zardaverine-7347 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the zardaverine-7347 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
ADCY1 adenylate cyclase 1 (brain)
ADGRE5 adhesion G protein-coupled receptor E5
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AMH anti-Mullerian hormone
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BMP5 bone morphogenetic protein 5
C1ORF61 chromosome 1 open reading frame 61
C8ORF60 chromosome 8 open reading frame 60
CCDC186 coiled-coil domain containing 186
CCDC64 coiled-coil domain containing 64
CCP110 centriolar coiled coil protein 110kDa
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CSF1 colony stimulating factor 1 (macrophage)
CXCR4 chemokine (C-X-C motif) receptor 4
CYHR1 cysteine/histidine-rich 1
DAPK2 death-associated protein kinase 2
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DFNB31 deafness, autosomal recessive 31
DGCR2 DiGeorge syndrome critical region gene 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIO2 deiodinase, iodothyronine, type II
DRD2 dopamine receptor D2
DUSP2 dual specificity phosphatase 2
EFNA3 ephrin-A3
EML3 echinoderm microtubule associated protein like 3
EPHA1 EPH receptor A1
EPHB2 EPH receptor B2
EPOR erythropoietin receptor
ERCC2 excision repair cross-complementation group 2
EXO5 exonuclease 5
FAM169A family with sequence similarity 169, member A
FAM63B family with sequence similarity 63, member B
FBXO11 F-box protein 11
FBXO2 F-box protein 2
FGFR4 fibroblast growth factor receptor 4
GLP1R glucagon-like peptide 1 receptor
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR137 G protein-coupled receptor 137
GPR4 G protein-coupled receptor 4
HHAT hedgehog acyltransferase
HOMER3 homer scaffolding protein 3
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRS2 insulin receptor substrate 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT19P2 keratin 19 pseudogene 2
LMBR1L limb development membrane protein 1-like
LONP2 lon peptidase 2, peroxisomal
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MALT1 MALT1 paracaspase
MARK2 MAP/microtubule affinity-regulating kinase 2
MEIS1 Meis homeobox 1
MTA2 metastasis associated 1 family, member 2
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYOF myoferlin
MZF1 myeloid zinc finger 1
NAIP NLR family, apoptosis inhibitory protein
NCAPH2 non-SMC condensin II complex, subunit H2
NDRG2 NDRG family member 2
NF1 neurofibromin 1
NMT2 N-myristoyltransferase 2
NPPB natriuretic peptide B
NPY2R neuropeptide Y receptor Y2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARD6A par-6 family cell polarity regulator alpha
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHF20 PHD finger protein 20
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLIN2 perilipin 2
PLK3 polo-like kinase 3
RARA retinoic acid receptor, alpha
RBM19 RNA binding motif protein 19
RHOBTB2 Rho-related BTB domain containing 2
RNF208 ring finger protein 208
SAP30 Sin3A-associated protein, 30kDa
SBF1 SET binding factor 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIM1 single-minded family bHLH transcription factor 1
SKAP1 src kinase associated phosphoprotein 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SYNPO synaptopodin
TBC1D30 TBC1 domain family, member 30
TDRKH tudor and KH domain containing
TM4SF1 transmembrane 4 L six family member 1
TMCO3 transmembrane and coiled-coil domains 3
TMEM212 transmembrane protein 212
TRIM10 tripartite motif containing 10
TRIM45 tripartite motif containing 45
TSGA10 testis specific, 10
TTC9 tetratricopeptide repeat domain 9
TWF1 twinfilin actin binding protein 1
USP20 ubiquitin specific peptidase 20
WDFY3 WD repeat and FYVE domain containing 3
WSCD1 WSC domain containing 1
ZER1 zyg-11 related, cell cycle regulator
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AES amino-terminal enhancer of split
AKAP12 A kinase (PRKA) anchor protein 12
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOD apolipoprotein D
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL15 ADP-ribosylation factor-like 15
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BMP4 bone morphogenetic protein 4
C19ORF40 chromosome 19 open reading frame 40
CIR1 corepressor interacting with RBPJ, 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRBN cereblon
CRYBG3 beta-gamma crystallin domain containing 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DEAF1 DEAF1 transcription factor
DNALI1 dynein, axonemal, light intermediate chain 1
DRD1 dopamine receptor D1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EVPL envoplakin
FAAH fatty acid amide hydrolase
FBRS fibrosin
GBP2 guanylate binding protein 2, interferon-inducible
GLS2 glutaminase 2 (liver, mitochondrial)
GNL1 guanine nucleotide binding protein-like 1
GRB7 growth factor receptor-bound protein 7
HIST1H2AI histone cluster 1, H2ai
HIST2H2AA3 histone cluster 2, H2aa3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC13 homeobox C13
IFI6 interferon, alpha-inducible protein 6
IGFLR1 IGF-like family receptor 1
INCENP inner centromere protein antigens 135/155kDa
IPO13 importin 13
IRF6 interferon regulatory factor 6
ITPKB inositol-trisphosphate 3-kinase B
JUNB jun B proto-oncogene
KIAA0556 KIAA0556
KIF13B kinesin family member 13B
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL25 kelch-like family member 25
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC100287590 uncharacterized LOC100287590
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MCOLN3 mucolipin 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NES nestin
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY5R neuropeptide Y receptor Y5
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCDHB8 protocadherin beta 8
PLD3 phospholipase D family, member 3
PODXL2 podocalyxin-like 2
PRPH peripherin
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RECQL4 RecQ protein-like 4
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A8 solute carrier family 12, member 8
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THBS3 thrombospondin 3
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TSSC4 tumor suppressing subtransferable candidate 4
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
USP6NL USP6 N-terminal like
WDR25 WD repeat domain 25
WDR91 WD repeat domain 91
ZMAT5 zinc finger, matrin-type 5
ZNF16 zinc finger protein 16
ZNF227 zinc finger protein 227
ZNF623 zinc finger protein 623
ZNF654 zinc finger protein 654
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862