wnt signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state. (Gene Ontology, GO_0016055)
External Link http://amigo.geneontology.org/amigo/term/GO:0016055
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Genes

233 genes participating in the wnt signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AES amino-terminal enhancer of split
AMER1 APC membrane recruitment protein 1
AMER2 APC membrane recruitment protein 2
AMER3 APC membrane recruitment protein 3
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
APCDD1 adenomatosis polyposis coli down-regulated 1
ARL6 ADP-ribosylation factor-like 6
AXIN1 axin 1
AXIN2 axin 2
BCL9 B-cell CLL/lymphoma 9
BCL9L B-cell CLL/lymphoma 9-like
BRD7 bromodomain containing 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC88C coiled-coil domain containing 88C
CCND1 cyclin D1
CCNE1 cyclin E1
CCNY cyclin Y
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CDC73 cell division cycle 73
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK14 cyclin-dependent kinase 14
CELA1 chymotrypsin-like elastase family, member 1
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHD8 chromodomain helicase DNA binding protein 8
CPE carboxypeptidase E
CPZ carboxypeptidase Z
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1D casein kinase 1, delta
CSNK1G1 casein kinase 1, gamma 1
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTHRC1 collagen triple helix repeat containing 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTNND1 catenin (cadherin-associated protein), delta 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
CUL3 cullin 3
CYLD cylindromatosis (turban tumor syndrome)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DACT1 dishevelled-binding antagonist of beta-catenin 1
DACT3 dishevelled-binding antagonist of beta-catenin 3
DDB1 damage-specific DNA binding protein 1, 127kDa
DDIT3 DNA-damage-inducible transcript 3
DISC1 disrupted in schizophrenia 1
DIXDC1 DIX domain containing 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DKK4 dickkopf WNT signaling pathway inhibitor 4
DRAXIN dorsal inhibitory axon guidance protein
DRD2 dopamine receptor D2
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
ETV2 ets variant 2
FBXW11 F-box and WD repeat domain containing 11
FBXW4 F-box and WD repeat domain containing 4
FERMT2 fermitin family member 2
FGF8 fibroblast growth factor 8 (androgen-induced)
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FRZB frizzled-related protein
FZD1 frizzled class receptor 1
FZD10 frizzled class receptor 10
FZD2 frizzled class receptor 2
FZD3 frizzled class receptor 3
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
FZD6 frizzled class receptor 6
FZD7 frizzled class receptor 7
FZD8 frizzled class receptor 8
FZD9 frizzled class receptor 9
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GRHL3 grainyhead-like 3 (Drosophila)
GRK5 G protein-coupled receptor kinase 5
GRK6 G protein-coupled receptor kinase 6
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HBP1 HMG-box transcription factor 1
HHEX hematopoietically expressed homeobox
HIC1 hypermethylated in cancer 1
HMGXB4 HMG box domain containing 4
HOXB9 homeobox B9
INVS inversin
KDM6A lysine (K)-specific demethylase 6A
KLHL12 kelch-like family member 12
KREMEN1 kringle containing transmembrane protein 1
KREMEN2 kringle containing transmembrane protein 2
LDB1 LIM domain binding 1
LEF1 lymphoid enhancer-binding factor 1
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LRP4 low density lipoprotein receptor-related protein 4
LRP5 low density lipoprotein receptor-related protein 5
LRP5L low density lipoprotein receptor-related protein 5-like
LRP6 low density lipoprotein receptor-related protein 6
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LZTS2 leucine zipper, putative tumor suppressor 2
MACF1 microtubule-actin crosslinking factor 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MCC mutated in colorectal cancers
MED12 mediator complex subunit 12
MESDC2 mesoderm development candidate 2
MITF microphthalmia-associated transcription factor
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NDP Norrie disease (pseudoglioma)
NDRG2 NDRG family member 2
NKD1 naked cuticle homolog 1 (Drosophila)
NKD2 naked cuticle homolog 2 (Drosophila)
NKX2-5 NK2 homeobox 5
NLK nemo-like kinase
NPHP3 nephronophthisis 3 (adolescent)
NXN nucleoredoxin
OTULIN OTU deubiquitinase with linear linkage specificity
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PIAS4 protein inhibitor of activated STAT, 4
PITX2 paired-like homeodomain 2
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PORCN porcupine homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PROP1 PROP paired-like homeobox 1
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTK7 protein tyrosine kinase 7 (inactive)
PTPRU protein tyrosine phosphatase, receptor type, U
PYGO1 pygopus family PHD finger 1
PYGO2 pygopus family PHD finger 2
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RARG retinoic acid receptor, gamma
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF146 ring finger protein 146
RNF43 ring finger protein 43
ROR2 receptor tyrosine kinase-like orphan receptor 2
RSPO1 R-spondin 1
RSPO2 R-spondin 2
RSPO3 R-spondin 3
RSPO4 R-spondin 4
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
RYK receptor-like tyrosine kinase
RYR2 ryanodine receptor 2 (cardiac)
SDC1 syndecan 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SFRP5 secreted frizzled-related protein 5
SHH sonic hedgehog
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMO smoothened, frizzled class receptor
SNAI2 snail family zinc finger 2
SOST sclerostin
SOSTDC1 sclerostin domain containing 1
SOX17 SRY (sex determining region Y)-box 17
SOX4 SRY (sex determining region Y)-box 4
SPIN1 spindlin 1
STK11 serine/threonine kinase 11
STRN striatin, calmodulin binding protein
T T, brachyury homolog (mouse)
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TLE3 transducin-like enhancer of split 3
TLE4 transducin-like enhancer of split 4
TMEM198 transmembrane protein 198
TMEM88 transmembrane protein 88
TNIK TRAF2 and NCK interacting kinase
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRABD2A TraB domain containing 2A
TRABD2B TraB domain containing 2B
UBE2B ubiquitin-conjugating enzyme E2B
USP34 ubiquitin specific peptidase 34
VANGL2 VANGL planar cell polarity protein 2
VAX2 ventral anterior homeobox 2
VRK1 vaccinia related kinase 1
VRK2 vaccinia related kinase 2
VRK3 vaccinia related kinase 3
WDR61 WD repeat domain 61
WIF1 WNT inhibitory factor 1
WISP1 WNT1 inducible signaling pathway protein 1
WLS wntless Wnt ligand secretion mediator
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT11 wingless-type MMTV integration site family, member 11
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT6 wingless-type MMTV integration site family, member 6
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B
WNT8A wingless-type MMTV integration site family, member 8A
WNT8B wingless-type MMTV integration site family, member 8B
WNT9A wingless-type MMTV integration site family, member 9A
WNT9B wingless-type MMTV integration site family, member 9B
WWOX WW domain containing oxidoreductase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBED3 zinc finger, BED-type containing 3
ZBTB33 zinc finger and BTB domain containing 33
ZNRF3 zinc and ring finger 3
ZRANB1 zinc finger, RAN-binding domain containing 1