Name

MSRA Gene

methionine sulfoxide reductase A

This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

MSRB1P1 Gene

methionine sulfoxide reductase B1 pseudogene 1

MSRB1 Gene

methionine sulfoxide reductase B1

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein family which includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this gene is expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol. [provided by RefSeq, Mar 2012]

MSRB3 Gene

methionine sulfoxide reductase B3

The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]

MSRB2 Gene

methionine sulfoxide reductase B2

MAT1A Gene

methionine adenosyltransferase I, alpha

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]

MAT2A Gene

methionine adenosyltransferase II, alpha

The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]

MAT2B Gene

methionine adenosyltransferase II, beta

The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

RSAD2 Gene

radical S-adenosyl methionine domain containing 2

RSAD1 Gene

radical S-adenosyl methionine domain containing 1

TRNAM-CAU Gene

transfer RNA methionine (anticodon CAU)

This record serves to anchor the annotations of this class of tRNAs at multiple locations on the human genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

LOC100653395 Gene

methionine adenosyltransferase II, alpha pseudogene

TRMEP1 Gene

tRNA methionine elongator pseudogene 1

AKR7A2 Gene

aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. [provided by RefSeq, Oct 2011]

AKR7A3 Gene

aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)

Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]

AKR1B1 Gene

aldo-keto reductase family 1, member B1 (aldose reductase)

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]

AKR1B10 Gene

aldo-keto reductase family 1, member B10 (aldose reductase)

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]

AKR1A1 Gene

aldo-keto reductase family 1, member A1 (aldehyde reductase)

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011]

LOC159007 Gene

aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) pseudogene

GRHPR Gene

glyoxylate reductase/hydroxypyruvate reductase

This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008]

SPPL3 Gene

signal peptide peptidase like 3

PYY Gene

peptide YY

The protein encoded by this gene is proteolytically processed to release a peptide that inhibits pancreatic secretion and mobility in the gut. Rare variations in this gene could increase susceptibility to obesity. [provided by RefSeq, Jul 2010]

PYY2 Gene

peptide YY, 2 (pseudogene)

PYY3 Gene

peptide YY, 3 (pseudogene)

QPCT Gene

glutaminyl-peptide cyclotransferase

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]

APEH Gene

acylaminoacyl-peptide hydrolase

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008]

QRFP Gene

pyroglutamylated RFamide peptide

The P518 precursor protein can be processed into several RF (arg-phe)-amide peptides, including P518. RF-amide peptides share a common C-terminal motif and are involved in cell signaling through G protein-coupled receptors (Jiang et al., 2003 [PubMed 12714592]).[supplied by OMIM, Mar 2008]

LOC100288484 Gene

formyl peptide receptor 1 pseudogene

SCUBE2 Gene

signal peptide, CUB domain, EGF-like 2

SCUBE3 Gene

signal peptide, CUB domain, EGF-like 3

This gene encodes a member of the signal peptide, complement subcomponents C1r/C1s, Uegf, bone morphogenetic protein-1 and epidermal growth factor-like domain containing protein family. Overexpression of this gene in human embryonic kidney cells results in secretion of a glycosylated form of the protein that forms oligomers and tethers to the cell surface. This gene is upregulated in lung cancer tumor tissue compared to healthy tissue and is associated with loss of the epithelial marker E-cadherin and with increased expression of vimentin, a mesenchymal marker. In addition, the protein encoded by this gene is a transforming growth factor beta receptor ligand, and when secreted by cancer cells, it can be cleaved in vitro to release the N-terminal epidermal growth factor-like repeat domain and the C-terminal complement subcomponents C1r/C1s domain. Both the full length protein and C-terminal fragment can bind to the transforming growth factor beta type II receptor to promote the epithelial-mesenchymal transition and tumor angiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

SCUBE1 Gene

signal peptide, CUB domain, EGF-like 1

This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]

LOC100132647 Gene

signal peptide peptidase like 3 pseudogene

HAMP Gene

hepcidin antimicrobial peptide

The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014]

NPPA Gene

natriuretic peptide A

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009]

VIPR2 Gene

vasoactive intestinal peptide receptor 2

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]

VIPR1 Gene

vasoactive intestinal peptide receptor 1

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

GALP Gene

galanin-like peptide

This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors.[provided by RefSeq, Nov 2014]

LOC390614 Gene

relaxin/insulin-like family peptide receptor 3 pseudogene

NPR2 Gene

natriuretic peptide receptor 2

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]

NPR3 Gene

natriuretic peptide receptor 3

This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

TPRX1 Gene

tetra-peptide repeat homeobox 1

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]

TPRXL Gene

tetra-peptide repeat homeobox-like

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]

GRPR Gene

gastrin-releasing peptide receptor

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]

SPPL2A Gene

signal peptide peptidase like 2A

This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012]

SPPL2C Gene

signal peptide peptidase like 2C

SPPL2B Gene

signal peptide peptidase like 2B

This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GRP Gene

gastrin-releasing peptide

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

QRFPR Gene

pyroglutamylated RFamide peptide receptor

QPCTL Gene

glutaminyl-peptide cyclotransferase-like

LOC100420615 Gene

signal peptide peptidase like 2A pseudogene

CAMP Gene

cathelicidin antimicrobial peptide

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

NPPB Gene

natriuretic peptide B

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

NPPC Gene

natriuretic peptide C

The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. [provided by RefSeq, Sep 2011]

RXFP1 Gene

relaxin/insulin-like family peptide receptor 1

This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

RXFP3 Gene

relaxin/insulin-like family peptide receptor 3

RXFP2 Gene

relaxin/insulin-like family peptide receptor 2

This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

RXFP4 Gene

relaxin/insulin-like family peptide receptor 4

GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]

NPR1 Gene

natriuretic peptide receptor 1

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009]

MEP1A Gene

meprin A, alpha (PABA peptide hydrolase)

FPR1 Gene

formyl peptide receptor 1

This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]

FPR2 Gene

formyl peptide receptor 2

FPR3 Gene

formyl peptide receptor 3

TPRX2P Gene

tetra-peptide repeat homeobox 2 pseudogene

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]

VIP Gene

vasoactive intestinal peptide

The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]

GLP2R Gene

glucagon-like peptide 2 receptor

This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]

NPFF Gene

neuropeptide FF-amide peptide precursor

FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two active peptides with similar function. [provided by RefSeq, Jul 2008]

TPRX1P1 Gene

tetra-peptide repeat homeobox 1 pseudogene 1

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]

LEAP2 Gene

liver expressed antimicrobial peptide 2

This gene encodes a cysteine-rich cationic antimicrobial peptide that is expressed predominantly in the liver. The mature peptide has activity against gram-positive bacteria and yeasts. [provided by RefSeq, Sep 2014]

PDF Gene

peptide deformylase (mitochondrial)

Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. [provided by RefSeq, Nov 2008]

GLP1R Gene

glucagon-like peptide 1 receptor

PECR Gene

peroxisomal trans-2-enoyl-CoA reductase

SRD5A3 Gene

steroid 5 alpha-reductase 3

The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]

SRD5A2 Gene

steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]

SRD5A1 Gene

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]

LOC100130018 Gene

prostaglandin reductase 1 pseudogene

SDR42E1 Gene

short chain dehydrogenase/reductase family 42E, member 1

CRYZL1 Gene

crystallin, zeta (quinone reductase)-like 1

This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]

DHRS11 Gene

dehydrogenase/reductase (SDR family) member 11

DHRS12 Gene

dehydrogenase/reductase (SDR family) member 12

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members in this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

DHRS13 Gene

dehydrogenase/reductase (SDR family) member 13

FAR2P1 Gene

fatty acyl CoA reductase 2 pseudogene 1

DCXR Gene

dicarbonyl/L-xylulose reductase

The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]

AKR7A2P1 Gene

aldo-keto reductase family 7, member A2 pseudogene 1

SDR42E2 Gene

short chain dehydrogenase/reductase family 42E, member 2

RRM2 Gene

ribonucleotide reductase M2

This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]

RRM1 Gene

ribonucleotide reductase M1

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]

KDSR Gene

3-ketodihydrosphingosine reductase

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008]

PTGR1 Gene

prostaglandin reductase 1

This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

PTGR2 Gene

prostaglandin reductase 2

This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

MGC34796 Gene

sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) pseudogene

LOC100418560 Gene

dihydrofolate reductase pseudogene

QDPR Gene

quinoid dihydropteridine reductase

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]

DHFRL1 Gene

dihydrofolate reductase-like 1

DHRS4L1 Gene

dehydrogenase/reductase (SDR family) member 4 like 1

DHRS4L2 Gene

dehydrogenase/reductase (SDR family) member 4 like 2

This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

AKR1B15 Gene

aldo-keto reductase family 1, member B15

FRRS1L Gene

ferric-chelate reductase 1-like

LOC644310 Gene

ubiquinol-cytochrome c reductase, complex III subunit X pseudogene

SRD5A1P1 Gene

steroid-5-alpha-reductase, alpha polypeptide 1 pseudogene 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha pseudogene)

