Name

INPP4A Gene

inositol polyphosphate-4-phosphatase, type I, 107kDa

This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008]

ISYNA1 Gene

inositol-3-phosphate synthase 1

This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]

CDIPT Gene

CDP-diacylglycerol--inositol 3-phosphatidyltransferase

Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

IPMK Gene

inositol polyphosphate multikinase

This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010]

IP6K3 Gene

inositol hexakisphosphate kinase 3

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]

IP6K2 Gene

inositol hexakisphosphate kinase 2

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

IP6K1 Gene

inositol hexakisphosphate kinase 1

This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]

INPP1 Gene

inositol polyphosphate-1-phosphatase

This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008]

IMPAD1 Gene

inositol monophosphatase domain containing 1

This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, Dec 2011]

INPP4B Gene

inositol polyphosphate-4-phosphatase, type II, 105kDa

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]

LOC105370944 Gene

inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1-like

IMPA1P Gene

inositol(myo)-1(or 4)-monophosphatase 1 pseudogene

LOC100421537 Gene

inositol monophosphatase domain containing 1 pseudogene

LOC729654 Gene

inositol polyphosphate multikinase pseudogene

LOC400927 Gene

TPTE and PTEN homologous inositol lipid phosphatase pseudogene

SLC5A3 Gene

solute carrier family 5 (sodium/myo-inositol cotransporter), member 3

ITPKA Gene

inositol-trisphosphate 3-kinase A

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]

ITPKC Gene

inositol-trisphosphate 3-kinase C

This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.[provided by RefSeq, Sep 2009]

ITPKB Gene

inositol-trisphosphate 3-kinase B

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008]

ITPK1 Gene

inositol-tetrakisphosphate 1-kinase

IPPK Gene

inositol 1,3,4,5,6-pentakisphosphate 2-kinase

The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010]

INPP5A Gene

inositol polyphosphate-5-phosphatase, 40kDa

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]

INPP5B Gene

inositol polyphosphate-5-phosphatase, 75kDa

This gene encodes a member of a family of inositol polyphosphate-5-phosphatases. These enzymes function in the regulation of calcium signaling by inactivating inositol phosphates. The encoded protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2014]

INPP5D Gene

inositol polyphosphate-5-phosphatase, 145kDa

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]

INPP5E Gene

inositol polyphosphate-5-phosphatase, 72 kDa

The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly.[provided by RefSeq, Feb 2011]

INPP5F Gene

inositol polyphosphate-5-phosphatase F

The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

INPP5J Gene

inositol polyphosphate-5-phosphatase J

INPP5K Gene

inositol polyphosphate-5-phosphatase K

This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

ITPRIPL2 Gene

inositol 1,4,5-trisphosphate receptor interacting protein-like 2

ITPRIPL1 Gene

inositol 1,4,5-trisphosphate receptor interacting protein-like 1

MINPP1 Gene

multiple inositol-polyphosphate phosphatase 1

This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009]

SLC5A11 Gene

solute carrier family 5 (sodium/inositol cotransporter), member 11

Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008]

LOC645433 Gene

inositol-3-phosphate synthase 1 pseudogene

IPPKP1 Gene

inositol 1,3,4,5,6-pentakisphosphate 2-kinase pseudogene 1

MIOXP1 Gene

myo-inositol oxygenase pseudogene 1

IPMKP1 Gene

inositol polyphosphate multikinase pseudogene 1

IMPA1 Gene

inositol(myo)-1(or 4)-monophosphatase 1

This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Dec 2014]

IMPA2 Gene

inositol(myo)-1(or 4)-monophosphatase 2

This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. [provided by RefSeq, Jan 2011]

INPPL1 Gene

inositol polyphosphate phosphatase-like 1

The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq, Jan 2009]

LOC100421108 Gene

inositol 1,3,4-triphosphate 5/6 kinase pseudogene

ITPR2 Gene

inositol 1,4,5-trisphosphate receptor, type 2

The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]

ITPR3 Gene

inositol 1,4,5-trisphosphate receptor, type 3

This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. [provided by RefSeq, Aug 2010]

ITPR1 Gene

inositol 1,4,5-trisphosphate receptor, type 1

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]

ITPRIP Gene

inositol 1,4,5-trisphosphate receptor interacting protein

This gene encodes a membrane-associated protein that binds the inositol 1,4,5-trisphosphate receptor (ITPR). The encoded protein enhances the sensitivity of ITPR to intracellular calcium signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

MIOX Gene

myo-inositol oxygenase

Inositol-(1,3,4,5,6)-Pentakisphosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the Inositol-(1,3,4,5,6)-Pentakisphosphate drug from the curated DrugBank Drug Targets dataset.

1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate from the curated CTD Gene-Chemical Interactions dataset.

Inositol Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Inositol from the curated CTD Gene-Chemical Interactions dataset.

