zalcitabine-4799 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the zalcitabine-4799 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C17ORF80 chromosome 17 open reading frame 80
C1ORF56 chromosome 1 open reading frame 56
C6ORF62 chromosome 6 open reading frame 62
CAPN7 calpain 7
CAPRIN1 cell cycle associated protein 1
CASD1 CAS1 domain containing 1
CHD1L chromodomain helicase DNA binding protein 1-like
CLDND1 claudin domain containing 1
DBF4B DBF4 zinc finger B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEGS1 delta(4)-desaturase, sphingolipid 1
DIEXF digestive organ expansion factor homolog (zebrafish)
DPY19L1P1 DPY19L1 pseudogene 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EXOC5 exocyst complex component 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FH fumarate hydratase
FRS2 fibroblast growth factor receptor substrate 2
GBAS glioblastoma amplified sequence
GLIPR1 GLI pathogenesis-related 1
GPM6B glycoprotein M6B
GULP1 GULP, engulfment adaptor PTB domain containing 1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRF4 interferon regulatory factor 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD20 potassium channel tetramerization domain containing 20
KRIT1 KRIT1, ankyrin repeat containing
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCF2L MCF.2 cell line derived transforming sequence-like
MCL1 myeloid cell leukemia 1
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTMR2 myotubularin related protein 2
NCKAP1 NCK-associated protein 1
NFX1 nuclear transcription factor, X-box binding 1
NNT nicotinamide nucleotide transhydrogenase
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR2E3 nuclear receptor subfamily 2, group E, member 3
NXT2 nuclear transport factor 2-like export factor 2
OSMR oncostatin M receptor
PARD6B par-6 family cell polarity regulator beta
PICALM phosphatidylinositol binding clathrin assembly protein
POFUT1 protein O-fucosyltransferase 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRPF4B pre-mRNA processing factor 4B
PUM1 pumilio RNA-binding family member 1
RAB1A RAB1A, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD51 RAD51 recombinase
RALB v-ral simian leukemia viral oncogene homolog B
RNF146 ring finger protein 146
RNFT1 ring finger protein, transmembrane 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCAMP1 secretory carrier membrane protein 1
SCG2 secretogranin II
SCYL2 SCY1-like 2 (S. cerevisiae)
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC17A2 solute carrier family 17, member 2
SLC35F5 solute carrier family 35, member F5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMAD5 SMAD family member 5
SOAT1 sterol O-acyltransferase 1
SQLE squalene epoxidase
ST7 suppression of tumorigenicity 7
STK3 serine/threonine kinase 3
SYNJ1 synaptojanin 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFDP1 transcription factor Dp-1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM212 transmembrane protein 212
TOR1AIP1 torsin A interacting protein 1
TRAM1 translocation associated membrane protein 1
TRIM23 tripartite motif containing 23
TRIM36 tripartite motif containing 36
TSC22D3 TSC22 domain family, member 3
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAMP3 vesicle-associated membrane protein 3
VAMP4 vesicle-associated membrane protein 4
VWA5A von Willebrand factor A domain containing 5A
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ABLIM3 actin binding LIM protein family, member 3
ADCY6 adenylate cyclase 6
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMDHD2 amidohydrolase domain containing 2
AMPD2 adenosine monophosphate deaminase 2
APOC4 apolipoprotein C-IV
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C17ORF70 chromosome 17 open reading frame 70
C1ORF35 chromosome 1 open reading frame 35
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF54 chromosome 2 open reading frame 54
C5AR2 complement component 5a receptor 2
CA11 carbonic anhydrase XI
CCDC85C coiled-coil domain containing 85C
CCDC94 coiled-coil domain containing 94
CCNO cyclin O
CDK3 cyclin-dependent kinase 3
CFAP44 cilia and flagella associated protein 44
CISH cytokine inducible SH2-containing protein
CORO1A coronin, actin binding protein, 1A
CORO7 coronin 7
CPED1 cadherin-like and PC-esterase domain containing 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRABP1 cellular retinoic acid binding protein 1
CRIP1 cysteine-rich protein 1 (intestinal)
CTNNBIP1 catenin, beta interacting protein 1
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
ECSIT ECSIT signalling integrator
EGFL7 EGF-like-domain, multiple 7
FBXO2 F-box protein 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPC3 glypican 3
GRB7 growth factor receptor-bound protein 7
GSTT1 glutathione S-transferase theta 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HHLA3 HERV-H LTR-associating 3
HMOX1 heme oxygenase 1
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KRT31 keratin 31, type I
LAMA3 laminin, alpha 3
LAMP3 lysosomal-associated membrane protein 3
LMCD1 LIM and cysteine-rich domains 1
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC8E leucine rich repeat containing 8 family, member E
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MTERF4 mitochondrial transcription termination factor 4
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPFFR1 neuropeptide FF receptor 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRTN neurturin
NYNRIN NYN domain and retroviral integrase containing
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHB3 protocadherin beta 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PILRB paired immunoglobin-like type 2 receptor beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLXNA3 plexin A3
PMEL premelanosome protein
PTGES2 prostaglandin E synthase 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRU protein tyrosine phosphatase, receptor type, U
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RECQL4 RecQ protein-like 4
RNF220 ring finger protein 220
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SPINK5 serine peptidase inhibitor, Kazal type 5
THAP7 THAP domain containing 7
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRMT61A tRNA methyltransferase 61A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
ZBED1 zinc finger, BED-type containing 1
ZC3H3 zinc finger CCCH-type containing 3
ZFHX3 zinc finger homeobox 3
ZNF205 zinc finger protein 205
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787