LOC100418558 Gene

dihydrofolate reductase pseudogene

DHRS7B Gene

dehydrogenase/reductase (SDR family) member 7B

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

DHRS7C Gene

dehydrogenase/reductase (SDR family) member 7C

MECR Gene

mitochondrial trans-2-enoyl-CoA reductase

LOC100420205 Gene

ribonucleotide reductase M2 pseudogene

TECRL Gene

trans-2,3-enoyl-CoA reductase-like

LOC100132056 Gene

dihydrofolate reductase pseudogene

BLVRB Gene

biliverdin reductase B

The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]

BLVRA Gene

biliverdin reductase A

The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]

LOC728667 Gene

dehydrogenase/reductase (SDR family) member 2 pseudogene

FAR2P4 Gene

fatty acyl CoA reductase 2 pseudogene 4

UQCR10 Gene

ubiquinol-cytochrome c reductase, complex III subunit X

UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 2008]

UQCR11 Gene

ubiquinol-cytochrome c reductase, complex III subunit XI

This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]

MTRR Gene

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

UQCRQ Gene

ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa

This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]

UQCRH Gene

ubiquinol-cytochrome c reductase hinge protein

UQCRB Gene

ubiquinol-cytochrome c reductase binding protein

This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X. [provided by RefSeq, Dec 2011]

LOC100421569 Gene

glyoxylate reductase 1 homolog (Arabidopsis) pseudogene

UQCRC2P1 Gene

ubiquinol-cytochrome c reductase core protein II pseudogene 1

UQCRFS1P1 Gene

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 1

UQCRFS1P2 Gene

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 2

UQCRFS1P3 Gene

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 3

CBR4 Gene

carbonyl reductase 4

CBR1 Gene

carbonyl reductase 1

The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]

CBR3 Gene

carbonyl reductase 3

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]

SDR16C6P Gene

short chain dehydrogenase/reductase family 16C, member 6, pseudogene

FAR2P3 Gene

fatty acyl CoA reductase 2 pseudogene 3

FAR2P2 Gene

fatty acyl CoA reductase 2 pseudogene 2

LOC727947 Gene

ubiquinol-cytochrome c reductase binding protein pseudogene

DHRS9 Gene

dehydrogenase/reductase (SDR family) member 9

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

DHRS7 Gene

dehydrogenase/reductase (SDR family) member 7

Short-chain dehydrogenases/reductases (SDRs), such as DHRS7, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]

DHRS4 Gene

dehydrogenase/reductase (SDR family) member 4

DHRS2 Gene

dehydrogenase/reductase (SDR family) member 2

DHRS3 Gene

dehydrogenase/reductase (SDR family) member 3

Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]

DHRS1 Gene

dehydrogenase/reductase (SDR family) member 1

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

DHRSX Gene

dehydrogenase/reductase (SDR family) X-linked

VKORC1 Gene

vitamin K epoxide reductase complex, subunit 1

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

RRM2B Gene

ribonucleotide reductase M2 B (TP53 inducible)

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

AKR1B1P4 Gene

aldo-keto reductase family 1, member B1 pseudogene 4

AKR1B1P5 Gene

aldo-keto reductase family 1, member B1 pseudogene 5

AKR1B1P6 Gene

aldo-keto reductase family 1, member B1 pseudogene 6

AKR1B1P7 Gene

aldo-keto reductase family 1, member B1 pseudogene 7

AKR1B1P1 Gene

aldehyde reductase family 1, member B1 pseudogene 1

AKR1B1P2 Gene

aldo-keto reductase family 1, member B1 pseudogene 2

AKR1B1P3 Gene

aldo-keto reductase family 1, member B1 pseudogene 3

AKR1B1P8 Gene

aldo-keto reductase family 1, member B1 pseudogene 8

VKORC1L1 Gene

vitamin K epoxide reductase complex, subunit 1-like 1

AKR1C7P Gene

aldo-keto reductase family 1, member C7, pseudogene

RRM2P4 Gene

ribonucleotide reductase M2 polypeptide pseudogene 4

RRM2P3 Gene

ribonucleotide reductase M2 polypeptide pseudogene 3

RRM2P2 Gene

ribonucleotide reductase M2 polypeptide pseudogene 2

CYBRD1 Gene

cytochrome b reductase 1

This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]

LOC441241 Gene

vitamin K epoxide reductase complex, subunit 1-like 1 pseudogene

AKR1B10P1 Gene

aldo-keto reductase family 1, member B10 pseudogene 1

AKR1B10P2 Gene

aldo-keto reductase family 1, member B10 pseudogene 2

UQCRBP2 Gene

ubiquinol-cytochrome c reductase binding protein pseudogene 2

UQCRBP3 Gene

ubiquinol-cytochrome c reductase binding protein pseudogene 3

UQCRBP1 Gene

ubiquinol-cytochrome c reductase binding protein pseudogene 1

GMPR2 Gene

guanosine monophosphate reductase 2

LOC100422348 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

LOC100422346 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

LOC100422347 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

SPR Gene

sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]

TECRP1 Gene

trans-2,3-enoyl-CoA reductase pseudogene 1

TECRP2 Gene

trans-2,3-enoyl-CoA reductase pseudogene 2

MTHFR Gene

methylenetetrahydrofolate reductase (NAD(P)H)

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]

AKR1C8P Gene

aldo-keto reductase family 1, member C8, pseudogene

LOC100418573 Gene

dihydrofolate reductase-like 1 pseudogene

FRRS1 Gene

ferric-chelate reductase 1

Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]

FAR1P1 Gene

fatty acyl CoA reductase 1 pseudogene 1

SDR42E1P1 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene 1

CRYZP1 Gene

crystallin, zeta (quinone reductase) pseudogene 1

CRYZP2 Gene

crystallin, zeta (quinone reductase) pseudogene 2

LOC100420006 Gene

fatty acyl CoA reductase 2 pseudogene

UQCRHL Gene

ubiquinol-cytochrome c reductase hinge protein-like

This gene has characteristics of a pseudogene derived from the UQCRH gene. However, there is still an open reading frame that could produce a protein of the same or nearly the same size as that of the UQCRH gene, so this gene is being called protein-coding for now. [provided by RefSeq, Jul 2008]

AKR1C1 Gene

aldo-keto reductase family 1, member C1

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

UQCRHP3 Gene

ubiquinol-cytochrome c reductase hinge protein pseudogene 3

LOC100420653 Gene

guanosine monophosphate reductase pseudogene

DHFRP2 Gene

dihydrofolate reductase pseudogene 2

BCS1L Gene

BC1 (ubiquinol-cytochrome c reductase) synthesis-like

This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Five alternatively spliced transcripts encoding the same protein have been described. [provided by RefSeq, Mar 2012]

FDXR Gene

ferredoxin reductase

This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]

AKR1D1P1 Gene

aldo-keto reductase family 1, member D1 pseudogene 1

UQCRFS1 Gene

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

AKR1C4 Gene

aldo-keto reductase family 1, member C4

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

AKR1C2 Gene

aldo-keto reductase family 1, member C2

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

HMGCR Gene

3-hydroxy-3-methylglutaryl-CoA reductase

HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

AKR1C3 Gene

aldo-keto reductase family 1, member C3

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

LOC100420171 Gene

fatty acyl CoA reductase 2 pseudogene

LOC100420172 Gene

fatty acyl CoA reductase 2 pseudogene

LOC100420175 Gene

fatty acyl CoA reductase 2 pseudogene

NDUFS5P3 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 3

NDUFS5P2 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 2

NDUFS5P7 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 7

NDUFS5P5 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 5

NDUFS5P4 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 4

SDR9C7 Gene

short chain dehydrogenase/reductase family 9C, member 7

This gene encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities. [provided by RefSeq, Apr 2010]

GLYR1 Gene

glyoxylate reductase 1 homolog (Arabidopsis)

SQRDL Gene

sulfide quinone reductase-like (yeast)

The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]

AKR7L Gene

aldo-keto reductase family 7-like (gene/pseudogene)

This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a duplicated pseudogene, and it is therefore represented as such in this Gene record. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]

AKR1C5P Gene

aldo-keto reductase family 1, member C5, pseudogene

CYB5R4 Gene

cytochrome b5 reductase 4

NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5 reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 [PubMed 10611283]).[supplied by OMIM, Jan 2010]

CYB5R3 Gene

cytochrome b5 reductase 3

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]

CYB5R2 Gene

cytochrome b5 reductase 2

The protein encoded by this gene belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

CYB5R1 Gene

cytochrome b5 reductase 1

CYB5RL Gene

cytochrome b5 reductase-like

NDUFS5P1 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) pseudogene 1

UQCRC2 Gene

ubiquinol-cytochrome c reductase core protein II

UQCRC1 Gene

ubiquinol-cytochrome c reductase core protein I

RETSAT Gene

retinol saturase (all-trans-retinol 13,14-reductase)

TXNRD3NB Gene

thioredoxin reductase 3 neighbor

LOC100419293 Gene

carbonyl reductase 1 pseudogene

CRYZ Gene

crystallin, zeta (quinone reductase)

