Name

CDC25A Gene

cell division cycle 25A

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

CDC25A Gene Set

From DEPOD Substrates of Phosphatases

substrates of the phosphatase CDC25A from the curated DEPOD Substrates of Phosphatases dataset.

cdc25a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDC25A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC25A from the Pathway Commons Protein-Protein Interactions dataset.

cdc25acdk2independent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25acdk2independent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL330 (CDC25A) Gene Set

From NURSA Protein Complexes

proteins in the BL330 (CDC25A) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

SC-97 (CDC25A) Gene Set

From NURSA Protein Complexes

proteins in the SC-97 (CDC25A) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set

From Reactome Pathways

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways dataset.