ALKB4_HUMAN Protein

Name Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4
Description Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.
UniProt ID Q9NXW9
Gene ALKBH4