zomepirac-4479 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the zomepirac-4479 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACTL8 actin-like 8
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADAM7 ADAM metallopeptidase domain 7
ADORA1 adenosine A1 receptor
ARHGAP35 Rho GTPase activating protein 35
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C19ORF73 chromosome 19 open reading frame 73
C3AR1 complement component 3a receptor 1
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD79B CD79b molecule, immunoglobulin-associated beta
CHAD chondroadherin
CNTD2 cyclin N-terminal domain containing 2
CSHL1 chorionic somatomammotropin hormone-like 1
CTSE cathepsin E
DRD2 dopamine receptor D2
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
FLT1 fms-related tyrosine kinase 1
FOXG1 forkhead box G1
FXYD2 FXYD domain containing ion transport regulator 2
GK3P glycerol kinase 3 pseudogene
GLB1L galactosidase, beta 1-like
HCRP1 hepatocellular carcinoma-related HCRP1
HOXD1 homeobox D1
HSF2BP heat shock transcription factor 2 binding protein
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IGL immunoglobulin lambda locus
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
JUND jun D proto-oncogene
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD17 potassium channel tetramerization domain containing 17
KLK12 kallikrein-related peptidase 12
KRT19P2 keratin 19 pseudogene 2
KRTAP9-9 keratin associated protein 9-9
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP7D3 MAP7 domain containing 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MINK1 misshapen-like kinase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYH14 myosin, heavy chain 14, non-muscle
NCALD neurocalcin delta
NCOR2 nuclear receptor corepressor 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEBL nebulette
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NTS neurotensin
OVOL1 ovo-like zinc finger 1
PAPPA2 pappalysin 2
PCP4 Purkinje cell protein 4
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZD7 PDZ domain containing 7
PKDREJ polycystin (PKD) family receptor for egg jelly
PLCB2 phospholipase C, beta 2
POU6F1 POU class 6 homeobox 1
PRDX2 peroxiredoxin 2
PRY PTPN13-like, Y-linked
PTPRR protein tyrosine phosphatase, receptor type, R
QPCT glutaminyl-peptide cyclotransferase
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A5 S100 calcium binding protein A5
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1A sodium channel, voltage gated, type I alpha subunit
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SMAD1 SMAD family member 1
SMAD5-AS1 SMAD5 antisense RNA 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPRR1A small proline-rich protein 1A
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SSX3 synovial sarcoma, X breakpoint 3
ST7L suppression of tumorigenicity 7 like
TAPBPL TAP binding protein-like
TDRD12 tudor domain containing 12
TK2 thymidine kinase 2, mitochondrial
TMEM74B transmembrane protein 74B
TMPRSS15 transmembrane protease, serine 15
TOP3B topoisomerase (DNA) III beta
TRIM3 tripartite motif containing 3
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL3 tubulin tyrosine ligase-like family member 3
ZNF747 zinc finger protein 747
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ANXA10 annexin A10
ARL14 ADP-ribosylation factor-like 14
ARSJ arylsulfatase family, member J
AURKC aurora kinase C
BAG4 BCL2-associated athanogene 4
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C14ORF93 chromosome 14 open reading frame 93
C1ORF112 chromosome 1 open reading frame 112
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
C3 complement component 3
CBX8 chromobox homolog 8
CCNJL cyclin J-like
CFAP69 cilia and flagella associated protein 69
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
COBL cordon-bleu WH2 repeat protein
CXORF56 chromosome X open reading frame 56
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DOLK dolichol kinase
EDIL3 EGF-like repeats and discoidin I-like domains 3
FAM179B family with sequence similarity 179, member B
FLJ10038 uncharacterized protein FLJ10038
GAS8 growth arrest-specific 8
GJC1 gap junction protein, gamma 1, 45kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH3 G patch domain containing 3
GRAMD4 GRAM domain containing 4
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIST1H3G histone cluster 1, H3g
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFI6 interferon, alpha-inducible protein 6
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IQCG IQ motif containing G
KDM4D lysine (K)-specific demethylase 4D
KIRREL kin of IRRE like (Drosophila)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MAP1S microtubule-associated protein 1S
MDFI MyoD family inhibitor
MED4 mediator complex subunit 4
MFSD11 major facilitator superfamily domain containing 11
MGC12488
MGMT O-6-methylguanine-DNA methyltransferase
MRPL44 mitochondrial ribosomal protein L44
MUC3A mucin 3A, cell surface associated
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX1 MX dynamin-like GTPase 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NMB neuromedin B
NT5C 5', 3'-nucleotidase, cytosolic
NUBP2 nucleotide binding protein 2
NUP62CL nucleoporin 62kDa C-terminal like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGPEP1 pyroglutamyl-peptidase I
PHEX phosphate regulating endopeptidase homolog, X-linked
PLA2G15 phospholipase A2, group XV
POLL polymerase (DNA directed), lambda
PORCN porcupine homolog (Drosophila)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR14L proline rich 14-like
SDC3 syndecan 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D19 TBC1 domain family, member 19
TGS1 trimethylguanosine synthase 1
THRAP3 thyroid hormone receptor associated protein 3
TM7SF2 transmembrane 7 superfamily member 2
TMEM120B transmembrane protein 120B
TMEM53 transmembrane protein 53
TPST2 tyrosylprotein sulfotransferase 2
TSPAN1 tetraspanin 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP18 ubiquitin specific peptidase 18
VASH2 vasohibin 2
WWC2 WW and C2 domain containing 2
ZBTB6 zinc finger and BTB domain containing 6
ZNF124 zinc finger protein 124
ZNF358 zinc finger protein 358
ZNF623 zinc finger protein 623
ZNF778 zinc finger protein 778