Name

CCDC8 Gene

coiled-coil domain containing 8

This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011]

CCDC88B Gene

coiled-coil domain containing 88B

This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules. [provided by RefSeq, Oct 2009]

CCDC89 Gene

coiled-coil domain containing 89

CCDC83 Gene

coiled-coil domain containing 83

CCDC82 Gene

coiled-coil domain containing 82

CCDC80 Gene

coiled-coil domain containing 80

CCDC87 Gene

coiled-coil domain containing 87

CCDC86 Gene

coiled-coil domain containing 86

CCDC84 Gene

coiled-coil domain containing 84

This gene encodes a protein thought to contain a coiled coil motif. No function has been determined for the encoded protein. A pseudogene of this gene is located on chromosome 20. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

CCDC85C Gene

coiled-coil domain containing 85C

CCDC85B Gene

coiled-coil domain containing 85B

Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro. [provided by RefSeq, Jul 2008]

CCDC85A Gene

coiled-coil domain containing 85A

CCDC88A Gene

coiled-coil domain containing 88A

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

CCDC81 Gene

coiled-coil domain containing 81

CCDC88C Gene

coiled-coil domain containing 88C

This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013]

ccdc8 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ccdc8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CCDC8 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC8 from the Pathway Commons Protein-Protein Interactions dataset.

ccdc88a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ccdc88a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ccdc88c Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ccdc88c in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CCDC85B Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein CCDC85B from the curated Hub Proteins Protein-Protein Interactions dataset.

BL8325 (CCDC86) Gene Set

From NURSA Protein Complexes

proteins in the BL8325 (CCDC86) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL5845 (CCDC82) Gene Set

From NURSA Protein Complexes

proteins in the BL5845 (CCDC82) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

CCDC88C Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for CCDC88C from the NURSA Protein-Protein Interactions dataset.

CCDC86 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC86 from the Pathway Commons Protein-Protein Interactions dataset.

CCDC88B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC88B from the Pathway Commons Protein-Protein Interactions dataset.

CCDC88C Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC88C from the Pathway Commons Protein-Protein Interactions dataset.

CCDC85B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC85B from the Pathway Commons Protein-Protein Interactions dataset.

CCDC85A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC85A from the Pathway Commons Protein-Protein Interactions dataset.

CCDC85C Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC85C from the Pathway Commons Protein-Protein Interactions dataset.

CCDC82 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC82 from the Pathway Commons Protein-Protein Interactions dataset.

CCDC80 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC80 from the Pathway Commons Protein-Protein Interactions dataset.

CCDC87 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC87 from the Pathway Commons Protein-Protein Interactions dataset.

CCDC88A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC88A from the Pathway Commons Protein-Protein Interactions dataset.

CCDC89 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC89 from the Pathway Commons Protein-Protein Interactions dataset.