zuclopenthixol-4843 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the zuclopenthixol-4843 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACLY ATP citrate lyase
AHNAK2 AHNAK nucleoprotein 2
AKAP11 A kinase (PRKA) anchor protein 11
APP amyloid beta (A4) precursor protein
AQP3 aquaporin 3 (Gill blood group)
ARTN artemin
ATN1 atrophin 1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BIRC3 baculoviral IAP repeat containing 3
C16ORF45 chromosome 16 open reading frame 45
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CDC25C cell division cycle 25C
CDK20 cyclin-dependent kinase 20
CEMIP cell migration inducing protein, hyaluronan binding
CEP164 centrosomal protein 164kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CGA glycoprotein hormones, alpha polypeptide
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DUSP4 dual specificity phosphatase 4
EAF2 ELL associated factor 2
ERCC4 excision repair cross-complementation group 4
FOXA1 forkhead box A1
FSCN1 fascin actin-bundling protein 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAMT guanidinoacetate N-methyltransferase
GEM GTP binding protein overexpressed in skeletal muscle
GINS4 GINS complex subunit 4 (Sld5 homolog)
GJB3 gap junction protein, beta 3, 31kDa
GLRX glutaredoxin (thioltransferase)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IFI6 interferon, alpha-inducible protein 6
IL1B interleukin 1, beta
IL4R interleukin 4 receptor
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KLF3 Kruppel-like factor 3 (basic)
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LIF leukemia inhibitory factor
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MED18 mediator complex subunit 18
MTCL1 microtubule crosslinking factor 1
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NDRG1 N-myc downstream regulated 1
NEU1 sialidase 1 (lysosomal sialidase)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NFRKB nuclear factor related to kappaB binding protein
NPTX1 neuronal pentraxin I
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHA5 protocadherin alpha 5
PGM3 phosphoglucomutase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCD1 phospholipase C, delta 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLM polymerase (DNA directed), mu
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKCE protein kinase C, epsilon
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
QKI QKI, KH domain containing, RNA binding
RABGAP1 RAB GTPase activating protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNFT1 ring finger protein, transmembrane 1
SEC23A Sec23 homolog A (S. cerevisiae)
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMAD3 SMAD family member 3
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPTBN2 spectrin, beta, non-erythrocytic 2
SQLE squalene epoxidase
SRCAP Snf2-related CREBBP activator protein
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
TMEM242 transmembrane protein 242
TPPP3 tubulin polymerization-promoting protein family member 3
TRIM16 tripartite motif containing 16
TRIM2 tripartite motif containing 2
TRIM23 tripartite motif containing 23
TRIM29 tripartite motif containing 29
TTC33 tetratricopeptide repeat domain 33
ULBP2 UL16 binding protein 2
WIPI1 WD repeat domain, phosphoinositide interacting 1
WNK1 WNK lysine deficient protein kinase 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB22 zinc finger and BTB domain containing 22
ZMYND8 zinc finger, MYND-type containing 8
ZNF609 zinc finger protein 609
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADM adrenomedullin
ANKEF1 ankyrin repeat and EF-hand domain containing 1
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
C1ORF21 chromosome 1 open reading frame 21
C2 complement component 2
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCDC88C coiled-coil domain containing 88C
CEL carboxyl ester lipase
CENPC centromere protein C
CHRM3 cholinergic receptor, muscarinic 3
CRYBG3 beta-gamma crystallin domain containing 3
DUSP9 dual specificity phosphatase 9
EDAR ectodysplasin A receptor
EML4 echinoderm microtubule associated protein like 4
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
FAM186A family with sequence similarity 186, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ21369 uncharacterized protein FLJ21369
FLJ22184
GATA4 GATA binding protein 4
GEMIN8 gem (nuclear organelle) associated protein 8
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HHAT hedgehog acyltransferase
HIST1H2AK histone cluster 1, H2ak
HIST1H2AL histone cluster 1, H2al
HIST1H4D histone cluster 1, H4d
HOXC10 homeobox C10
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0754 KIAA0754
KIF13A kinesin family member 13A
KLF13 Kruppel-like factor 13
KLHL29 kelch-like family member 29
KREMEN2 kringle containing transmembrane protein 2
MRPL52 mitochondrial ribosomal protein L52
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NT5DC3 5'-nucleotidase domain containing 3
OPHN1 oligophrenin 1
OVGP1 oviductal glycoprotein 1, 120kDa
PCDHB8 protocadherin beta 8
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PER3 period circadian clock 3
PMCH pro-melanin-concentrating hormone
PMEL premelanosome protein
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RGS2 regulator of G-protein signaling 2
RLN1 relaxin 1
RNF43 ring finger protein 43
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RUNDC3B RUN domain containing 3B
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SECTM1 secreted and transmembrane 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SNTA1 syntrophin, alpha 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
STON1 stonin 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TIGD6 tigger transposable element derived 6
TM6SF1 transmembrane 6 superfamily member 1
TMEM184C transmembrane protein 184C
TMEM53 transmembrane protein 53
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
VASH2 vasohibin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR91 WD repeat domain 91
ZC3H3 zinc finger CCCH-type containing 3
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF205 zinc finger protein 205
ZNF552 zinc finger protein 552
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747