vitreous disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An eye and adnexa disease that is located in the vitreous of the eye. (Human Disease Ontology, DOID_9720)
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Genes

182 genes co-occuring with the disease vitreous disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FN1 fibronectin 1 1.80788
TGFB2 transforming growth factor, beta 2 1.57067
EMP2 epithelial membrane protein 2 1.24037
TGFB1 transforming growth factor, beta 1 1.22042
MTERF3 mitochondrial transcription termination factor 3 1.10552
TTC36 tetratricopeptide repeat domain 36 1.07614
GFAP glial fibrillary acidic protein 1.04882
FGF2 fibroblast growth factor 2 (basic) 1.04083
PDGFB platelet-derived growth factor beta polypeptide 1.01385
CTGF connective tissue growth factor 0.995283
RLBP1 retinaldehyde binding protein 1 0.991487
SEBOX SEBOX homeobox 0.923387
MLXIPL MLX interacting protein-like 0.892538
IGFBP6 insulin-like growth factor binding protein 6 0.880653
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.875738
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 0.870006
OPTC opticin 0.843802
RPE65 retinal pigment epithelium-specific protein 65kDa 0.822897
IL1B interleukin 1, beta 0.820437
IL6 interleukin 6 0.811821
TJP1 tight junction protein 1 0.803205
PLAT plasminogen activator, tissue 0.792951
SMAD2 SMAD family member 2 0.778613
MMP2 matrix metallopeptidase 2 0.773296
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.75005
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.714811
TIMP1 TIMP metallopeptidase inhibitor 1 0.713198
MMP9 matrix metallopeptidase 9 0.709572
SEPT8 septin 8 0.694702
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.694301
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.660404
CD68 CD68 molecule 0.658422
PLG plasminogen 0.65763
ITGA1 integrin, alpha 1 0.656441
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.647743
ADM adrenomedullin 0.644586
VEGFA vascular endothelial growth factor A 0.633956
TNC tenascin C 0.633956
SMAD3 SMAD family member 3 0.631205
TNF tumor necrosis factor 0.62885
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.606543
FGF1 fibroblast growth factor 1 (acidic) 0.60303
LHFPL5 lipoma HMGIC fusion partner-like 5 0.60186
MXD1 MAX dimerization protein 1 0.597571
CXCL8 chemokine (C-X-C motif) ligand 8 0.596792
MMP1 matrix metallopeptidase 1 0.58939
NCR3 natural cytotoxicity triggering receptor 3 0.581217
SMAD7 SMAD family member 7 0.577716
CCL2 chemokine (C-C motif) ligand 2 0.57305
MET MET proto-oncogene, receptor tyrosine kinase 0.569552
SCG2 secretogranin II 0.557509
GPR1 G protein-coupled receptor 1 0.556732
COL2A1 collagen, type II, alpha 1 0.551686
MMP3 matrix metallopeptidase 3 0.551298
LAMA1 laminin, alpha 1 0.550911
C1ORF167 chromosome 1 open reading frame 167 0.518805
GLB1 galactosidase, beta 1 0.516879
PDGFC platelet derived growth factor C 0.515725
GLUL glutamate-ammonia ligase 0.514571
TF transferrin 0.507273
TIMP2 TIMP metallopeptidase inhibitor 2 0.502292
SEPT11 septin 11 0.499997
ICAM1 intercellular adhesion molecule 1 0.498849
TFRC transferrin receptor 0.474119
CA6 carbonic anhydrase VI 0.472982
SV2A synaptic vesicle glycoprotein 2A 0.458619
CAPN5 calpain 5 0.455978
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.451454
MAP1B microtubule-associated protein 1B 0.445052
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.43753
THBS1 thrombospondin 1 0.431519
AGK acylglycerol kinase 0.430393
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.429642
NRN1 neuritin 1 0.420266
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.415024
MYLK3 myosin light chain kinase 3 0.410535
FOS FBJ murine osteosarcoma viral oncogene homolog 0.404184
NFIB nuclear factor I/B 0.403438
TSPO translocator protein (18kDa) 0.403438
OTX1 orthodenticle homeobox 1 0.400826
PCNA proliferating cell nuclear antigen 0.396725
CD22 CD22 molecule 0.394863
TRAF1 TNF receptor-associated factor 1 0.392257
BIN3 bridging integrator 3 0.389653
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.388538
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.388166
