zymogen activation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The proteolytic processing of an inactive enzyme to an active form. (Gene Ontology, GO_0031638)
External Link http://amigo.geneontology.org/amigo/term/GO:0031638
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Genes

102 genes participating in the zymogen activation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACER2 alkaline ceramidase 2
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APAF1 apoptotic peptidase activating factor 1
APOH apolipoprotein H (beta-2-glycoprotein I)
ASPH aspartate beta-hydroxylase
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BOK BCL2-related ovarian killer
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCK cholecystokinin
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
CIDEB cell death-inducing DFFA-like effector b
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTSH cathepsin H
CUZD1 CUB and zona pellucida-like domains 1
CYCS cytochrome c, somatic
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAP death-associated protein
DHCR24 24-dehydrocholesterol reductase
DIABLO diablo, IAP-binding mitochondrial protein
DLC1 DLC1 Rho GTPase activating protein
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FADD Fas (TNFRSF6)-associated via death domain
FAM162A family with sequence similarity 162, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
GGT1 gamma-glutamyltransferase 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
HIP1 huntingtin interacting protein 1
HIST1H2BA histone cluster 1, H2ba
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IFT57 intraflagellar transport 57
JAK2 Janus kinase 2
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LCK LCK proto-oncogene, Src family tyrosine kinase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK9 mitogen-activated protein kinase 9
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTCH1 mitochondrial carrier 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NKX3-1 NK3 homeobox 1
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PDCD2 programmed cell death 2
PDCD6 programmed cell death 6
PERP PERP, TP53 apoptosis effector
PIDD1 p53-induced death domain protein 1
PLAT plasminogen activator, tissue
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS3 protease, serine, 3
PYCARD PYD and CARD domain containing
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS27L ribosomal protein S27-like
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SENP1 SUMO1/sentrin specific peptidase 1
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TBC1D10A TBC1 domain family, member 10A
TMPRSS9 transmembrane protease, serine 9
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
VCP valosin containing protein
XDH xanthine dehydrogenase