SAE2_HUMAN Protein

Name SUMO-activating enzyme subunit 2
Description The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
UniProt ID Q9UBT2
Gene UBA2