wortmannin-7002 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the wortmannin-7002 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDOB aldolase B, fructose-bisphosphate
APOE apolipoprotein E
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF95 chromosome 10 open reading frame 95
C14ORF93 chromosome 14 open reading frame 93
C19ORF73 chromosome 19 open reading frame 73
C2ORF27A chromosome 2 open reading frame 27A
CALHM2 calcium homeostasis modulator 2
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CD82 CD82 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFLAR CASP8 and FADD-like apoptosis regulator
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRYBG3 beta-gamma crystallin domain containing 3
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELOVL4 ELOVL fatty acid elongase 4
EPHA1 EPH receptor A1
EPOR erythropoietin receptor
ERN2 endoplasmic reticulum to nucleus signaling 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GM2A GM2 ganglioside activator
GPR153 G protein-coupled receptor 153
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HBP1 HMG-box transcription factor 1
HIST1H2BM histone cluster 1, H2bm
HIST1H2BO histone cluster 1, H2bo
HIST1H4D histone cluster 1, H4d
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDS iduronate 2-sulfatase
IFITM1 interferon induced transmembrane protein 1
ING4 inhibitor of growth family, member 4
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INSR insulin receptor
IRS2 insulin receptor substrate 2
KDM5A lysine (K)-specific demethylase 5A
KLHL24 kelch-like family member 24
LMF1 lipase maturation factor 1
LOC730101 uncharacterized LOC730101
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4 microtubule-associated protein 4
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPT microtubule-associated protein tau
MIIP migration and invasion inhibitory protein
MSMB microseminoprotein, beta-
MTA1 metastasis associated 1
NCAPH2 non-SMC condensin II complex, subunit H2
NF1 neurofibromin 1
NPFFR1 neuropeptide FF receptor 1
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
ORC5 origin recognition complex, subunit 5
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDAP1 PDGFA associated protein 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRE protein tyrosine phosphatase, receptor type, E
RECQL5 RecQ protein-like 5
RIN2 Ras and Rab interactor 2
RNF122 ring finger protein 122
SCAPER S-phase cyclin A-associated protein in the ER
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGSM2 small G protein signaling modulator 2
SIX2 SIX homeobox 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLIT2 slit homolog 2 (Drosophila)
SOX13 SRY (sex determining region Y)-box 13
STON1 stonin 1
TAPBP TAP binding protein (tapasin)
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRIB2 tribbles pseudokinase 2
TTC23 tetratricopeptide repeat domain 23
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YPEL5 yippee-like 5 (Drosophila)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCCHC24 zinc finger, CCHC domain containing 24
ZMAT5 zinc finger, matrin-type 5
ZNF10 zinc finger protein 10
ZNF287 zinc finger protein 287
ZNF589 zinc finger protein 589
ZNF606 zinc finger protein 606
ZNF816 zinc finger protein 816
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD3A ATPase family, AAA domain containing 3A
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
B3GAT3 beta-1,3-glucuronyltransferase 3
BAK1 BCL2-antagonist/killer 1
BMP4 bone morphogenetic protein 4
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF132 chromosome 14 open reading frame 132
C21ORF91 chromosome 21 open reading frame 91
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDR2L cerebellar degeneration-related protein 2-like
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP72 centrosomal protein 72kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST10 carbohydrate sulfotransferase 10
CIDEC cell death-inducing DFFA-like effector c
CLSPN claspin
CPTP ceramide-1-phosphate transfer protein
CXORF56 chromosome X open reading frame 56
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DOCK1 dedicator of cytokinesis 1
DOLK dolichol kinase
DUSP5 dual specificity phosphatase 5
FA2H fatty acid 2-hydroxylase
FBXO22 F-box protein 22
FHOD1 formin homology 2 domain containing 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPATCH3 G patch domain containing 3
GRWD1 glutamate-rich WD repeat containing 1
HCFC2 host cell factor C2
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
KLF2 Kruppel-like factor 2
KLHL21 kelch-like family member 21
KREMEN2 kringle containing transmembrane protein 2
LIG4 ligase IV, DNA, ATP-dependent
LIN7B lin-7 homolog B (C. elegans)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP5 low density lipoprotein receptor-related protein 5
LRRC20 leucine rich repeat containing 20
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
MAPK12 mitogen-activated protein kinase 12
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFSD12 major facilitator superfamily domain containing 12
MMP9 matrix metallopeptidase 9
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MTA2 metastasis associated 1 family, member 2
MVD mevalonate (diphospho) decarboxylase
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NHEJ1 nonhomologous end-joining factor 1
NRGN neurogranin (protein kinase C substrate, RC3)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
OTUD3 OTU deubiquitinase 3
PBLD phenazine biosynthesis-like protein domain containing
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD3 phospholipase D family, member 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
RAB23 RAB23, member RAS oncogene family
RAB32 RAB32, member RAS oncogene family
RNF2 ring finger protein 2
SETD8 SET domain containing (lysine methyltransferase) 8
SFT2D2 SFT2 domain containing 2
SH2B3 SH2B adaptor protein 3
SHPK sedoheptulokinase
SLC12A8 solute carrier family 12, member 8
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPAG7 sperm associated antigen 7
SPRYD7 SPRY domain containing 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TRAF2 TNF receptor-associated factor 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP36 ubiquitin specific peptidase 36
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VAV1 vav 1 guanine nucleotide exchange factor
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF254 zinc finger protein 254
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF778 zinc finger protein 778
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN26 zinc finger and SCAN domain containing 26