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

KAR Gene

Aromatic alpha-keto acid reductase

DHFRP1 Gene

dihydrofolate reductase pseudogene 1

NDUFS1 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

NDUFS2 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

NDUFS3 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

NDUFS4 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq, Jul 2008]

NDUFS5 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)

This gene is a member of the NADH dehydrogenase (ubiquinone) iron-sulfur protein family. The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 1, 4 and 17. [provided by RefSeq, May 2010]

NDUFS6 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)

This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]

NDUFS7 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions. [provided by RefSeq, Jul 2008]

NDUFS8 Gene

NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]

PYCR2 Gene

pyrroline-5-carboxylate reductase family, member 2

This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

PYCR1 Gene

pyrroline-5-carboxylate reductase 1

This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

PYCRL Gene

pyrroline-5-carboxylate reductase-like

DHCR24 Gene

24-dehydrocholesterol reductase

This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]

AKR1D1 Gene

aldo-keto reductase family 1, member D1

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]

FAR1 Gene

fatty acyl CoA reductase 1

The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015]

FAR2 Gene

fatty acyl CoA reductase 2

This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012]

UQCC1 Gene

ubiquinol-cytochrome c reductase complex assembly factor 1

This gene encodes a transmembrane protein that is structurally similar to the mouse basic fibroblast growth factor repressed ZIC-binding protein. In mouse this protein may be involved in fibroblast growth factor regulated growth control. In humans, polymorphisms in this gene are associated with variation in human height and osteoarthritis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

UQCC3 Gene

ubiquinol-cytochrome c reductase complex assembly factor 3

Complex III is a mitochondrial inner membrane protein complex that transfers electrons from ubiquinol to cytochrome c. This gene encodes a protein that functions in complex III assembly. Mutations in this gene result in Mitochondrial complex III deficiency, nuclear type 9. [provided by RefSeq, Dec 2014]

UQCC2 Gene

ubiquinol-cytochrome c reductase complex assembly factor 2

This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012]

LOC100418559 Gene

dihydrofolate reductase pseudogene

AKR1E2 Gene

aldo-keto reductase family 1, member E2

The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

AKR1C6P Gene

aldo-keto reductase family 1, member C6, pseudogene

LOC1720 Gene

dihydrofolate reductase pseudogene

LOC100422339 Gene

short chain dehydrogenase/reductase family 42E, member 1 pseudogene

GMPR Gene

guanosine monophosphate reductase

This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]

GSR Gene

glutathione reductase

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]

DHCR7 Gene

7-dehydrocholesterol reductase

This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009]

TXNRD2 Gene

thioredoxin reductase 2

This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013]

TXNRD3 Gene

thioredoxin reductase 3

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

TXNRD1 Gene

thioredoxin reductase 1

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]

SDR16C5 Gene

short chain dehydrogenase/reductase family 16C, member 5

RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).[supplied by OMIM, Mar 2008]

UQCRHP4 Gene

ubiquinol-cytochrome c reductase hinge protein pseudogene 4

UQCRHP1 Gene

ubiquinol-cytochrome c reductase hinge protein pseudogene 1

UQCRHP2 Gene

ubiquinol-cytochrome c reductase hinge protein pseudogene 2

DECR2 Gene

2,4-dienoyl CoA reductase 2, peroxisomal

DECR1 Gene

2,4-dienoyl CoA reductase 1, mitochondrial

This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]

DHFR Gene

dihydrofolate reductase

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]

SRD5A3P1 Gene

steroid 5 alpha-reductase 3 pseudogene 1

TECR Gene

trans-2,3-enoyl-CoA reductase

This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011]

SDR39U1 Gene

short chain dehydrogenase/reductase family 39U, member 1

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) superfamily, which includes both classical and extended types. The encoded protein represents an extended type, with similarity to epimerases. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]

LOC105371187 Gene

putative short-chain dehydrogenase/reductase family 42E member 2

Peptide methionine sulphoxide reductase MrsB Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide methionine sulphoxide reductase MrsB protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptide methionine sulphoxide reductase MsrA Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide methionine sulphoxide reductase MsrA protein domain from the InterPro Predicted Protein Domain Annotations dataset.

peptide-methionine (r)-s-oxide reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-methionine (r)-s-oxide reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide-methionine (s)-s-oxide reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-methionine (s)-s-oxide reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

Peptide methionine sulfoxide reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide methionine sulfoxide reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

[methionine synthase] reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the [methionine synthase] reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

methionine-r-sulfoxide reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the methionine-r-sulfoxide reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

FMRFamide-related peptide/Growth hormone-releasing peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the FMRFamide-related peptide/Growth hormone-releasing peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Methionine adenosyltransferase deficiency, autosomal recessive Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Methionine adenosyltransferase deficiency, autosomal recessive phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Methionine adenosyltransferase deficiency, autosomal dominant Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Methionine adenosyltransferase deficiency, autosomal dominant phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

L-methionine sulfoximine-4070 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the L-methionine sulfoximine-4070 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

L-methionine sulfoximine-2470 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the L-methionine sulfoximine-2470 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

L-methionine sulfoximine-4151 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the L-methionine sulfoximine-4151 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

L-methionine sulfoximine-2831 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the L-methionine sulfoximine-2831 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

methionine adenosyltransferase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the methionine adenosyltransferase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

methionine adenosyltransferase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the methionine adenosyltransferase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

methionine selenoxide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical methionine selenoxide from the curated CTD Gene-Chemical Interactions dataset.

Methionine Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Methionine from the curated CTD Gene-Chemical Interactions dataset.

Methionine Sulfoximine Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Methionine Sulfoximine from the curated CTD Gene-Chemical Interactions dataset.

Methionine Adenosyltransferase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Methionine Adenosyltransferase Deficiency from the curated CTD Gene-Disease Associations dataset.

D-Methionine Gene Set

From DrugBank Drug Targets

interacting proteins for the D-Methionine drug from the curated DrugBank Drug Targets dataset.

Methionine Sulfoxide Gene Set

From DrugBank Drug Targets

interacting proteins for the Methionine Sulfoxide drug from the curated DrugBank Drug Targets dataset.

L-Methionine Gene Set

From DrugBank Drug Targets

interacting proteins for the L-Methionine drug from the curated DrugBank Drug Targets dataset.

methionine adenosyltransferase i/iii deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease methionine adenosyltransferase i/iii deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

methionine Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term methionine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

methionine biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the methionine biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

peptidyl-methionine modification Gene Set

From GO Biological Process Annotations

genes participating in the peptidyl-methionine modification biological process from the curated GO Biological Process Annotations dataset.

l-methionine biosynthetic process from methylthioadenosine Gene Set

From GO Biological Process Annotations

genes participating in the l-methionine biosynthetic process from methylthioadenosine biological process from the curated GO Biological Process Annotations dataset.

l-methionine biosynthetic process from s-adenosylmethionine Gene Set

From GO Biological Process Annotations

genes participating in the l-methionine biosynthetic process from s-adenosylmethionine biological process from the curated GO Biological Process Annotations dataset.

methionine metabolic process Gene Set

From GO Biological Process Annotations

genes participating in the methionine metabolic process biological process from the curated GO Biological Process Annotations dataset.

s-adenosyl-l-methionine transport Gene Set

From GO Biological Process Annotations

genes participating in the s-adenosyl-l-methionine transport biological process from the curated GO Biological Process Annotations dataset.

methionine transport Gene Set

From GO Biological Process Annotations

genes participating in the methionine transport biological process from the curated GO Biological Process Annotations dataset.

n-terminal peptidyl-methionine acetylation Gene Set

From GO Biological Process Annotations

genes participating in the n-terminal peptidyl-methionine acetylation biological process from the curated GO Biological Process Annotations dataset.

l-methionine biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the l-methionine biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

s-adenosyl-l-methionine transmembrane transport Gene Set

From GO Biological Process Annotations

genes participating in the s-adenosyl-l-methionine transmembrane transport biological process from the curated GO Biological Process Annotations dataset.

l-methionine salvage Gene Set

From GO Biological Process Annotations

genes participating in the l-methionine salvage biological process from the curated GO Biological Process Annotations dataset.

protein initiator methionine removal Gene Set

From GO Biological Process Annotations

genes participating in the protein initiator methionine removal biological process from the curated GO Biological Process Annotations dataset.

methionine adenosyltransferase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the methionine adenosyltransferase complex cellular component from the curated GO Cellular Component Annotations dataset.

methionine adenosyltransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the methionine adenosyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

methionine-trna ligase activity Gene Set

From GO Molecular Function Annotations

genes performing the methionine-trna ligase activity molecular function from the curated GO Molecular Function Annotations dataset.

s-adenosyl-l-methionine transmembrane transporter activity Gene Set

From GO Molecular Function Annotations

genes performing the s-adenosyl-l-methionine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations dataset.

methionine adenosyltransferase regulator activity Gene Set

From GO Molecular Function Annotations

genes performing the methionine adenosyltransferase regulator activity molecular function from the curated GO Molecular Function Annotations dataset.

methionine synthase activity Gene Set

From GO Molecular Function Annotations

genes performing the methionine synthase activity molecular function from the curated GO Molecular Function Annotations dataset.

l-methionine transmembrane transporter activity Gene Set

From GO Molecular Function Annotations

genes performing the l-methionine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations dataset.

methionine transmembrane transporter activity Gene Set

From GO Molecular Function Annotations

genes performing the methionine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations dataset.

methionine benzimidazole 6 Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the methionine benzimidazole 6 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Plasma homocysteine levels (post-methionine load test) Gene Set

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Plasma homocysteine levels (post-methionine load test) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

N-Acetyl-L-methionine Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the N-Acetyl-L-methionine metabolite from the curated HMDB Metabolites of Enzymes dataset.