Inositol Phosphates Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Inositol Phosphates from the curated CTD Gene-Chemical Interactions dataset.

1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical 1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol from the curated CTD Gene-Chemical Interactions dataset.

Inositol 1,4,5-Trisphosphate Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Inositol 1,4,5-Trisphosphate from the curated CTD Gene-Chemical Interactions dataset.

Inositol 1,3,4,5-Tetrakisphosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the Inositol 1,3,4,5-Tetrakisphosphate drug from the curated DrugBank Drug Targets dataset.

Myo-Inositol Gene Set

From DrugBank Drug Targets

interacting proteins for the Myo-Inositol drug from the curated DrugBank Drug Targets dataset.

D-Myo-Inositol-2,4,5-Trisphosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the D-Myo-Inositol-2,4,5-Trisphosphate drug from the curated DrugBank Drug Targets dataset.

L-Myo-Inositol-1-Phosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the L-Myo-Inositol-1-Phosphate drug from the curated DrugBank Drug Targets dataset.

L-Alpha-Glycerophospho-D-Myo-Inositol-4,5-Bis-Phosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the L-Alpha-Glycerophospho-D-Myo-Inositol-4,5-Bis-Phosphate drug from the curated DrugBank Drug Targets dataset.

D-Myo-Inositol-Hexasulphate Gene Set

From DrugBank Drug Targets

interacting proteins for the D-Myo-Inositol-Hexasulphate drug from the curated DrugBank Drug Targets dataset.

D-Myo-Inositol-1,4,5-Triphosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the D-Myo-Inositol-1,4,5-Triphosphate drug from the curated DrugBank Drug Targets dataset.

D-Myo-Inositol-1,4-Bisphosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the D-Myo-Inositol-1,4-Bisphosphate drug from the curated DrugBank Drug Targets dataset.

Inositol 1,3-Bisphosphate Gene Set

From DrugBank Drug Targets

interacting proteins for the Inositol 1,3-Bisphosphate drug from the curated DrugBank Drug Targets dataset.

inositol Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term inositol in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

regulation of inositol-polyphosphate 5-phosphatase activity Gene Set

From GO Biological Process Annotations

genes participating in the regulation of inositol-polyphosphate 5-phosphatase activity biological process from the curated GO Biological Process Annotations dataset.

inositol biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

inositol phosphate biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol phosphate biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of inositol phosphate biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of inositol phosphate biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

inositol phosphate dephosphorylation Gene Set

From GO Biological Process Annotations

genes participating in the inositol phosphate dephosphorylation biological process from the curated GO Biological Process Annotations dataset.

inositol phosphate catabolic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol phosphate catabolic process biological process from the curated GO Biological Process Annotations dataset.

regulation of inositol phosphate biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the regulation of inositol phosphate biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity biological process from the curated GO Biological Process Annotations dataset.

inositol phosphorylation Gene Set

From GO Biological Process Annotations

genes participating in the inositol phosphorylation biological process from the curated GO Biological Process Annotations dataset.

positive regulation of inositol-polyphosphate 5-phosphatase activity Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of inositol-polyphosphate 5-phosphatase activity biological process from the curated GO Biological Process Annotations dataset.

regulation of inositol trisphosphate biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the regulation of inositol trisphosphate biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

positive regulation of inositol trisphosphate biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the positive regulation of inositol trisphosphate biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

myo-inositol transport Gene Set

From GO Biological Process Annotations

genes participating in the myo-inositol transport biological process from the curated GO Biological Process Annotations dataset.

inositol lipid-mediated signaling Gene Set

From GO Biological Process Annotations

genes participating in the inositol lipid-mediated signaling biological process from the curated GO Biological Process Annotations dataset.

inositol phosphate-mediated signaling Gene Set

From GO Biological Process Annotations

genes participating in the inositol phosphate-mediated signaling biological process from the curated GO Biological Process Annotations dataset.

inositol trisphosphate metabolic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol trisphosphate metabolic process biological process from the curated GO Biological Process Annotations dataset.

regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Gene Set

From GO Biological Process Annotations

genes participating in the regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity biological process from the curated GO Biological Process Annotations dataset.

negative regulation of inositol phosphate biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the negative regulation of inositol phosphate biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

inositol phosphate metabolic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol phosphate metabolic process biological process from the curated GO Biological Process Annotations dataset.

inositol catabolic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol catabolic process biological process from the curated GO Biological Process Annotations dataset.

inositol metabolic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol metabolic process biological process from the curated GO Biological Process Annotations dataset.

