Name

CDK7 Gene

cyclin-dependent kinase 7

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]

CDK7PS Gene

cyclin-dependent kinase 7 pseudogene

cdk7 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdk7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDK7 Gene Set

From KEA Substrates of Kinases

substrates of the kinase CDK7 from the curated KEA Substrates of Kinases dataset.

CDK7 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDK7 from the Pathway Commons Protein-Protein Interactions dataset.

CDK7 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase CDK7 from the curated PhosphoSitePlus Substrates of Kinases dataset.

TFIIH transcription factor complex (ERCC2, ERCC3, GTF2H1, CDK7, CCNH, GTF2H2) Gene Set

From CORUM Protein Complexes

proteins in the TFIIH transcription factor complex (ERCC2, ERCC3, GTF2H1, CDK7, CCNH, GTF2H2) protein complex from the CORUM Protein Complexes dataset.

ESR1-CDK7-CCNH-MNAT1-MTA1-HDAC2 complex Gene Set

From CORUM Protein Complexes

proteins in the ESR1-CDK7-CCNH-MNAT1-MTA1-HDAC2 complex protein complex from the CORUM Protein Complexes dataset.

cdk7dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdk7dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cdk79 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdk79 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDK7_knockdown_124_GSE27869 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the CDK7_knockdown_124_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

CDK7_knockdown_138_GSE31534 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the CDK7_knockdown_138_GSE31534 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

BL1740 (CDK7) Gene Set

From NURSA Protein Complexes

proteins in the BL1740 (CDK7) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL1742 (CDK7) Gene Set

From NURSA Protein Complexes

proteins in the BL1742 (CDK7) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL1743 (CDK7) Gene Set

From NURSA Protein Complexes

proteins in the BL1743 (CDK7) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL1741 (CDK7) Gene Set

From NURSA Protein Complexes

proteins in the BL1741 (CDK7) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.