Methionine sulfoxide Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Methionine sulfoxide metabolite from the curated HMDB Metabolites of Enzymes dataset.

L-Methionine Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the L-Methionine metabolite from the curated HMDB Metabolites of Enzymes dataset.

abnormality of methionine metabolism Gene Set

From HPO Gene-Disease Associations

genes associated with the abnormality of methionine metabolism phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

decreased methionine synthase activity Gene Set

From HPO Gene-Disease Associations

genes associated with the decreased methionine synthase activity phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

methionine salvage Gene Set

From HumanCyc Pathways

proteins participating in the methionine salvage pathway from the HumanCyc Pathways dataset.

methionine degradation Gene Set

From HumanCyc Pathways

proteins participating in the methionine degradation pathway from the HumanCyc Pathways dataset.

S-adenosyl-L-methionine biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the S-adenosyl-L-methionine biosynthesis pathway from the HumanCyc Pathways dataset.

superpathway of methionine degradation Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of methionine degradation pathway from the HumanCyc Pathways dataset.

Vitamin B12-dependent methionine synthase, activation domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Vitamin B12-dependent methionine synthase, activation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

S-adenosyl-L-methionine dependent methyltransferase, Mett10D, predicted Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the S-adenosyl-L-methionine dependent methyltransferase, Mett10D, predicted protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptidase M24A, methionine aminopeptidase, subfamily 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase M24A, methionine aminopeptidase, subfamily 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Bin3-type S-adenosyl-L-methionine binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Bin3-type S-adenosyl-L-methionine binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Methionine-tRNA ligase, type 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methionine-tRNA ligase, type 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

S-adenosyl-L-methionine-dependent methyltransferase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the S-adenosyl-L-methionine-dependent methyltransferase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptidase M24A, methionine aminopeptidase, subfamily 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase M24A, methionine aminopeptidase, subfamily 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cobalamin-dependent methionine synthase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cobalamin-dependent methionine synthase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptidase M24, methionine aminopeptidase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase M24, methionine aminopeptidase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Putative S-adenosyl-L-methionine-dependent methyltransferase MidA protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Methionine tRNA Formyltransferase-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methionine tRNA Formyltransferase-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Methionine adenosyltransferase 2 subunit beta Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methionine adenosyltransferase 2 subunit beta protein domain from the InterPro Predicted Protein Domain Annotations dataset.

methionine metabolism Gene Set

From KEGG Pathways

proteins participating in the methionine metabolism pathway from the KEGG Pathways dataset.

methionine adenosyltransferase deficiency, autosomal recessive Gene Set

From OMIM Gene-Disease Associations

genes associated with the methionine adenosyltransferase deficiency, autosomal recessive phenotype from the curated OMIM Gene-Disease Associations dataset.

hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase i/iii deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase i/iii deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

Methionine biosynthesis Gene Set

From PANTHER Pathways

proteins participating in the Methionine biosynthesis pathway from the PANTHER Pathways dataset.

Methionine salvage pathway Gene Set

From Reactome Pathways

proteins participating in the Methionine salvage pathway pathway from the Reactome Pathways dataset.

Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Gene Set

From Reactome Pathways

proteins participating in the Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) pathway from the Reactome Pathways dataset.

Sepiapterin reductase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Sepiapterin reductase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Peroxisomal fatty acyl-coa reductase 1 disorder Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Peroxisomal fatty acyl-coa reductase 1 disorder phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

2,4-Dienoyl-CoA reductase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the 2,4-Dienoyl-CoA reductase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Deficiency of pyrroline-5-carboxylate reductase Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Deficiency of pyrroline-5-carboxylate reductase phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Cortisone reductase deficiency 2 Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Cortisone reductase deficiency 2 phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Dihydropteridine reductase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Dihydropteridine reductase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

Megaloblastic anemia due to dihydrofolate reductase deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the Megaloblastic anemia due to dihydrofolate reductase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

fumarate reductase complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the fumarate reductase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

fumarate reductase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the fumarate reductase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

ribonucleoside-diphosphate reductase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the ribonucleoside-diphosphate reductase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

glycine reductase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the glycine reductase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

nitrate reductase complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the nitrate reductase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Hydroxymethylglutaryl-CoA Reductase Inhibitors Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Hydroxymethylglutaryl-CoA Reductase Inhibitors from the curated CTD Gene-Chemical Interactions dataset.

Methylenetetrahydrofolate reductase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Methylenetetrahydrofolate reductase deficiency from the curated CTD Gene-Disease Associations dataset.

Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Dystonia, Dopa-Responsive, due to Sepiapterin Reductase Deficiency from the curated CTD Gene-Disease Associations dataset.

Cortisone reductase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Cortisone reductase deficiency from the curated CTD Gene-Disease Associations dataset.

NADH cytochrome B5 reductase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease NADH cytochrome B5 reductase deficiency from the curated CTD Gene-Disease Associations dataset.

2,4-Dienoyl-CoA Reductase Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease 2,4-Dienoyl-CoA Reductase Deficiency from the curated CTD Gene-Disease Associations dataset.

methylenetetrahydrofolate reductase deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease methylenetetrahydrofolate reductase deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

carbonyl reductase 1 Gene Set

From GAD Gene-Disease Associations

genes associated with the disease carbonyl reductase 1 in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

hmg-coa reductase inhibitors Gene Set

From GAD Gene-Disease Associations

genes associated with the disease hmg-coa reductase inhibitors in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

reductase Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term reductase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

regulation of pyrroline-5-carboxylate reductase activity Gene Set

From GO Biological Process Annotations

genes participating in the regulation of pyrroline-5-carboxylate reductase activity biological process from the curated GO Biological Process Annotations dataset.

positive regulation of pyrroline-5-carboxylate reductase activity Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of pyrroline-5-carboxylate reductase activity biological process from the curated GO Biological Process Annotations dataset.

gmp reductase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the gmp reductase complex cellular component from the curated GO Cellular Component Annotations dataset.

fumarate reductase complex Gene Set

From GO Cellular Component Annotations

proteins localized to the fumarate reductase complex cellular component from the curated GO Cellular Component Annotations dataset.

carbonyl reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the carbonyl reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

arsenate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the arsenate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

riboflavin reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the riboflavin reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

delta14-sterol reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the delta14-sterol reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

nadph-adrenodoxin reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the nadph-adrenodoxin reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

ferredoxin-nadp+ reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the ferredoxin-nadp+ reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

sepiapterin reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the sepiapterin reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

3-keto sterol reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-keto sterol reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

l-glucuronate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the l-glucuronate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

dihydronicotinamide riboside quinone reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the dihydronicotinamide riboside quinone reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

gdp-4-dehydro-d-rhamnose reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the gdp-4-dehydro-d-rhamnose reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

prostaglandin-e2 9-reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the prostaglandin-e2 9-reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

trans-2-enoyl-coa reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the trans-2-enoyl-coa reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

cholestenone 5-alpha-reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the cholestenone 5-alpha-reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

enoyl-[acyl-carrier-protein] reductase (nadph, a-specific) activity Gene Set

From GO Molecular Function Annotations

genes performing the enoyl-[acyl-carrier-protein] reductase (nadph, a-specific) activity molecular function from the curated GO Molecular Function Annotations dataset.

nadph-hemoprotein reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the nadph-hemoprotein reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

nitrate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the nitrate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

dihydrofolate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the dihydrofolate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

iron-cytochrome-c reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the iron-cytochrome-c reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

mercury (ii) reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the mercury (ii) reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

cupric reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the cupric reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

delta24-sterol reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the delta24-sterol reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

2-alkenal reductase [nad(p)] activity Gene Set

From GO Molecular Function Annotations

genes performing the 2-alkenal reductase [nad(p)] activity molecular function from the curated GO Molecular Function Annotations dataset.

