xylometazoline-7020 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the xylometazoline-7020 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD5 abhydrolase domain containing 5
ADGRE5 adhesion G protein-coupled receptor E5
AKAP11 A kinase (PRKA) anchor protein 11
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARMCX4 armadillo repeat containing, X-linked 4
ARTN artemin
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
B9D1 B9 protein domain 1
BBS9 Bardet-Biedl syndrome 9
C10ORF95 chromosome 10 open reading frame 95
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CBX8 chromobox homolog 8
CCDC186 coiled-coil domain containing 186
CCPG1 cell cycle progression 1
CD70 CD70 molecule
CDC25C cell division cycle 25C
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCA1 chloride channel accessory 1
CNGB3 cyclic nucleotide gated channel beta 3
CYR61 cysteine-rich, angiogenic inducer, 61
DIO2 deiodinase, iodothyronine, type II
DPYSL4 dihydropyrimidinase-like 4
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DVL3 dishevelled segment polarity protein 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELOVL2 ELOVL fatty acid elongase 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ERCC4 excision repair cross-complementation group 4
FAM155A family with sequence similarity 155, member A
FAM212B family with sequence similarity 212, member B
FAM65A family with sequence similarity 65, member A
FH fumarate hydratase
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GALC galactosylceramidase
GK glycerol kinase
GLUD2 glutamate dehydrogenase 2
GP2 glycoprotein 2 (zymogen granule membrane)
HAUS6 HAUS augmin-like complex, subunit 6
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H2BC histone cluster 1, H2bc
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IRF6 interferon regulatory factor 6
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LIN7A lin-7 homolog A (C. elegans)
LOC100272216 uncharacterized LOC100272216
LTBP2 latent transforming growth factor beta binding protein 2
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGC12488
MXD4 MAX dimerization protein 4
MYBPC3 myosin binding protein C, cardiac
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDE1 nudE neurodevelopment protein 1
NF1 neurofibromin 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRSN2 neurensin 2
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PARVA parvin, alpha
PDGFB platelet-derived growth factor beta polypeptide
PHF20L1 PHD finger protein 20-like 1
PHF3 PHD finger protein 3
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PKNOX1 PBX/knotted 1 homeobox 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLXNA3 plexin A3
POM121 POM121 transmembrane nucleoporin
PRKCA protein kinase C, alpha
PROL1 proline rich, lacrimal 1
PTK6 protein tyrosine kinase 6
PTPRA protein tyrosine phosphatase, receptor type, A
PXN paxillin
RABGAP1 RAB GTPase activating protein 1
RARA retinoic acid receptor, alpha
RNF39 ring finger protein 39
SCARB2 scavenger receptor class B, member 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SIPA1 signal-induced proliferation-associated 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOCS6 suppressor of cytokine signaling 6
SOX4 SRY (sex determining region Y)-box 4
SPAST spastin
TEX15 testis expressed 15
TM2D1 TM2 domain containing 1
TMEM183A transmembrane protein 183A
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
UNC93B1 unc-93 homolog B1 (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VLDLR very low density lipoprotein receptor
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF557 zinc finger protein 557
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATAD3A ATPase family, AAA domain containing 3A
ATAD5 ATPase family, AAA domain containing 5
ATG2A autophagy related 2A
ATG2B autophagy related 2B
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
BCORL1 BCL6 corepressor-like 1
BTBD2 BTB (POZ) domain containing 2
C2CD2 C2 calcium-dependent domain containing 2
C5 complement component 5
CA11 carbonic anhydrase XI
CCNT1 cyclin T1
CEP85 centrosomal protein 85kDa
CEP97 centrosomal protein 97kDa
CHIC2 cysteine-rich hydrophobic domain 2
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CPTP ceramide-1-phosphate transfer protein
CUEDC1 CUE domain containing 1
CXORF56 chromosome X open reading frame 56
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DSCAM Down syndrome cell adhesion molecule
ECHDC3 enoyl CoA hydratase domain containing 3
ELP3 elongator acetyltransferase complex subunit 3
ERO1L ERO1-like (S. cerevisiae)
ETAA1 Ewing tumor-associated antigen 1
FA2H fatty acid 2-hydroxylase
FBXL15 F-box and leucine-rich repeat protein 15
FBXO22 F-box protein 22
FIP1L1 factor interacting with PAPOLA and CPSF1
GAS8 growth arrest-specific 8
GLCE glucuronic acid epimerase
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HPS6 Hermansky-Pudlak syndrome 6
IFITM1 interferon induced transmembrane protein 1
IFT140 intraflagellar transport 140
IL15RA interleukin 15 receptor, alpha
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLF3 Kruppel-like factor 3 (basic)
KRT13 keratin 13, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRP3 low density lipoprotein receptor-related protein 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAMLD1 mastermind-like domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MMP9 matrix metallopeptidase 9
MT1HL1 metallothionein 1H-like 1
MTCL1 microtubule crosslinking factor 1
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NBEAL2 neurobeachin-like 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NOL6 nucleolar protein 6 (RNA-associated)
NRGN neurogranin (protein kinase C substrate, RC3)
NUP62CL nucleoporin 62kDa C-terminal like
NUPL2 nucleoporin like 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PGP phosphoglycolate phosphatase
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAP1GAP2 RAP1 GTPase activating protein 2
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SHARPIN SHANK-associated RH domain interactor
SLC12A8 solute carrier family 12, member 8
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNIP1 Smad nuclear interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK25 serine/threonine kinase 25
STX5 syntaxin 5
SYBU syntabulin (syntaxin-interacting)
SYT17 synaptotagmin XVII
TRAPPC11 trafficking protein particle complex 11
TRAPPC13 trafficking protein particle complex 13
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
USP6 ubiquitin specific peptidase 6
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZFP30 ZFP30 zinc finger protein
ZMAT5 zinc finger, matrin-type 5
ZNF672 zinc finger protein 672
ZNHIT2 zinc finger, HIT-type containing 2