CCDC50 Gene

coiled-coil domain containing 50

This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

CCDC50 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CCDC50 from the Pathway Commons Protein-Protein Interactions dataset.

BL8315 (CCDC50) Gene Set

From NURSA Protein Complexes

proteins in the BL8315 (CCDC50) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.