xylazine-4147 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the xylazine-4147 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADGRF5 adhesion G protein-coupled receptor F5
AKAP7 A kinase (PRKA) anchor protein 7
ALDOB aldolase B, fructose-bisphosphate
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARG1 arginase 1
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASMT acetylserotonin O-methyltransferase
ATP10B ATPase, class V, type 10B
C22ORF24 chromosome 22 open reading frame 24
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD209 CD209 molecule
CD5 CD5 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COL13A1 collagen, type XIII, alpha 1
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CST8 cystatin 8 (cystatin-related epididymal specific)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAPK1 death-associated protein kinase 1
DNAH7 dynein, axonemal, heavy chain 7
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
FAIM2 Fas apoptotic inhibitory molecule 2
FGFR2 fibroblast growth factor receptor 2
FLJ11292
FST follistatin
GEMIN7 gem (nuclear organelle) associated protein 7
GGT1 gamma-glutamyltransferase 1
GLB1L galactosidase, beta 1-like
HAL histidine ammonia-lyase
HFE hemochromatosis
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXB5 homeobox B5
HOXB6 homeobox B6
HOXC4 homeobox C4
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RN interleukin 1 receptor antagonist
IL2RB interleukin 2 receptor, beta
INSL4 insulin-like 4 (placenta)
JAM3 junctional adhesion molecule 3
KIF21B kinesin family member 21B
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRT2 keratin 2, type II
KRT38 keratin 38, type I
LAMB4 laminin, beta 4
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC100131510 uncharacterized LOC100131510
LOXL2 lysyl oxidase-like 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MCTP1 multiple C2 domains, transmembrane 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MINK1 misshapen-like kinase 1
MKL1 megakaryoblastic leukemia (translocation) 1
MMP11 matrix metallopeptidase 11
MUC8 mucin 8
MYOZ3 myozenin 3
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NNAT neuronatin
NOV nephroblastoma overexpressed
NPAS3 neuronal PAS domain protein 3
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRL neural retina leucine zipper
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR2C1 olfactory receptor, family 2, subfamily C, member 1
PAX8 paired box 8
PCDHGA10 protocadherin gamma subfamily A, 10
PDE2A phosphodiesterase 2A, cGMP-stimulated
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRDM14 PR domain containing 14
PRUNE2 prune homolog 2 (Drosophila)
PSG3 pregnancy specific beta-1-glycoprotein 3
PSG6 pregnancy specific beta-1-glycoprotein 6
RANBP3 RAN binding protein 3
RIMS1 regulating synaptic membrane exocytosis 1
RORA RAR-related orphan receptor A
SAMD4B sterile alpha motif domain containing 4B
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC39A9 solute carrier family 39, member 9
SOGA1 suppressor of glucose, autophagy associated 1
SOX2 SRY (sex determining region Y)-box 2
SPEG SPEG complex locus
SPON1 spondin 1, extracellular matrix protein
STS steroid sulfatase (microsomal), isozyme S
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAGLN3 transgelin 3
TBL1Y transducin (beta)-like 1, Y-linked
TLR1 toll-like receptor 1
TP53I11 tumor protein p53 inducible protein 11
TRBC1 T cell receptor beta constant 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding)
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZC2HC1C zinc finger, C2HC-type containing 1C

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AMPD3 adenosine monophosphate deaminase 3
ANKH ANKH inorganic pyrophosphate transport regulator
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASNSD1 asparagine synthetase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AUP1 ancient ubiquitous protein 1
C17ORF53 chromosome 17 open reading frame 53
C2ORF27A chromosome 2 open reading frame 27A
CALML5 calmodulin-like 5
CAPN15 calpain 15
CCNE1 cyclin E1
CD83 CD83 molecule
CD8A CD8a molecule
CDHR2 cadherin-related family member 2
CHKB choline kinase beta
CIC capicua transcriptional repressor
CLDN1 claudin 1
CORO7 coronin 7
CPB2 carboxypeptidase B2 (plasma)
DBF4B DBF4 zinc finger B
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FAM76A family with sequence similarity 76, member A
FBXO2 F-box protein 2
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FLJ22184
FOXD1 forkhead box D1
HDAC4 histone deacetylase 4
HIST1H1D histone cluster 1, H1d
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFI6 interferon, alpha-inducible protein 6
IGFBP3 insulin-like growth factor binding protein 3
IL22 interleukin 22
JUNB jun B proto-oncogene
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD7 potassium channel tetramerization domain containing 7
KDM8 lysine (K)-specific demethylase 8
LHX1 LIM homeobox 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED31 mediator complex subunit 31
MEFV Mediterranean fever
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOB3B MOB kinase activator 3B
MST1 macrophage stimulating 1
MUC3A mucin 3A, cell surface associated
NT5DC3 5'-nucleotidase domain containing 3
NUP62CL nucleoporin 62kDa C-terminal like
PACS1 phosphofurin acidic cluster sorting protein 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
POMT2 protein-O-mannosyltransferase 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRODH proline dehydrogenase (oxidase) 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFPL1S RFPL1 antisense RNA 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RND1 Rho family GTPase 1
RNF208 ring finger protein 208
RPL13P5 ribosomal protein L13 pseudogene 5
RPS14P3 ribosomal protein S14 pseudogene 3
SCAMP4 secretory carrier membrane protein 4
SH3BGR SH3 domain binding glutamate-rich protein
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SNX15 sorting nexin 15
SP1 Sp1 transcription factor
TCP10 t-complex 10
TET3 tet methylcytosine dioxygenase 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBR1 transforming growth factor, beta receptor 1
TLR2 toll-like receptor 2
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC5 transient receptor potential cation channel, subfamily C, member 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNC93B1 unc-93 homolog B1 (C. elegans)
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VN1R1 vomeronasal 1 receptor 1
ZBTB44 zinc finger and BTB domain containing 44
ZFHX4 zinc finger homeobox 4
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF551 zinc finger protein 551
ZNF862 zinc finger protein 862
ZW10 zw10 kinetochore protein