3-dehydrosphinganine reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-dehydrosphinganine reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

cytochrome-b5 reductase activity, acting on nad(p)h Gene Set

From GO Molecular Function Annotations

genes performing the cytochrome-b5 reductase activity, acting on nad(p)h molecular function from the curated GO Molecular Function Annotations dataset.

ferric-chelate reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the ferric-chelate reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

6,7-dihydropteridine reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the 6,7-dihydropteridine reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

l-xylulose reductase (nadp+) activity Gene Set

From GO Molecular Function Annotations

genes performing the l-xylulose reductase (nadp+) activity molecular function from the curated GO Molecular Function Annotations dataset.

protein-disulfide reductase (glutathione) activity Gene Set

From GO Molecular Function Annotations

genes performing the protein-disulfide reductase (glutathione) activity molecular function from the curated GO Molecular Function Annotations dataset.

aldo-keto reductase (nadp) activity Gene Set

From GO Molecular Function Annotations

genes performing the aldo-keto reductase (nadp) activity molecular function from the curated GO Molecular Function Annotations dataset.

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Gene Set

From GO Molecular Function Annotations

genes performing the ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor molecular function from the curated GO Molecular Function Annotations dataset.

glyoxylate reductase (nadp) activity Gene Set

From GO Molecular Function Annotations

genes performing the glyoxylate reductase (nadp) activity molecular function from the curated GO Molecular Function Annotations dataset.

geranylgeranyl reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the geranylgeranyl reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

chlordecone reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the chlordecone reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

glutathione-disulfide reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the glutathione-disulfide reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

gmp reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the gmp reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

long-chain-fatty-acyl-coa reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the long-chain-fatty-acyl-coa reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

[hydroxymethylglutaryl-coa reductase (nadph)] kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the [hydroxymethylglutaryl-coa reductase (nadph)] kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

1,5-anhydro-d-fructose reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the 1,5-anhydro-d-fructose reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

enone reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the enone reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

enoyl-[acyl-carrier-protein] reductase (nadph, b-specific) activity Gene Set

From GO Molecular Function Annotations

genes performing the enoyl-[acyl-carrier-protein] reductase (nadph, b-specific) activity molecular function from the curated GO Molecular Function Annotations dataset.

2,4-dienoyl-coa reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the 2,4-dienoyl-coa reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

arsenate reductase (glutaredoxin) activity Gene Set

From GO Molecular Function Annotations

genes performing the arsenate reductase (glutaredoxin) activity molecular function from the curated GO Molecular Function Annotations dataset.

all-trans-retinol 13,14-reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the all-trans-retinol 13,14-reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

thioredoxin-disulfide reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the thioredoxin-disulfide reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

ubiquinol-cytochrome-c reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the ubiquinol-cytochrome-c reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

methylenetetrahydrofolate reductase (nad(p)h) activity Gene Set

From GO Molecular Function Annotations

genes performing the methylenetetrahydrofolate reductase (nad(p)h) activity molecular function from the curated GO Molecular Function Annotations dataset.

pyrroline-5-carboxylate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the pyrroline-5-carboxylate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

7-dehydrocholesterol reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the 7-dehydrocholesterol reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

methylarsonate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the methylarsonate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

biliverdin reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the biliverdin reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

13-prostaglandin reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the 13-prostaglandin reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

electron transporter, transferring electrons from coqh2-cytochrome c reductase complex and cytochrome c oxidase complex activity Gene Set

From GO Molecular Function Annotations

genes performing the electron transporter, transferring electrons from coqh2-cytochrome c reductase complex and cytochrome c oxidase complex activity molecular function from the curated GO Molecular Function Annotations dataset.

3-oxoacyl-[acyl-carrier-protein] reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the 3-oxoacyl-[acyl-carrier-protein] reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

fatty-acyl-coa reductase (alcohol-forming) activity Gene Set

From GO Molecular Function Annotations

genes performing the fatty-acyl-coa reductase (alcohol-forming) activity molecular function from the curated GO Molecular Function Annotations dataset.

vitamin-k-epoxide reductase (warfarin-sensitive) activity Gene Set

From GO Molecular Function Annotations

genes performing the vitamin-k-epoxide reductase (warfarin-sensitive) activity molecular function from the curated GO Molecular Function Annotations dataset.

diiodophenylpyruvate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the diiodophenylpyruvate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

delta24(24-1) sterol reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the delta24(24-1) sterol reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

sterol 5-alpha reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the sterol 5-alpha reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

ferric-chelate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the ferric-chelate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

hydroxymethylglutaryl-coa reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the hydroxymethylglutaryl-coa reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

nadph:quinone reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the nadph:quinone reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

aquacobalamin reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the aquacobalamin reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

hydroxypyruvate reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the hydroxypyruvate reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

alkyl hydroperoxide reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the alkyl hydroperoxide reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

delta4-3-oxosteroid 5beta-reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the delta4-3-oxosteroid 5beta-reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

hydroxymethylglutaryl-coa reductase (nadph) activity Gene Set

From GO Molecular Function Annotations

genes performing the hydroxymethylglutaryl-coa reductase (nadph) activity molecular function from the curated GO Molecular Function Annotations dataset.

protein-disulfide reductase activity Gene Set

From GO Molecular Function Annotations

genes performing the protein-disulfide reductase activity molecular function from the curated GO Molecular Function Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Biliverdin reductase, catalytic Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Biliverdin reductase, catalytic protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Flavoprotein pyridine nucleotide cytochrome reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Flavoprotein pyridine nucleotide cytochrome reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribonucleotide reductase R1 subunit, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribonucleotide reductase R1 subunit, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribonucleotide reductase-related Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribonucleotide reductase-related protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH-ubiquinone reductase complex 1 MLRQ subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH-ubiquinone reductase complex 1 MLRQ subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Biliverdin reductase A Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Biliverdin reductase A protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Gamma-glutamyl phosphate reductase GPR Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Gamma-glutamyl phosphate reductase GPR protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cytochrome b561/ferric reductase transmembrane Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cytochrome b561/ferric reductase transmembrane protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADPH-cytochrome P450 reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADPH-cytochrome P450 reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Protein-tyrosine phosphatase/arsenate reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein-tyrosine phosphatase/arsenate reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Thioredoxin/glutathione reductase selenoprotein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Thioredoxin/glutathione reductase selenoprotein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Guanosine monophosphate reductase 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Guanosine monophosphate reductase 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Methylenetetrahydrofolate reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methylenetetrahydrofolate reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/Fumarate reductase, transmembrane subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/Fumarate reductase, transmembrane subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Pyrroline-5-carboxylate reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pyrroline-5-carboxylate reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

dTDP-4-dehydrorhamnose reductase family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the dTDP-4-dehydrorhamnose reductase family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydrofolate reductase-like domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydrofolate reductase-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ferredoxin-NADP+ reductase, adrenodoxin-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ferredoxin-NADP+ reductase, adrenodoxin-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Gamma interferon inducible lysosomal thiol reductase GILT Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Gamma interferon inducible lysosomal thiol reductase GILT protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cytochrome b reductase 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cytochrome b reductase 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydrofolate reductase domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydrofolate reductase domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ubiquinol cytochrome reductase, transmembrane domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ubiquinol cytochrome reductase, transmembrane domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ubiquinol-cytochrome C reductase hinge domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ubiquinol-cytochrome C reductase hinge domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ferric reductase, NAD binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ferric reductase, NAD binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dehydrogenase/reductase SDR member 4-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dehydrogenase/reductase SDR member 4-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribonucleotide reductase, class I , alpha subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribonucleotide reductase, class I , alpha subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/fumarate reductase, flavoprotein subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Gamma-glutamyl phosphate reductase GPR, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Gamma-glutamyl phosphate reductase GPR, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

IMP dehydrogenase/GMP reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the IMP dehydrogenase/GMP reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydogenase/fumarate reductase N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydogenase/fumarate reductase N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Pyrroline-5-carboxylate reductase, dimerisation domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pyrroline-5-carboxylate reductase, dimerisation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribonucleotide reductase small subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribonucleotide reductase small subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribonucleotide reductase large subunit, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribonucleotide reductase large subunit, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dehydrogenase/reductase SDR member 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dehydrogenase/reductase SDR member 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldo/keto reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldo/keto reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ubiquinol-cytochrome c reductase, iron-sulphur subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ubiquinol-cytochrome c reductase, iron-sulphur subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

FAD/NAD-linked reductase, dimerisation domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the FAD/NAD-linked reductase, dimerisation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Succinate dehydrogenase/fumarate reductase iron-sulphur protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate dehydrogenase/fumarate reductase iron-sulphur protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Fumarate reductase/succinate dehydrogenase, FAD-binding site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fumarate reductase/succinate dehydrogenase, FAD-binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldo/keto reductase subgroup Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldo/keto reductase subgroup protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH:cytochrome b5 reductase (CBR) Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH:cytochrome b5 reductase (CBR) protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Eukaryotic-type methylenetetrahydrofolate reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic-type methylenetetrahydrofolate reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cytochrome cd1-nitrite reductase-like, haem d1 domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cytochrome cd1-nitrite reductase-like, haem d1 domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