inositol trisphosphate biosynthetic process Gene Set

From GO Biological Process Annotations

genes participating in the inositol trisphosphate biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol hexakisphosphate 5-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol hexakisphosphate 5-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol monophosphate 1-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol monophosphate 1-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol tetrakisphosphate phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol tetrakisphosphate phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,4,5-trisphosphate 3-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,4,5-trisphosphate 3-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,3,4-trisphosphate 6-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,3,4-trisphosphate 6-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,4,5-trisphosphate 6-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,4,5-trisphosphate 6-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol diphosphate tetrakisphosphate diphosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol diphosphate tetrakisphosphate diphosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol monophosphate phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol monophosphate phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,3,4-trisphosphate 1-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,3,4-trisphosphate 1-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol tetrakisphosphate kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol tetrakisphosphate kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

cdp-diacylglycerol-inositol 3-phosphatidyltransferase activity Gene Set

From GO Molecular Function Annotations

genes performing the cdp-diacylglycerol-inositol 3-phosphatidyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol hexakisphosphate kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol hexakisphosphate kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol tetrakisphosphate 1-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol tetrakisphosphate 1-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-polyphosphate 5-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-polyphosphate 5-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,3,4-trisphosphate 5-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,3,4-trisphosphate 5-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol oxygenase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol oxygenase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol 1,3,4,5 tetrakisphosphate binding Gene Set

From GO Molecular Function Annotations

genes performing the inositol 1,3,4,5 tetrakisphosphate binding molecular function from the curated GO Molecular Function Annotations dataset.

inositol hexakisphosphate 2-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol hexakisphosphate 2-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol trisphosphate kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol trisphosphate kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,4,5-trisphosphate 5-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,4,5-trisphosphate 5-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-hexakisphosphate phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-hexakisphosphate phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-3,4,6-trisphosphate 1-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-3,4,6-trisphosphate 1-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol hexakisphosphate 3-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol hexakisphosphate 3-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol trisphosphate phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol trisphosphate phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-3-phosphate synthase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-3-phosphate synthase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol monophosphate 4-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol monophosphate 4-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol hexakisphosphate 6-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol hexakisphosphate 6-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol hexakisphosphate 1-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol hexakisphosphate 1-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol 1,4,5 trisphosphate binding Gene Set

From GO Molecular Function Annotations

genes performing the inositol 1,4,5 trisphosphate binding molecular function from the curated GO Molecular Function Annotations dataset.

inositol tetrakisphosphate 3-kinase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol tetrakisphosphate 3-kinase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol hexakisphosphate binding Gene Set

From GO Molecular Function Annotations

genes performing the inositol hexakisphosphate binding molecular function from the curated GO Molecular Function Annotations dataset.

inositol bisdiphosphate tetrakisphosphate diphosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol bisdiphosphate tetrakisphosphate diphosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol monophosphate 3-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol monophosphate 3-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,4-bisphosphate 1-phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,4-bisphosphate 1-phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol phosphate phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol phosphate phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol bisphosphate phosphatase activity Gene Set

From GO Molecular Function Annotations

genes performing the inositol bisphosphate phosphatase activity molecular function from the curated GO Molecular Function Annotations dataset.

inositol 2 4 5-trisphosphate Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the inositol 2 4 5-trisphosphate ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

phosphatidyl (3 5) inositol biphosphate Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the phosphatidyl (3 5) inositol biphosphate ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Inositol 1,4,5-trisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Inositol 1,4,5-trisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

1D-Myo-inositol 3,4-bisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1D-Myo-inositol 3,4-bisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

6-(alpha-D-Glucosaminyl)-1D-myo-inositol Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 6-(alpha-D-Glucosaminyl)-1D-myo-inositol metabolite from the curated HMDB Metabolites of Enzymes dataset.

Inositol 1,3,4-trisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Inositol 1,3,4-trisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

1D-Myo-inositol 1,3-bisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1D-Myo-inositol 1,3-bisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

Mannosyl-inositol-phosphorylceramide Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Mannosyl-inositol-phosphorylceramide metabolite from the curated HMDB Metabolites of Enzymes dataset.

1D-Myo-inositol 1,4-bisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1D-Myo-inositol 1,4-bisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

1D-Myo-inositol 1,4,5,6-tetrakisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1D-Myo-inositol 1,4,5,6-tetrakisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

Inositol-P-ceramide Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Inositol-P-ceramide metabolite from the curated HMDB Metabolites of Enzymes dataset.

1-Phosphatidyl-1D-myo-inositol 3-phosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1-Phosphatidyl-1D-myo-inositol 3-phosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

D-Myo-inositol 3,4,5,6-tetrakisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the D-Myo-inositol 3,4,5,6-tetrakisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

Inositol cyclic phosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Inositol cyclic phosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

1-(sn-Glycero-3-phospho)-1D-myo-inositol Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1-(sn-Glycero-3-phospho)-1D-myo-inositol metabolite from the curated HMDB Metabolites of Enzymes dataset.

