yohimbic acid-2803 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the yohimbic acid-2803 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALOX15 arachidonate 15-lipoxygenase
ANKRD26 ankyrin repeat domain 26
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARL4C ADP-ribosylation factor-like 4C
ART1 ADP-ribosyltransferase 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP5 bone morphogenetic protein 5
C18ORF25 chromosome 18 open reading frame 25
CACTIN cactin, spliceosome C complex subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD82 CD82 molecule
CEP295 centrosomal protein 295kDa
CGA glycoprotein hormones, alpha polypeptide
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLEC11A C-type lectin domain family 11, member A
COL6A3 collagen, type VI, alpha 3
CRTC1 CREB regulated transcription coactivator 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DBT dihydrolipoamide branched chain transacylase E2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DICER1 dicer 1, ribonuclease type III
DMTN dematin actin binding protein
ETV5 ets variant 5
FANCA Fanconi anemia, complementation group A
FGF2 fibroblast growth factor 2 (basic)
FH fumarate hydratase
FPR1 formyl peptide receptor 1
GLS glutaminase
GRM7 glutamate receptor, metabotropic 7
GYG2 glycogenin 2
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IGFBP5 insulin-like growth factor binding protein 5
ING2 inhibitor of growth family, member 2
INO80D INO80 complex subunit D
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA1107 KIAA1107
KLHL26 kelch-like family member 26
KRT15 keratin 15, type I
LAMB3 laminin, beta 3
LMF2 lipase maturation factor 2
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP4 microtubule-associated protein 4
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MMP3 matrix metallopeptidase 3
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NAAA N-acylethanolamine acid amidase
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NREP neuronal regeneration related protein
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDE4C phosphodiesterase 4C, cAMP-specific
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHF8 PHD finger protein 8
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PLAGL1 pleiomorphic adenoma gene-like 1
PML promyelocytic leukemia
POMT2 protein-O-mannosyltransferase 2
PRDX2 peroxiredoxin 2
PSD3 pleckstrin and Sec7 domain containing 3
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RER1 retention in endoplasmic reticulum sorting receptor 1
RNMT RNA (guanine-7-) methyltransferase
RPL13P5 ribosomal protein L13 pseudogene 5
RUNX1 runt-related transcription factor 1
S100A6 S100 calcium binding protein A6
SCAPER S-phase cyclin A-associated protein in the ER
SCUBE3 signal peptide, CUB domain, EGF-like 3
SFRP4 secreted frizzled-related protein 4
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SLC25A30 solute carrier family 25, member 30
SNCG synuclein, gamma (breast cancer-specific protein 1)
ST5 suppression of tumorigenicity 5
STK24 serine/threonine kinase 24
STS steroid sulfatase (microsomal), isozyme S
STX2 syntaxin 2
TRIM3 tripartite motif containing 3
TTC9 tetratricopeptide repeat domain 9
UBQLN4 ubiquilin 4
UBR2 ubiquitin protein ligase E3 component n-recognin 2
WASL Wiskott-Aldrich syndrome-like
ZNF236 zinc finger protein 236
ZNF343 zinc finger protein 343
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADTRP androgen-dependent TFPI-regulating protein
AHNAK2 AHNAK nucleoprotein 2
AKAP5 A kinase (PRKA) anchor protein 5
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC7 armadillo repeat containing 7
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAK1 BCL2-antagonist/killer 1
BIRC7 baculoviral IAP repeat containing 7
BMP10 bone morphogenetic protein 10
BTBD2 BTB (POZ) domain containing 2
C19ORF73 chromosome 19 open reading frame 73
C1ORF159 chromosome 1 open reading frame 159
C1QB complement component 1, q subcomponent, B chain
CAMK1 calcium/calmodulin-dependent protein kinase I
CLCN6 chloride channel, voltage-sensitive 6
CRLF1 cytokine receptor-like factor 1
CTNNBIP1 catenin, beta interacting protein 1
ELMO3 engulfment and cell motility 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM204A family with sequence similarity 204, member A
FBXL15 F-box and leucine-rich repeat protein 15
FGF23 fibroblast growth factor 23
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXN2 forkhead box N2
GFI1 growth factor independent 1 transcription repressor
GLI3 GLI family zinc finger 3
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GSTA4 glutathione S-transferase alpha 4
GSTTP1 glutathione S-transferase theta pseudogene 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HMOX1 heme oxygenase 1
HYAL3 hyaluronoglucosaminidase 3
INHBE inhibin, beta E
INPP1 inositol polyphosphate-1-phosphatase
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT13 keratin 13, type I
LHX6 LIM homeobox 6
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC257152 uncharacterized LOC257152
LOC729164 hCG1732469
LYPD1 LY6/PLAUR domain containing 1
LZTR1 leucine-zipper-like transcription regulator 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN1 mucolipin 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MOSPD3 motile sperm domain containing 3
MRPL52 mitochondrial ribosomal protein L52
MX1 MX dynamin-like GTPase 1
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPTX1 neuronal pentraxin I
OLFML3 olfactomedin-like 3
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PARP12 poly (ADP-ribose) polymerase family, member 12
PC pyruvate carboxylase
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRPH peripherin
RASAL1 RAS protein activator like 1 (GAP1 like)
RLN1 relaxin 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLN sarcolipin
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPAG4 sperm associated antigen 4
SRPX sushi-repeat containing protein, X-linked
SSBP3 single stranded DNA binding protein 3
SULT4A1 sulfotransferase family 4A, member 1
SUN2 Sad1 and UNC84 domain containing 2
TGFBR3 transforming growth factor, beta receptor III
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRB thyroid hormone receptor, beta
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
TRIM36 tripartite motif containing 36
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
VEGFB vascular endothelial growth factor B
VWA1 von Willebrand factor A domain containing 1
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
ZFP37 ZFP37 zinc finger protein
ZNF205 zinc finger protein 205
ZNF493 zinc finger protein 493
ZNF639 zinc finger protein 639
ZNF701 zinc finger protein 701