IMP dehydrogenase / GMP reductase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the IMP dehydrogenase / GMP reductase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, metazoan Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, metazoan protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Sepiapterin reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sepiapterin reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Short-chain dehydrogenase/reductase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Short-chain dehydrogenase/reductase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Pyrroline-5-carboxylate reductase, catalytic, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pyrroline-5-carboxylate reductase, catalytic, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Vitamin K epoxide reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Vitamin K epoxide reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ferredoxin reductase-type FAD-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ferredoxin reductase-type FAD-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Aldo/keto reductase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Aldo/keto reductase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ferric reductase transmembrane component-like domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ferric reductase transmembrane component-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Phosphoadenosine phosphosulphate reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphoadenosine phosphosulphate reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glutathione reductase, eukaryote/bacterial Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glutathione reductase, eukaryote/bacterial protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Short-chain dehydrogenase/reductase SDR Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Short-chain dehydrogenase/reductase SDR protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Sterol reductase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sterol reductase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Fatty acyl-CoA reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fatty acyl-CoA reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Nitrous oxide reductase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Nitrous oxide reductase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydrofolate reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydrofolate reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dihydrofolate reductase conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dihydrofolate reductase conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Phenol hydroxylase reductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phenol hydroxylase reductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Reductase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Reductase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Hydroxymethylglutaryl-CoA reductase, class I/II Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hydroxymethylglutaryl-CoA reductase, class I/II protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ubiquinol-cytochrome c reductase 8kDa, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ubiquinol-cytochrome c reductase 8kDa, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribonucleotide reductase large subunit, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribonucleotide reductase large subunit, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

megaloblastic anemia due to dihydrofolate reductase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the megaloblastic anemia due to dihydrofolate reductase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

?2,4-dienoyl-coa reductase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the ?2,4-dienoyl-coa reductase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

hemolytic anemia due to glutathione reductase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the hemolytic anemia due to glutathione reductase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

dystonia, dopa-responsive, due to sepiapterin reductase deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the dystonia, dopa-responsive, due to sepiapterin reductase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

cortisone reductase deficiency 2 Gene Set

From OMIM Gene-Disease Associations

genes associated with the cortisone reductase deficiency 2 phenotype from the curated OMIM Gene-Disease Associations dataset.

cortisone reductase deficiency 1 Gene Set

From OMIM Gene-Disease Associations

genes associated with the cortisone reductase deficiency 1 phenotype from the curated OMIM Gene-Disease Associations dataset.

peroxisomal fatty acyl-coa reductase 1 disorder Gene Set

From OMIM Gene-Disease Associations

genes associated with the peroxisomal fatty acyl-coa reductase 1 disorder phenotype from the curated OMIM Gene-Disease Associations dataset.

bioactive peptide induced signaling pathway Gene Set

From Biocarta Pathways

proteins participating in the bioactive peptide induced signaling pathway pathway from the Biocarta Pathways dataset.

generation of amyloid b-peptide by ps1 Gene Set

From Biocarta Pathways

proteins participating in the generation of amyloid b-peptide by ps1 pathway from the Biocarta Pathways dataset.

mhc class i peptide loading complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mhc class i peptide loading complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

mhc class i peptide loading complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mhc class i peptide loading complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Dendroaspis natriuretic peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Dendroaspis natriuretic peptide from the curated CTD Gene-Chemical Interactions dataset.

surfactin peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical surfactin peptide from the curated CTD Gene-Chemical Interactions dataset.

SN50 peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical SN50 peptide from the curated CTD Gene-Chemical Interactions dataset.

PAR-1-activating peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical PAR-1-activating peptide from the curated CTD Gene-Chemical Interactions dataset.

polysaccharide peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical polysaccharide peptide from the curated CTD Gene-Chemical Interactions dataset.

p-271 peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical p-271 peptide from the curated CTD Gene-Chemical Interactions dataset.

hirulog-like peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical hirulog-like peptide from the curated CTD Gene-Chemical Interactions dataset.

R18 peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical R18 peptide from the curated CTD Gene-Chemical Interactions dataset.

VIVIT peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical VIVIT peptide from the curated CTD Gene-Chemical Interactions dataset.

F-180 vasoconstrictor peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical F-180 vasoconstrictor peptide from the curated CTD Gene-Chemical Interactions dataset.

BPC96 peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical BPC96 peptide from the curated CTD Gene-Chemical Interactions dataset.

vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)- Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)- from the curated CTD Gene-Chemical Interactions dataset.

Leu-Ser-Lys-Leu peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Leu-Ser-Lys-Leu peptide from the curated CTD Gene-Chemical Interactions dataset.

protein kinase inhibitor peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical protein kinase inhibitor peptide from the curated CTD Gene-Chemical Interactions dataset.

MK2i peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical MK2i peptide from the curated CTD Gene-Chemical Interactions dataset.

myristoylated autocamtide-2-related inhibitory peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical myristoylated autocamtide-2-related inhibitory peptide from the curated CTD Gene-Chemical Interactions dataset.

Pam(3)CSK(4) peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Pam(3)CSK(4) peptide from the curated CTD Gene-Chemical Interactions dataset.

thrombin receptor-activating peptide SFLLRNPNDKY Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical thrombin receptor-activating peptide SFLLRNPNDKY from the curated CTD Gene-Chemical Interactions dataset.

calcitonin gene-related peptide (8-37) Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical calcitonin gene-related peptide (8-37) from the curated CTD Gene-Chemical Interactions dataset.

connective tissue-activating peptide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical connective tissue-activating peptide from the curated CTD Gene-Chemical Interactions dataset.

Natriuretic Peptide, Brain Gene Set

From dbGAP Gene-Trait Associations

genes associated with the trait Natriuretic Peptide, Brain in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

diabetes, type 2; insulin; glucose; c-peptide; fatty acid Gene Set

From GAD Gene-Disease Associations

genes associated with the disease diabetes, type 2; insulin; glucose; c-peptide; fatty acid in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

reduced serum c-peptide and insulin responses to an oral glucose challenge Gene Set

From GAD Gene-Disease Associations

genes associated with the disease reduced serum c-peptide and insulin responses to an oral glucose challenge in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

atrial natriuretic peptide activity after exercise Gene Set

From GAD Gene-Disease Associations

genes associated with the disease atrial natriuretic peptide activity after exercise in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

body mass; glucose tolerance; insulin; blood pressure; c-peptide; hba1c Gene Set

From GAD Gene-Disease Associations

genes associated with the disease body mass; glucose tolerance; insulin; blood pressure; c-peptide; hba1c in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

anti-cyclic citrullianted peptide antibody Gene Set

From GAD Gene-Disease Associations

genes associated with the disease anti-cyclic citrullianted peptide antibody in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

natriuretic peptide, brain Gene Set

From GAD Gene-Disease Associations

genes associated with the disease natriuretic peptide, brain in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

insulin; lipoproteins; c-peptide; proinsulin Gene Set

From GAD Gene-Disease Associations

genes associated with the disease insulin; lipoproteins; c-peptide; proinsulin in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

insulin; glucose; c-peptide; fatty acid Gene Set

From GAD Gene-Disease Associations

genes associated with the disease insulin; glucose; c-peptide; fatty acid in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

lipids; glucose; c-peptide Gene Set

From GAD Gene-Disease Associations

genes associated with the disease lipids; glucose; c-peptide in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucose tolerance; insulin; blood pressure; body weight; c-peptide; hba1c Gene Set

From GAD Gene-Disease Associations

genes associated with the disease glucose tolerance; insulin; blood pressure; body weight; c-peptide; hba1c in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

peptide Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term peptide in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

antigen processing and presentation of exogenous peptide antigen via mhc class i Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of exogenous peptide antigen via mhc class i biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of endogenous peptide antigen Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of endogenous peptide antigen biological process from the curated GO Biological Process Annotations dataset.

negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

regulation of peptide transport Gene Set

From GO Biological Process Annotations

genes participating in the regulation of peptide transport biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway biological process from the curated GO Biological Process Annotations dataset.

negative regulation of antigen processing and presentation of peptide antigen via mhc class i Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of antigen processing and presentation of peptide antigen via mhc class i biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antimicrobial peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antimicrobial peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of peptide secretion Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of peptide secretion biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antigen processing and presentation of peptide antigen Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antigen processing and presentation of peptide antigen biological process from the curated GO Biological Process Annotations dataset.

gastric inhibitory peptide signaling pathway Gene Set

From GO Biological Process Annotations

genes participating in the gastric inhibitory peptide signaling pathway biological process from the curated GO Biological Process Annotations dataset.

negative regulation of antigen processing and presentation of peptide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of antigen processing and presentation of peptide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

regulation of antigen processing and presentation of peptide antigen via mhc class i Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antigen processing and presentation of peptide antigen via mhc class i biological process from the curated GO Biological Process Annotations dataset.

regulation of antigen processing and presentation of peptide antigen Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antigen processing and presentation of peptide antigen biological process from the curated GO Biological Process Annotations dataset.

