna replication checkpoint biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of sequence-specific dna binding transcription factor activity Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of sequence-specific dna binding transcription factor activity biological process from the curated GO Biological Process Annotations dataset.

dna rewinding Gene Set

From GO Biological Process Annotations

genes participating in the dna rewinding biological process from the curated GO Biological Process Annotations dataset.

signal transduction involved in dna damage checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the signal transduction involved in dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

pre-replicative complex assembly involved in cell cycle dna replication Gene Set

From GO Biological Process Annotations

genes participating in the pre-replicative complex assembly involved in cell cycle dna replication biological process from the curated GO Biological Process Annotations dataset.

dna damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations

genes participating in the dna damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations dataset.

regulation of dna damage checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

removal of rna primer involved in mitotic dna replication Gene Set

From GO Biological Process Annotations

genes participating in the removal of rna primer involved in mitotic dna replication biological process from the curated GO Biological Process Annotations dataset.

dna methylation on cytosine Gene Set

From GO Biological Process Annotations

genes participating in the dna methylation on cytosine biological process from the curated GO Biological Process Annotations dataset.

regulation of dna-templated transcription, initiation Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna-templated transcription, initiation biological process from the curated GO Biological Process Annotations dataset.

negative regulation of transcription regulatory region dna binding Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of transcription regulatory region dna binding biological process from the curated GO Biological Process Annotations dataset.

negative regulation of mitotic cell cycle dna replication Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of mitotic cell cycle dna replication biological process from the curated GO Biological Process Annotations dataset.

regulation of dna recombination Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna recombination biological process from the curated GO Biological Process Annotations dataset.

transcription-dependent tethering of rna polymerase ii gene dna at nuclear periphery Gene Set

From GO Biological Process Annotations

genes participating in the transcription-dependent tethering of rna polymerase ii gene dna at nuclear periphery biological process from the curated GO Biological Process Annotations dataset.

dna packaging Gene Set

From GO Biological Process Annotations

genes participating in the dna packaging biological process from the curated GO Biological Process Annotations dataset.

response to dna damage checkpoint signaling Gene Set

From GO Biological Process Annotations

genes participating in the response to dna damage checkpoint signaling biological process from the curated GO Biological Process Annotations dataset.

mitotic g2 dna damage checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the mitotic g2 dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

regulation of dna recombination at telomere Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna recombination at telomere biological process from the curated GO Biological Process Annotations dataset.

dna dealkylation Gene Set

From GO Biological Process Annotations

genes participating in the dna dealkylation biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna catabolic process Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna catabolic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna recombination Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna recombination biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna-templated transcription, initiation Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna-templated transcription, initiation biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

dna recombinase assembly Gene Set

From GO Biological Process Annotations

genes participating in the dna recombinase assembly biological process from the curated GO Biological Process Annotations dataset.

protein-dna complex assembly Gene Set

From GO Biological Process Annotations

genes participating in the protein-dna complex assembly biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna binding Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna binding biological process from the curated GO Biological Process Annotations dataset.

regulation of mitochondrial dna metabolic process Gene Set

From GO Biological Process Annotations

genes participating in the regulation of mitochondrial dna metabolic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna binding Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna binding biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations dataset.

dna conformation change Gene Set

From GO Biological Process Annotations

genes participating in the dna conformation change biological process from the curated GO Biological Process Annotations dataset.

signal transduction involved in dna integrity checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the signal transduction involved in dna integrity checkpoint biological process from the curated GO Biological Process Annotations dataset.

intra-s dna damage checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the intra-s dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

positive regulation of single-stranded telomeric dna binding Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of single-stranded telomeric dna binding biological process from the curated GO Biological Process Annotations dataset.

regulation of mitotic cell cycle dna replication Gene Set

From GO Biological Process Annotations

genes participating in the regulation of mitotic cell cycle dna replication biological process from the curated GO Biological Process Annotations dataset.

dna demethylation Gene Set

From GO Biological Process Annotations

genes participating in the dna demethylation biological process from the curated GO Biological Process Annotations dataset.

dna alkylation Gene Set

From GO Biological Process Annotations

genes participating in the dna alkylation biological process from the curated GO Biological Process Annotations dataset.

cellular response to dna damage stimulus Gene Set

From GO Biological Process Annotations

genes participating in the cellular response to dna damage stimulus biological process from the curated GO Biological Process Annotations dataset.

negative regulation of sequence-specific dna binding transcription factor activity Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of sequence-specific dna binding transcription factor activity biological process from the curated GO Biological Process Annotations dataset.

regulation of rna polymerase ii regulatory region sequence-specific dna binding Gene Set

From GO Biological Process Annotations

genes participating in the regulation of rna polymerase ii regulatory region sequence-specific dna binding biological process from the curated GO Biological Process Annotations dataset.

regulation of dna demethylation Gene Set

From GO Biological Process Annotations

genes participating in the regulation of dna demethylation biological process from the curated GO Biological Process Annotations dataset.

intracellular signal transduction involved in g1 dna damage checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the intracellular signal transduction involved in g1 dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

negative regulation of dna damage checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

dna duplex unwinding Gene Set

From GO Biological Process Annotations

genes participating in the dna duplex unwinding biological process from the curated GO Biological Process Annotations dataset.

rna-dependent dna replication Gene Set

From GO Biological Process Annotations

genes participating in the rna-dependent dna replication biological process from the curated GO Biological Process Annotations dataset.

negative regulation of rna polymerase ii regulatory region sequence-specific dna binding Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of rna polymerase ii regulatory region sequence-specific dna binding biological process from the curated GO Biological Process Annotations dataset.

signal transduction involved in mitotic dna damage checkpoint Gene Set

From GO Biological Process Annotations

genes participating in the signal transduction involved in mitotic dna damage checkpoint biological process from the curated GO Biological Process Annotations dataset.

dna cytosine deamination Gene Set

From GO Biological Process Annotations

genes participating in the dna cytosine deamination biological process from the curated GO Biological Process Annotations dataset.

dna damage induced protein phosphorylation Gene Set

From GO Biological Process Annotations

genes participating in the dna damage induced protein phosphorylation biological process from the curated GO Biological Process Annotations dataset.

dna catabolic process Gene Set

From GO Biological Process Annotations

genes participating in the dna catabolic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of dna endoreduplication Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of dna endoreduplication bi