CLEC11A C-type lectin domain family 11, member A 0.379997
AGER advanced glycosylation end product-specific receptor 0.373698
HMGB1 high mobility group box 1 0.368149
TAC1 tachykinin, precursor 1 0.36704
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.365562
C4B complement component 4B (Chido blood group) 0.364824
PHYH phytanoyl-CoA 2-hydroxylase 0.363347
COL1A1 collagen, type I, alpha 1 0.354499
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.35082
VIM vimentin 0.342739
DEFA5 defensin, alpha 5, Paneth cell-specific 0.332487
MT1A metallothionein 1A 0.331391
KRT18 keratin 18, type I 0.329565
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.325187
SAG S-antigen; retina and pineal gland (arrestin) 0.324458
JUN jun proto-oncogene 0.323365
INHBA inhibin, beta A 0.323002
FGF5 fibroblast growth factor 5 0.321545
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 0.315003
LEF1 lymphoid enhancer-binding factor 1 0.314278
NPAT nuclear protein, ataxia-telangiectasia locus 0.308118
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.287952
MT2A metallothionein 2A 0.286519
KRT8 keratin 8, type II 0.285086
OCLN occludin 0.282582
ILK integrin-linked kinase 0.270819
DES desmin 0.269043
TP53 tumor protein p53 0.268687
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.256652
RNASEH2A ribonuclease H2, subunit A 0.25207
BIRC2 baculoviral IAP repeat containing 2 0.250663
COL1A2 collagen, type I, alpha 2 0.246799
PVR poliovirus receptor 0.243645
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.237009
VCL vinculin 0.23666
MMP8 matrix metallopeptidase 8 0.236312
CXCL6 chemokine (C-X-C motif) ligand 6 0.235964
HDGF hepatoma-derived growth factor 0.231795
IGF1 insulin-like growth factor 1 (somatomedin C) 0.229716
CCL22 chemokine (C-C motif) ligand 22 0.227297
ZEB1 zinc finger E-box binding homeobox 1 0.222822
LGALS3 lectin, galactoside-binding, soluble, 3 0.220081
TMSB10 thymosin beta 10 0.215653
KRT3 keratin 3, type II 0.211597
LIMK1 LIM domain kinase 1 0.210253
FASLG Fas ligand (TNF superfamily, member 6) 0.207912
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.206248
ALDOA aldolase A, fructose-bisphosphate 0.204593
CCL1 chemokine (C-C motif) ligand 1 0.203933
S100A4 S100 calcium binding protein A4 0.199033
VWF von Willebrand factor 0.199033
CCL11 chemokine (C-C motif) ligand 11 0.191408
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.188022
KRT4 keratin 4, type II 0.18651
CARD17 caspase recruitment domain family, member 17 0.18651
DCN decorin 0.18472
CCL4 chemokine (C-C motif) ligand 4 0.181798
OPN4 opsin 4 0.18151
IL1A interleukin 1, alpha 0.175947
LOXL2 lysyl oxidase-like 2 0.174354
EDN1 endothelin 1 0.173832
CCL3 chemokine (C-C motif) ligand 3 0.172799
HBEGF heparin-binding EGF-like growth factor 0.171535
CD34 CD34 molecule 0.170789
BMP2K BMP2 inducible kinase 0.167915
COL11A1 collagen, type XI, alpha 1 0.166095
RBP1 retinol binding protein 1, cellular 0.163729
ROM1 retinal outer segment membrane protein 1 0.160021
NPY neuropeptide Y 0.160021
THBS2 thrombospondin 2 0.159838
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.159302
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.146504
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.142203
LAMA3 laminin, alpha 3 0.141886
AXL AXL receptor tyrosine kinase 0.141038
PRSS3 protease, serine, 3 0.140887
BBS2 Bardet-Biedl syndrome 2 0.14061
THBD thrombomodulin 0.140597
CD163 CD163 molecule 0.138269
DPT dermatopontin 0.136568
GPX5 glutathione peroxidase 5 0.13601
GPX4 glutathione peroxidase 4 0.135888
GPX1 glutathione peroxidase 1 0.135321
COL18A1 collagen, type XVIII, alpha 1 0.135247
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.133298
CAT catalase 0.132162
LCK LCK proto-oncogene, Src family tyrosine kinase 0.131022
PTCH1 patched 1 0.130905
NF2 neurofibromin 2 (merlin) 0.129403
LTF lactotransferrin 0.127684
PLAUR plasminogen activator, urokinase receptor 0.127342
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.127279
LGALS1 lectin, galactoside-binding, soluble, 1 0.127023
CFI complement factor I 0.126829
SEPT5 septin 5 0.126664
LST1 leukocyte specific transcript 1 0.126497