antibacterial peptide secretion Gene Set

From GO Biological Process Annotations

genes participating in the antibacterial peptide secretion biological process from the curated GO Biological Process Annotations dataset.

positive regulation of peptide hormone secretion Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of peptide hormone secretion biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of peptide antigen via mhc class i Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of peptide antigen via mhc class i biological process from the curated GO Biological Process Annotations dataset.

regulation of antimicrobial peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antimicrobial peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of endogenous peptide antigen via mhc class ib Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of endogenous peptide antigen via mhc class ib biological process from the curated GO Biological Process Annotations dataset.

peptide antigen assembly with mhc class ii protein complex Gene Set

From GO Biological Process Annotations

genes participating in the peptide antigen assembly with mhc class ii protein complex biological process from the curated GO Biological Process Annotations dataset.

regulation of antibacterial peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antibacterial peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

regulation of peptide hormone secretion Gene Set

From GO Biological Process Annotations

genes participating in the regulation of peptide hormone secretion biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of exogenous peptide antigen via mhc class i, tap-dependent Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of exogenous peptide antigen via mhc class i, tap-dependent biological process from the curated GO Biological Process Annotations dataset.

peptide cross-linking Gene Set

From GO Biological Process Annotations

genes participating in the peptide cross-linking biological process from the curated GO Biological Process Annotations dataset.

negative regulation of peptide secretion Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of peptide secretion biological process from the curated GO Biological Process Annotations dataset.

peptide amidation Gene Set

From GO Biological Process Annotations

genes participating in the peptide amidation biological process from the curated GO Biological Process Annotations dataset.

regulation of antimicrobial peptide production Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antimicrobial peptide production biological process from the curated GO Biological Process Annotations dataset.

peptide secretion Gene Set

From GO Biological Process Annotations

genes participating in the peptide secretion biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antibacterial peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antibacterial peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

signal peptide processing Gene Set

From GO Biological Process Annotations

genes participating in the signal peptide processing biological process from the curated GO Biological Process Annotations dataset.

peptide antigen transport Gene Set

From GO Biological Process Annotations

genes participating in the peptide antigen transport biological process from the curated GO Biological Process Annotations dataset.

negative regulation of antigen processing and presentation of peptide antigen Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of antigen processing and presentation of peptide antigen biological process from the curated GO Biological Process Annotations dataset.

peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase Gene Set

From GO Biological Process Annotations

genes participating in the peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

antimicrobial peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the antimicrobial peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

peptide antigen stabilization Gene Set

From GO Biological Process Annotations

genes participating in the peptide antigen stabilization biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway, tap-dependent Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway, tap-dependent biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of exogenous peptide antigen Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of exogenous peptide antigen biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of peptide antigen Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of peptide antigen biological process from the curated GO Biological Process Annotations dataset.

peptide transport Gene Set

From GO Biological Process Annotations

genes participating in the peptide transport biological process from the curated GO Biological Process Annotations dataset.

antimicrobial peptide secretion Gene Set

From GO Biological Process Annotations

genes participating in the antimicrobial peptide secretion biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of peptide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of peptide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of peptide antigen via mhc class ib Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of peptide antigen via mhc class ib biological process from the curated GO Biological Process Annotations dataset.

peptide hormone secretion Gene Set

From GO Biological Process Annotations

genes participating in the peptide hormone secretion biological process from the curated GO Biological Process Annotations dataset.

regulation of systemic arterial blood pressure by atrial natriuretic peptide Gene Set

From GO Biological Process Annotations

genes participating in the regulation of systemic arterial blood pressure by atrial natriuretic peptide biological process from the curated GO Biological Process Annotations dataset.

peptide catabolic process Gene Set

From GO Biological Process Annotations

genes participating in the peptide catabolic process biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway biological process from the curated GO Biological Process Annotations dataset.

peptide hormone processing Gene Set

From GO Biological Process Annotations

genes participating in the peptide hormone processing biological process from the curated GO Biological Process Annotations dataset.

regulation of peptide secretion Gene Set

From GO Biological Process Annotations

genes participating in the regulation of peptide secretion biological process from the curated GO Biological Process Annotations dataset.

peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan Gene Set

From GO Biological Process Annotations

genes participating in the peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of endogenous peptide antigen via mhc class i Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of endogenous peptide antigen via mhc class i biological process from the curated GO Biological Process Annotations dataset.

antibacterial peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the antibacterial peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway, tap-dependent Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway, tap-dependent biological process from the curated GO Biological Process Annotations dataset.

cellular response to peptide hormone stimulus Gene Set

From GO Biological Process Annotations

genes participating in the cellular response to peptide hormone stimulus biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antimicrobial peptide production Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antimicrobial peptide production biological process from the curated GO Biological Process Annotations dataset.

response to peptide hormone Gene Set

From GO Biological Process Annotations

genes participating in the response to peptide hormone biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antigen processing and presentation of peptide antigen via mhc class i Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antigen processing and presentation of peptide antigen via mhc class i biological process from the curated GO Biological Process Annotations dataset.

nonribosomal peptide biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the nonribosomal peptide biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

cellular response to peptide Gene Set

From GO Biological Process Annotations

genes participating in the cellular response to peptide biological process from the curated GO Biological Process Annotations dataset.

negative regulation of peptide hormone secretion Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of peptide hormone secretion biological process from the curated GO Biological Process Annotations dataset.

peptide stabilization Gene Set

From GO Biological Process Annotations

genes participating in the peptide stabilization biological process from the curated GO Biological Process Annotations dataset.

peptide modification Gene Set

From GO Biological Process Annotations

genes participating in the peptide modification biological process from the curated GO Biological Process Annotations dataset.

response to peptide Gene Set

From GO Biological Process Annotations

genes participating in the response to peptide biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of exogenous peptide antigen via mhc class i, tap-independent Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of exogenous peptide antigen via mhc class i, tap-independent biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

peptide antigen assembly with mhc class i protein complex Gene Set

From GO Biological Process Annotations

genes participating in the peptide antigen assembly with mhc class i protein complex biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antibacterial peptide production Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antibacterial peptide production biological process from the curated GO Biological Process Annotations dataset.

peptide antigen assembly with mhc protein complex Gene Set

From GO Biological Process Annotations

genes participating in the peptide antigen assembly with mhc protein complex biological process from the curated GO Biological Process Annotations dataset.

positive regulation of antigen processing and presentation of peptide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of antigen processing and presentation of peptide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

peptide metabolic process Gene Set

From GO Biological Process Annotations

genes participating in the peptide metabolic process biological process from the curated GO Biological Process Annotations dataset.

regulation of antibacterial peptide production Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antibacterial peptide production biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of exogenous peptide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of exogenous peptide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

antigen processing and presentation of exogenous peptide antigen via mhc class ib Gene Set

From GO Biological Process Annotations

genes participating in the antigen processing and presentation of exogenous peptide antigen via mhc class ib biological process from the curated GO Biological Process Annotations dataset.

regulation of antigen processing and presentation of peptide antigen via mhc class ii Gene Set

From GO Biological Process Annotations

genes participating in the regulation of antigen processing and presentation of peptide antigen via mhc class ii biological process from the curated GO Biological Process Annotations dataset.

mhc class i peptide loading complex Gene Set

From GO Cellular Component Annotations

proteins localized to the mhc class i peptide loading complex cellular component from the curated GO Cellular Component Annotations dataset.

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines Gene Set

From GO Molecular Function Annotations

genes performing the hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines molecular function from the curated GO Molecular Function Annotations dataset.

peptide disulfide oxidoreductase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide disulfide oxidoreductase activity molecular function from the curated GO Molecular Function Annotations dataset.

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides Gene Set

From GO Molecular Function Annotations

genes performing the hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides molecular function from the curated GO Molecular Function Annotations dataset.

peptide antigen binding Gene Set

From GO Molecular Function Annotations

genes performing the peptide antigen binding molecular function from the curated GO Molecular Function Annotations dataset.

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Gene Set

From GO Molecular Function Annotations

genes performing the hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds molecular function from the curated GO Molecular Function Annotations dataset.

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines Gene Set

From GO Molecular Function Annotations

genes performing the hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines molecular function from the curated GO Molecular Function Annotations dataset.

peptide-serine-n-acetyltransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-serine-n-acetyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

g-protein coupled peptide receptor activity Gene Set

From GO Molecular Function Annotations

genes performing the g-protein coupled peptide receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

proton-dependent peptide secondary active transmembrane transporter activity Gene Set

From GO Molecular Function Annotations

genes performing the proton-dependent peptide secondary active transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide:proton symporter activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide:proton symporter activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide-glutamate-n-acetyltransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-glutamate-n-acetyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

glutaminyl-peptide cyclotransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the glutaminyl-peptide cyclotransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

endoplasmic reticulum signal peptide binding Gene Set

From GO Molecular Function Annotations

genes performing the endoplasmic reticulum signal peptide binding molecular function from the curated GO Molecular Function Annotations dataset.

peptide-n4-(n-acetyl-beta-glucosaminyl)asparagine amidase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-n4-(n-acetyl-beta-glucosaminyl)asparagine amidase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide alpha-n-acetyltransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide alpha-n-acetyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide receptor activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide antigen-transporting atpase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide antigen-transporting atpase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide-aspartate beta-dioxygenase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-aspartate beta-dioxygenase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide deformylase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide deformylase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide hormone binding Gene Set

From GO Molecular Function Annotations

genes performing the peptide hormone binding molecular function from the curated GO Molecular Function Annotations dataset.

n-formyl peptide receptor activity Gene Set

From GO Molecular Function Annotations

genes performing the n-formyl peptide receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Gene Set

From GO Molecular Function Annotations

genes performing the hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides molecular function from the curated GO Molecular Function Annotations dataset.