Inositol phosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Inositol phosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

Inositol 1,3,4,5-tetraphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Inositol 1,3,4,5-tetraphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

1D-Myo-inositol 1,3,4,6-tetrakisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1D-Myo-inositol 1,3,4,6-tetrakisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

1D-myo-Inositol 3-phosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1D-myo-Inositol 3-phosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

Myo-inositol hexakisphosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Myo-inositol hexakisphosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

Myo-inositol 1-phosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Myo-inositol 1-phosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

1-Phosphatidyl-D-myo-inositol Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 1-Phosphatidyl-D-myo-inositol metabolite from the curated HMDB Metabolites of Enzymes dataset.

D-Myo-inositol 4-phosphate Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the D-Myo-inositol 4-phosphate metabolite from the curated HMDB Metabolites of Enzymes dataset.

6-(N-Acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the 6-(N-Acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol metabolite from the curated HMDB Metabolites of Enzymes dataset.

superpathway of inositol phosphate compounds Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of inositol phosphate compounds pathway from the HumanCyc Pathways dataset.

D-myo-inositol-5-phosphate metabolism Gene Set

From HumanCyc Pathways

proteins participating in the D-myo-inositol-5-phosphate metabolism pathway from the HumanCyc Pathways dataset.

D-myo-inositol (1,3,4)-trisphosphate biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the D-myo-inositol (1,3,4)-trisphosphate biosynthesis pathway from the HumanCyc Pathways dataset.

D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis pathway from the HumanCyc Pathways dataset.

D-myo-inositol (1,4,5)-trisphosphate biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the D-myo-inositol (1,4,5)-trisphosphate biosynthesis pathway from the HumanCyc Pathways dataset.

D-myo-inositol (1,4,5)-trisphosphate degradation Gene Set

From HumanCyc Pathways

proteins participating in the D-myo-inositol (1,4,5)-trisphosphate degradation pathway from the HumanCyc Pathways dataset.

1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) Gene Set

From HumanCyc Pathways

proteins participating in the 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) pathway from the HumanCyc Pathways dataset.

1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) Gene Set

From HumanCyc Pathways

proteins participating in the 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) pathway from the HumanCyc Pathways dataset.

myo-inositol de novo biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the myo-inositol de novo biosynthesis pathway from the HumanCyc Pathways dataset.

inositol pyrophosphates biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the inositol pyrophosphates biosynthesis pathway from the HumanCyc Pathways dataset.

D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis pathway from the HumanCyc Pathways dataset.

superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism pathway from the HumanCyc Pathways dataset.

Myo-inositol-1-phosphate synthase, GAPDH-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Myo-inositol-1-phosphate synthase, GAPDH-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol polyphosphate-related phosphatase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol polyphosphate-related phosphatase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol 1,4,5-trisphosphate-binding protein receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol 1,4,5-trisphosphate-binding protein receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol 1,4,5-trisphosphate receptor-interacting protein family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol 1,4,5-trisphosphate receptor-interacting protein family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol monophosphatase, Lithium-sensitive Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol monophosphatase, Lithium-sensitive protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol-tetrakisphosphate 1-kinase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol-tetrakisphosphate 1-kinase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol monophosphatase, metal-binding site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol monophosphatase, metal-binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol oxygenase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol oxygenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol phosphatase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol phosphatase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPI inositol-deacylase PGAP1-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPI inositol-deacylase PGAP1-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol polyphosphate kinase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol polyphosphate kinase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol monophosphatase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol monophosphatase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol monophosphatase, conserved site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol monophosphatase, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol 1,4,5-trisphosphate/ryanodine receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol 1,4,5-trisphosphate/ryanodine receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Sugar/inositol transporter Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sugar/inositol transporter protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Myo-inositol-1-phosphate synthase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Myo-inositol-1-phosphate synthase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Inositol 1,4,5-trisphosphate receptor-interacting protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Inositol 1,4,5-trisphosphate receptor-interacting protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote protein domain from the InterPro Predicted Protein Domain Annotations dataset.

inositol metabolism Gene Set

From KEGG Pathways

proteins participating in the inositol metabolism pathway from the KEGG Pathways dataset.

inositol phosphate metabolism Gene Set

From KEGG Pathways

proteins participating in the inositol phosphate metabolism pathway from the KEGG Pathways dataset.

Inositol transporters Gene Set

From Reactome Pathways

proteins participating in the Inositol transporters pathway from the Reactome Pathways dataset.

Inositol phosphate metabolism Gene Set

From Reactome Pathways

proteins participating in the Inositol phosphate metabolism pathway from the Reactome Pathways dataset.