zidovudine-6733 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the zidovudine-6733 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACVR1B activin A receptor, type IB
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKRD12 ankyrin repeat domain 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
AURKA aurora kinase A
BBC3 BCL2 binding component 3
BMP8B bone morphogenetic protein 8b
BTG2 BTG family, member 2
C11ORF30 chromosome 11 open reading frame 30
C3 complement component 3
C9ORF156 chromosome 9 open reading frame 156
CD58 CD58 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL5A1 collagen, type V, alpha 1
CXCR4 chemokine (C-X-C motif) receptor 4
DBR1 debranching RNA lariats 1
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EIF5B eukaryotic translation initiation factor 5B
ELOVL5 ELOVL fatty acid elongase 5
ERAP1 endoplasmic reticulum aminopeptidase 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZR ezrin
FGFR2 fibroblast growth factor receptor 2
FLOT1 flotillin 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GPR21 G protein-coupled receptor 21
GRIK5 glutamate receptor, ionotropic, kainate 5
GRSF1 G-rich RNA sequence binding factor 1
GUK1 guanylate kinase 1
HIPK3 homeodomain interacting protein kinase 3
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HPS1 Hermansky-Pudlak syndrome 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IER3IP1 immediate early response 3 interacting protein 1
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
ING4 inhibitor of growth family, member 4
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA1467 KIAA1467
KIDINS220 kinase D-interacting substrate, 220kDa
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMC2 laminin, gamma 2
LIPG lipase, endothelial
MAP7D3 MAP7 domain containing 3
MAX MYC associated factor X
MFAP3L microfibrillar-associated protein 3-like
NCKAP1 NCK-associated protein 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NNAT neuronatin
NNT nicotinamide nucleotide transhydrogenase
NOD1 nucleotide-binding oligomerization domain containing 1
NPC1 Niemann-Pick disease, type C1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OAZ3 ornithine decarboxylase antizyme 3
PDE10A phosphodiesterase 10A
PDGFA platelet-derived growth factor alpha polypeptide
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGK1 phosphoglycerate kinase 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMCH pro-melanin-concentrating hormone
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTCRA pre T-cell antigen receptor alpha
PTK7 protein tyrosine kinase 7 (inactive)
RAB2A RAB2A, member RAS oncogene family
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPAIN RPA interacting protein
RXRB retinoid X receptor, beta
SAP30 Sin3A-associated protein, 30kDa
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
TBXA2R thromboxane A2 receptor
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THRAP3 thyroid hormone receptor associated protein 3
TM6SF1 transmembrane 6 superfamily member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAM1 translocation associated membrane protein 1
TWF1 twinfilin actin binding protein 1
TXN thioredoxin
UPK1B uroplakin 1B
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
WSB1 WD repeat and SOCS box containing 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YIPF4 Yip1 domain family, member 4

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
AFAP1 actin filament associated protein 1
AHDC1 AT hook, DNA binding motif, containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
APOC4 apolipoprotein C-IV
ARRB2 arrestin, beta 2
ATG2A autophagy related 2A
AXIN1 axin 1
C7ORF69 chromosome 7 open reading frame 69
CAPN15 calpain 15
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHMP6 charged multivesicular body protein 6
CIDEB cell death-inducing DFFA-like effector b
CORO1A coronin, actin binding protein, 1A
DCSTAMP dendrocyte expressed seven transmembrane protein
DNM1 dynamin 1
DNM3 dynamin 3
ECM1 extracellular matrix protein 1
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FAM120C family with sequence similarity 120C
FAM188A family with sequence similarity 188, member A
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSD1 fibronectin type III and SPRY domain containing 1
GMPR guanosine monophosphate reductase
GPC3 glypican 3
GRM4 glutamate receptor, metabotropic 4
HDAC11 histone deacetylase 11
HESX1 HESX homeobox 1
HIST1H1D histone cluster 1, H1d
HIST1H2BN histone cluster 1, H2bn
HOXC4 homeobox C4
HSPB6 heat shock protein, alpha-crystallin-related, B6
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIRREL kin of IRRE like (Drosophila)
KLHL36 kelch-like family member 36
LIME1 Lck interacting transmembrane adaptor 1
LPAR4 lysophosphatidic acid receptor 4
MAP3K7CL MAP3K7 C-terminal like
MAPK12 mitogen-activated protein kinase 12
MBL1P mannose-binding lectin (protein A) 1, pseudogene
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MICU1 mitochondrial calcium uptake 1
MTERF4 mitochondrial transcription termination factor 4
MYL9 myosin, light chain 9, regulatory
NEK11 NIMA-related kinase 11
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PCDH12 protocadherin 12
PDZK1 PDZ domain containing 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POLL polymerase (DNA directed), lambda
PRF1 perforin 1 (pore forming protein)
PRICKLE3 prickle homolog 3 (Drosophila)
PRR7 proline rich 7 (synaptic)
PSRC1 proline/serine-rich coiled-coil 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGCC regulator of cell cycle
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SBNO2 strawberry notch homolog 2 (Drosophila)
SCEL sciellin
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SPATA1 spermatogenesis associated 1
STARD3 StAR-related lipid transfer (START) domain containing 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNS2 tensin 2
TRIM25 tripartite motif containing 25
TROAP trophinin associated protein
UBTD1 ubiquitin domain containing 1
VWA1 von Willebrand factor A domain containing 1
WNT1 wingless-type MMTV integration site family, member 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZFHX3 zinc finger homeobox 3
ZNF580 zinc finger protein 580
ZNF721 zinc finger protein 721
ZNF862 zinc finger protein 862
ZXDB zinc finger, X-linked, duplicated B
ZYX zyxin