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles Gene Set

From GO Molecular Function Annotations

genes performing the hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles molecular function from the curated GO Molecular Function Annotations dataset.

peptide hormone receptor binding Gene Set

From GO Molecular Function Annotations

genes performing the peptide hormone receptor binding molecular function from the curated GO Molecular Function Annotations dataset.

opioid peptide activity Gene Set

From GO Molecular Function Annotations

genes performing the opioid peptide activity molecular function from the curated GO Molecular Function Annotations dataset.

prolactin-releasing peptide receptor binding Gene Set

From GO Molecular Function Annotations

genes performing the prolactin-releasing peptide receptor binding molecular function from the curated GO Molecular Function Annotations dataset.

peptide yy receptor activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide yy receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

calcitonin gene-related peptide receptor activity Gene Set

From GO Molecular Function Annotations

genes performing the calcitonin gene-related peptide receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide binding Gene Set

From GO Molecular Function Annotations

genes performing the peptide binding molecular function from the curated GO Molecular Function Annotations dataset.

gastric inhibitory peptide receptor activity Gene Set

From GO Molecular Function Annotations

genes performing the gastric inhibitory peptide receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

natriuretic peptide receptor activity Gene Set

From GO Molecular Function Annotations

genes performing the natriuretic peptide receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide n-acetyltransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide n-acetyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide-transporting atpase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-transporting atpase activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide transporter activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide transporter activity molecular function from the curated GO Molecular Function Annotations dataset.

peptide-o-fucosyltransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the peptide-o-fucosyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

chemerin C-terminal peptide Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the chemerin C-terminal peptide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

R3(BΔ23-27)R/I5 chimeric peptide Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the R3(BΔ23-27)R/I5 chimeric peptide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[35S]non-peptide OT antagonist Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [35S]non-peptide OT antagonist ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

F peptide Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the F peptide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

MHC binding peptide Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the MHC binding peptide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

V3 peptide Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the V3 peptide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

gastrin releasing peptide (14-27) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the gastrin releasing peptide (14-27) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

peptide III-BTD Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the peptide III-BTD ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

peptide 234 Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the peptide 234 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

mast cell degranulating peptide Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the mast cell degranulating peptide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Circulating vasoactive peptide levels Gene Set

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Circulating vasoactive peptide levels phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Plasma amyloid beta peptide concentrations (ABx-42) Gene Set

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Plasma amyloid beta peptide concentrations (ABx-42) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Anti-cyclic Citrullinated Peptide Antibody Gene Set

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Anti-cyclic Citrullinated Peptide Antibody phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Plasma amyloid beta peptide concentrations (ABx-40) Gene Set

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Plasma amyloid beta peptide concentrations (ABx-40) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Follicular dendritic cell secreted peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Follicular dendritic cell secreted peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptidase A22B, signal peptide peptidase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase A22B, signal peptide peptidase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Prolactin-releasing peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Prolactin-releasing peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Natriuretic peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Natriuretic peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Motilin/ghrelin-associated peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Motilin/ghrelin-associated peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

KiSS-1 peptide receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the KiSS-1 peptide receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Natriuretic peptide, C type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Natriuretic peptide, C type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptide N glycanase, PAW domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide N glycanase, PAW domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Insulin-like peptide 6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Insulin-like peptide 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Atrial natriuretic peptide-converting enzyme corin Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Atrial natriuretic peptide-converting enzyme corin protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Gastrin-releasing peptide receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Gastrin-releasing peptide receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HSP40/DnaJ peptide-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HSP40/DnaJ peptide-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Prolactin-releasing peptide receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Prolactin-releasing peptide receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Natriuretic peptide, atrial type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Natriuretic peptide, atrial type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Formyl peptide receptor-related Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Formyl peptide receptor-related protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Galanin message associated peptide (GMAP) Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Galanin message associated peptide (GMAP) protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Gastrin releasing peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Gastrin releasing peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptide chain release factor class I/class II Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide chain release factor class I/class II protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Calcitonin peptide-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Calcitonin peptide-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptide chain release factor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide chain release factor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptide deformylase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide deformylase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Formyl peptide receptor 2/3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Formyl peptide receptor 2/3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPCR, family 2, glucagon-like peptide-1/glucagon receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, glucagon-like peptide-1/glucagon receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Preproghrelin peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Preproghrelin peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPCR, family 2, vasoactive intestinal peptide receptor 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, vasoactive intestinal peptide receptor 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPCR, family 2, vasoactive intestinal peptide receptor 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, vasoactive intestinal peptide receptor 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Natriuretic peptide, brain type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Natriuretic peptide, brain type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptide Chain Release Factor eRF1/aRF1, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide Chain Release Factor eRF1/aRF1, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Liver-expressed antimicrobial peptide 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Liver-expressed antimicrobial peptide 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPCR, family 2, calcitonin gene-related peptide, type 1 receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, calcitonin gene-related peptide, type 1 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPCR, family 2, vasoactive intestinal peptide receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, vasoactive intestinal peptide receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptide chain release factor eRF1/aRF1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptide chain release factor eRF1/aRF1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Bombesin/neuromedin-B/ranatensin peptide family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Bombesin/neuromedin-B/ranatensin peptide family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Vasoactive intestinal peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Vasoactive intestinal peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Heat shock protein 70kD, peptide-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Heat shock protein 70kD, peptide-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Antigen peptide transporter 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Antigen peptide transporter 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Antigen peptide transporter 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Antigen peptide transporter 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Calcitonin gene-related peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Calcitonin gene-related peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Insulin-like growth factor II E-peptide, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Insulin-like growth factor II E-peptide, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Amyloidogenic glycoprotein, amyloid-beta peptide Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Amyloidogenic glycoprotein, amyloid-beta peptide protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cathelicidin, antimicrobial peptide, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cathelicidin, antimicrobial peptide, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Natriuretic peptide receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Natriuretic peptide receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Gastrin/cholecystokinin peptide hormone Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Gastrin/cholecystokinin peptide hormone protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Presenilin/signal peptide peptidase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Presenilin/signal peptide peptidase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Formyl peptide receptor 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Formyl peptide receptor 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPCR, family 2, glucagon-like peptide-1 receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, glucagon-like peptide-1 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tuberoinfundibular peptide of 39 residues Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tuberoinfundibular peptide of 39 residues protein domain from the InterPro Predicted Protein Domain Annotations dataset.

abnormal circulating pancreatic peptide level Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal circulating pancreatic peptide level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

abnormal intercellular signaling peptide or protein level Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal intercellular signaling peptide or protein level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Peptide hormone metabolism Gene Set

From Reactome Pathways

proteins participating in the Peptide hormone metabolism pathway from the Reactome Pathways dataset.

Formyl peptide receptors bind formyl peptides and many other ligands Gene Set

From Reactome Pathways

proteins participating in the Formyl peptide receptors bind formyl peptides and many other ligands pathway from the Reactome Pathways dataset.

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Gene Set

From Reactome Pathways

proteins participating in the Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway from the Reactome Pathways dataset.

Peptide ligand-binding receptors Gene Set

From Reactome Pathways

proteins participating in the Peptide ligand-binding receptors pathway from the Reactome Pathways dataset.

Peptide hormone biosynthesis Gene Set

From Reactome Pathways

proteins participating in the Peptide hormone biosynthesis pathway from the Reactome Pathways dataset.

Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Gene Set

From Reactome Pathways

proteins participating in the Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway from the Reactome Pathways dataset.

Peptide chain elongation Gene Set

From Reactome Pathways

proteins participating in the Peptide chain elongation pathway from the Reactome Pathways dataset.

Antigen Presentation: Folding, assembly and peptide loading of class I MHC Gene Set

From Reactome Pathways

proteins participating in the Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway from the Reactome Pathways dataset.

Peptide GPCRs(Mus musculus) Gene Set

From Wikipathways Pathways

proteins participating in the Peptide GPCRs(Mus musculus) pathway from the Wikipathways Pathways dataset.

Peptide GPCRs(Homo sapiens) Gene Set

From Wikipathways Pathways

proteins participating in the Peptide GPCRs(Homo sapiens) pathway from the Wikipathways Pathways dataset.