yohimbic acid-4082 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the yohimbic acid-4082 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADAM28 ADAM metallopeptidase domain 28
ADCK2 aarF domain containing kinase 2
ADGRB2 adhesion G protein-coupled receptor B2
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BTBD18 BTB (POZ) domain containing 18
C11ORF16 chromosome 11 open reading frame 16
C1S complement component 1, s subcomponent
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD200 CD200 molecule
CEP41 centrosomal protein 41kDa
CLCN4 chloride channel, voltage-sensitive 4
CNTN1 contactin 1
COL16A1 collagen, type XVI, alpha 1
COL1A1 collagen, type I, alpha 1
COL21A1 collagen, type XXI, alpha 1
CTNS cystinosin, lysosomal cystine transporter
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF11 DDB1 and CUL4 associated factor 11
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNASE2B deoxyribonuclease II beta
DPF1 D4, zinc and double PHD fingers family 1
EFR3B EFR3 homolog B (S. cerevisiae)
EMC3 ER membrane protein complex subunit 3
ESRRG estrogen-related receptor gamma
ETV6 ets variant 6
F13A1 coagulation factor XIII, A1 polypeptide
FCAR Fc fragment of IgA receptor
FGF9 fibroblast growth factor 9
FKSG49 FKSG49
FRZB frizzled-related protein
FSCN3 fascin actin-bundling protein 3, testicular
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLB1L galactosidase, beta 1-like
GOLGA8A golgin A8 family, member A
GPR1 G protein-coupled receptor 1
GPR22 G protein-coupled receptor 22
HFE hemochromatosis
HSF1 heat shock transcription factor 1
IDI2-AS1 IDI2 antisense RNA 1
IL1RN interleukin 1 receptor antagonist
INE1 inactivation escape 1 (non-protein coding)
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF13A kinesin family member 13A
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LOC100294391 uncharacterized LOC100294391
LPIN1 lipin 1
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEB2 melanoma antigen family B2
MAPK11 mitogen-activated protein kinase 11
MCF2L MCF.2 cell line derived transforming sequence-like
MOBP myelin-associated oligodendrocyte basic protein
MST1 macrophage stimulating 1
NAV3 neuron navigator 3
NF1 neurofibromin 1
NPC1 Niemann-Pick disease, type C1
NPIPB3 nuclear pore complex interacting protein family, member B3
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PKP4 plakophilin 4
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLK4 polo-like kinase 4
RBMS3 RNA binding motif, single stranded interacting protein 3
RET ret proto-oncogene
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SARM1 sterile alpha and TIR motif containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SCD5 stearoyl-CoA desaturase 5
SCN11A sodium channel, voltage gated, type XI alpha subunit
SH3GL3 SH3-domain GRB2-like 3
SLAMF8 SLAM family member 8
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLMO1 slowmo homolog 1 (Drosophila)
SMO smoothened, frizzled class receptor
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPPL2B signal peptide peptidase like 2B
STAB1 stabilin 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBC1D2B TBC1 domain family, member 2B
TBX6 T-box 6
TGM4 transglutaminase 4
TNIK TRAF2 and NCK interacting kinase
TNS1 tensin 1
TSC2 tuberous sclerosis 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
USP29 ubiquitin specific peptidase 29
UST uronyl-2-sulfotransferase
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ADAM2 ADAM metallopeptidase domain 2
APOL6 apolipoprotein L, 6
ARHGAP24 Rho GTPase activating protein 24
ARR3 arrestin 3, retinal (X-arrestin)
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAGE B melanoma antigen
BDKRB1 bradykinin receptor B1
BFSP1 beaded filament structural protein 1, filensin
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF80 chromosome 11 open reading frame 80
CA11 carbonic anhydrase XI
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CD68 CD68 molecule
CDON cell adhesion associated, oncogene regulated
CFAP45 cilia and flagella associated protein 45
CGA glycoprotein hormones, alpha polypeptide
CGREF1 cell growth regulator with EF-hand domain 1
CHRDL1 chordin-like 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXORF21 chromosome X open reading frame 21
CYB5R2 cytochrome b5 reductase 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DNAH17 dynein, axonemal, heavy chain 17
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAL4 dynein, axonemal, light chain 4
DPYS dihydropyrimidinase
DSPP dentin sialophosphoprotein
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM120C family with sequence similarity 120C
FGF23 fibroblast growth factor 23
FLJ21369 uncharacterized protein FLJ21369
GPC3 glypican 3
GRTP1 growth hormone regulated TBC protein 1
HHAT hedgehog acyltransferase
HOXA6 homeobox A6
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT31 keratin 31, type I
LIME1 Lck interacting transmembrane adaptor 1
LIMS2 LIM and senescent cell antigen-like domains 2
LPAR4 lysophosphatidic acid receptor 4
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
MATN3 matrilin 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MED31 mediator complex subunit 31
MGP matrix Gla protein
MRPS18C mitochondrial ribosomal protein S18C
MTSS1L metastasis suppressor 1-like
MYO1D myosin ID
NACA2 nascent polypeptide-associated complex alpha subunit 2
NGF nerve growth factor (beta polypeptide)
NPVF neuropeptide VF precursor
NTSR1 neurotensin receptor 1 (high affinity)
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBP2 oxysterol binding protein 2
PBOV1 prostate and breast cancer overexpressed 1
PCDHA5 protocadherin alpha 5
PGPEP1 pyroglutamyl-peptidase I
PID1 phosphotyrosine interaction domain containing 1
PODXL2 podocalyxin-like 2
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB40A RAB40A, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL3 ret finger protein-like 3
RGCC regulator of cell cycle
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMR3A submaxillary gland androgen regulated protein 3A
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTBN2 spectrin, beta, non-erythrocytic 2
STEAP4 STEAP family member 4
THSD4 thrombospondin, type I, domain containing 4
TIGD6 tigger transposable element derived 6
TNRC6B trinucleotide repeat containing 6B
TRAC T cell receptor alpha constant
TUBA4B tubulin, alpha 4b
ZNF222 zinc finger protein 222
ZNF749 zinc finger protein 749