zardaverine-4793 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the zardaverine-4793 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM10 ADAM metallopeptidase domain 10
ANGEL2 angel homolog 2 (Drosophila)
APOE apolipoprotein E
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP1 Rho GTPase activating protein 1
ATM ATM serine/threonine kinase
B9D1 B9 protein domain 1
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C6ORF62 chromosome 6 open reading frame 62
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPRIN1 cell cycle associated protein 1
CBR4 carbonyl reductase 4
CCNG2 cyclin G2
CD72 CD72 molecule
CDC14A cell division cycle 14A
COMMD4 COMM domain containing 4
CXORF21 chromosome X open reading frame 21
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCT dopachrome tautomerase
EFS embryonal Fyn-associated substrate
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EPHA1 EPH receptor A1
ERN1 endoplasmic reticulum to nucleus signaling 1
EXOC5 exocyst complex component 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FGF13 fibroblast growth factor 13
FH fumarate hydratase
FRMD1 FERM domain containing 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GBP1 guanylate binding protein 1, interferon-inducible
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA6 homeobox A6
IPO8 importin 8
ITGA10 integrin, alpha 10
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM5B lysine (K)-specific demethylase 5B
KLK13 kallikrein-related peptidase 13
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAN1A2 mannosidase, alpha, class 1A, member 2
MAN2A2 mannosidase, alpha, class 2A, member 2
MCF2L MCF.2 cell line derived transforming sequence-like
MCL1 myeloid cell leukemia 1
MCM3AP minichromosome maintenance complex component 3 associated protein
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MSH6 mutS homolog 6
MTRF1L mitochondrial translational release factor 1-like
NR4A1 nuclear receptor subfamily 4, group A, member 1
PAPOLA poly(A) polymerase alpha
PARD6B par-6 family cell polarity regulator beta
PEX11A peroxisomal biogenesis factor 11 alpha
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G1B phospholipase A2, group IB (pancreas)
PRB3 proline-rich protein BstNI subfamily 3
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB11B RAB11B, member RAS oncogene family
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RBBP9 retinoblastoma binding protein 9
RFC3 replication factor C (activator 1) 3, 38kDa
RGS14 regulator of G-protein signaling 14
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCAND2P SCAN domain containing 2 pseudogene
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCYL2 SCY1-like 2 (S. cerevisiae)
SGPP1 sphingosine-1-phosphate phosphatase 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMAD5 SMAD family member 5
SOS2 son of sevenless homolog 2 (Drosophila)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQLE squalene epoxidase
SRPK2 SRSF protein kinase 2
SSBP2 single-stranded DNA binding protein 2
STAB2 stabilin 2
SUGP1 SURP and G patch domain containing 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPMT thiopurine S-methyltransferase
TROVE2 TROVE domain family, member 2
TRPC3 transient receptor potential cation channel, subfamily C, member 3
VAMP5 vesicle-associated membrane protein 5
WDFY3 WD repeat and FYVE domain containing 3
XYLB xylulokinase homolog (H. influenzae)
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ADCY7 adenylate cyclase 7
AHDC1 AT hook, DNA binding motif, containing 1
ANAPC2 anaphase promoting complex subunit 2
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID3A AT rich interactive domain 3A (BRIGHT-like)
AXIN1 axin 1
BFSP1 beaded filament structural protein 1, filensin
BRPF1 bromodomain and PHD finger containing, 1
BTD biotinidase
C19ORF40 chromosome 19 open reading frame 40
C5ORF45 chromosome 5 open reading frame 45
CAPN15 calpain 15
CCDC186 coiled-coil domain containing 186
CCNL2 cyclin L2
CDK3 cyclin-dependent kinase 3
CIC capicua transcriptional repressor
CNN2 calponin 2
CUEDC1 CUE domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DYSF dysferlin
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM110B family with sequence similarity 110, member B
FAM155B family with sequence similarity 155, member B
FAM63A family with sequence similarity 63, member A
FBXO31 F-box protein 31
FHOD1 formin homology 2 domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPPL1 inositol polyphosphate phosphatase-like 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD7 potassium channel tetramerization domain containing 7
KIAA0894 KIAA0894 protein
KLHL26 kelch-like family member 26
LHX1 LIM homeobox 1
LIF leukemia inhibitory factor
LIN7B lin-7 homolog B (C. elegans)
MED24 mediator complex subunit 24
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MUC3B mucin 3B, cell surface associated
NDRG1 N-myc downstream regulated 1
NEUROD4 neuronal differentiation 4
NKX3-2 NK3 homeobox 2
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMF1 polyamine-modulated factor 1
PODXL2 podocalyxin-like 2
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRU protein tyrosine phosphatase, receptor type, U
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL23AP32 ribosomal protein L23a pseudogene 32
RUFY2 RUN and FYVE domain containing 2
SDC3 syndecan 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2D4A SH2 domain containing 4A
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TBC1D10B TBC1 domain family, member 10B
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM121 transmembrane protein 121
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM25 tripartite motif containing 25
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3C tubulin, alpha 3c
TXLNA taxilin alpha
UNC119 unc-119 homolog (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VEGFB vascular endothelial growth factor B
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR18 WD repeat domain 18
WDR19 WD repeat domain 19
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF324 zinc finger protein 324
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747