NELFE_HUMAN Protein

Name Negative elongation factor E
Description Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.
UniProt ID P18615
Gene NELFE