zomepirac-2713 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the zomepirac-2713 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABLIM1 actin binding LIM protein 1
ACAN aggrecan
ADGRB1 adhesion G protein-coupled receptor B1
ADRA2B adrenoceptor alpha 2B
AMOTL2 angiomotin like 2
APOE apolipoprotein E
ATG10 autophagy related 10
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BEGAIN brain-enriched guanylate kinase-associated
BIN1 bridging integrator 1
BTN3A1 butyrophilin, subfamily 3, member A1
C17ORF59 chromosome 17 open reading frame 59
CCDC181 coiled-coil domain containing 181
CCDC40 coiled-coil domain containing 40
CCKAR cholecystokinin A receptor
CDCP1 CUB domain containing protein 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP250 centrosomal protein 250kDa
CHIA chitinase, acidic
CIITA class II, major histocompatibility complex, transactivator
CLCN4 chloride channel, voltage-sensitive 4
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNR1 cannabinoid receptor 1 (brain)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMWD dystrophia myotonica, WD repeat containing
DST dystonin
EDDM3A epididymal protein 3A
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPS8L1 EPS8-like 1
EXTL3 exostosin-like glycosyltransferase 3
FLRT1 fibronectin leucine rich transmembrane protein 1
FOSL2 FOS-like antigen 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GFER growth factor, augmenter of liver regeneration
GPM6B glycoprotein M6B
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSN gelsolin
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H4E histone cluster 1, H4e
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGL immunoglobulin lambda locus
IL11 interleukin 11
IL3RA interleukin 3 receptor, alpha (low affinity)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPK1 inositol-tetrakisphosphate 1-kinase
KIF5C kinesin family member 5C
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF6 Kruppel-like factor 6
KLHL35 kelch-like family member 35
KRT8P12 keratin 8 pseudogene 12
LCAT lecithin-cholesterol acyltransferase
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LOC390998 ribosomal protein L10 pseudogene
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEA8 melanoma antigen family A8
MAL mal, T-cell differentiation protein
MAPT microtubule-associated protein tau
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP188 nucleoporin 188kDa
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE4D phosphodiesterase 4D, cAMP-specific
PICK1 protein interacting with PRKCA 1
PLK4 polo-like kinase 4
PPT2 palmitoyl-protein thioesterase 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRH protein tyrosine phosphatase, receptor type, H
PYHIN1 pyrin and HIN domain family, member 1
RAD51B RAD51 paralog B
RANBP3 RAN binding protein 3
RNF126P1 ring finger protein 126 pseudogene 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAA4 serum amyloid A4, constitutive
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIX2 SIX homeobox 2
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SOX12 SRY (sex determining region Y)-box 12
SOX30 SRY (sex determining region Y)-box 30
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SYNM synemin, intermediate filament protein
TBXAS1 thromboxane A synthase 1 (platelet)
TCP10 t-complex 10
TMEM140 transmembrane protein 140
TRIL TLR4 interactor with leucine-rich repeats
TSPAN9 tetraspanin 9
TTC30A tetratricopeptide repeat domain 30A
VPS9D1 VPS9 domain containing 1
WDR55 WD repeat domain 55
ZNF205 zinc finger protein 205
ZNF259P1 zinc finger protein 259 pseudogene 1

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMT aminomethyltransferase
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASCC1 activating signal cointegrator 1 complex subunit 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHCC1 BAH domain and coiled-coil containing 1
BBS7 Bardet-Biedl syndrome 7
C19ORF40 chromosome 19 open reading frame 40
C1ORF109 chromosome 1 open reading frame 109
CAMKMT calmodulin-lysine N-methyltransferase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CCDC85C coiled-coil domain containing 85C
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CDR2L cerebellar degeneration-related protein 2-like
CLIP2 CAP-GLY domain containing linker protein 2
CRYGC crystallin, gamma C
CYSLTR1 cysteinyl leukotriene receptor 1
DENND5B DENN/MADD domain containing 5B
DYSF dysferlin
ELAC1 elaC ribonuclease Z 1
EMD emerin
ENO3 enolase 3 (beta, muscle)
ETV4 ets variant 4
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF23 fibroblast growth factor 23
FKBP5 FK506 binding protein 5
GIPC1 GIPC PDZ domain containing family, member 1
GSTT1 glutathione S-transferase theta 1
HDAC5 histone deacetylase 5
HIST1H2AE histone cluster 1, H2ae
HIST1H2AG histone cluster 1, H2ag
HMG20A high mobility group 20A
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPA1L heat shock 70kDa protein 1-like
IFNA14 interferon, alpha 14
IQSEC1 IQ motif and Sec7 domain 1
IREB2 iron-responsive element binding protein 2
JUP junction plakoglobin
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF13B kinesin family member 13B
KLHL28 kelch-like family member 28
LTC4S leukotriene C4 synthase
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MFSD11 major facilitator superfamily domain containing 11
MYOZ3 myozenin 3
NCALD neurocalcin delta
NCS1 neuronal calcium sensor 1
NNAT neuronatin
NTSR1 neurotensin receptor 1 (high affinity)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLAH oleoyl-ACP hydrolase
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCYOX1 prenylcysteine oxidase 1
PENK proenkephalin
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLS1 plastin 1
PRKCZ protein kinase C, zeta
RAB3A RAB3A, member RAS oncogene family
RCAN3 RCAN family member 3
REC8 REC8 meiotic recombination protein
RHBDD3 rhomboid domain containing 3
RSF1 remodeling and spacing factor 1
SIN3B SIN3 transcription regulator family member B
SIRT6 sirtuin 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SPATA1 spermatogenesis associated 1
STAT5A signal transducer and activator of transcription 5A
SV2A synaptic vesicle glycoprotein 2A
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
TIGD6 tigger transposable element derived 6
TMEM110 transmembrane protein 110
TRAPPC13 trafficking protein particle complex 13
UPB1 ureidopropionase, beta
VASH2 vasohibin 2
VN1R1 vomeronasal 1 receptor 1
WDR33 WD repeat domain 33
YY2 YY2 transcription factor
ZNF276 zinc finger protein 276
ZNF329 zinc finger protein 329
ZNF43 zinc finger protein 43