Name

CTSG Gene

cathepsin G

The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]

ctsg Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ctsg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CTSG Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CTSG from the Pathway Commons Protein-Protein Interactions dataset.

SERPINA3-CTSG complex Gene Set

From CORUM Protein Complexes

proteins in the SERPINA3-CTSG complex protein complex from the CORUM Protein Complexes dataset.

SERPINA1-CTSG complex Gene Set

From CORUM Protein Complexes

proteins in the SERPINA1-CTSG complex protein complex from the CORUM Protein Complexes dataset.