vitexin-4588 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the vitexin-4588 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADAM2 ADAM metallopeptidase domain 2
ADCY9 adenylate cyclase 9
ADGRA2 adhesion G protein-coupled receptor A2
ADGRG1 adhesion G protein-coupled receptor G1
ADRB1 adrenoceptor beta 1
AHNAK AHNAK nucleoprotein
APOC1 apolipoprotein C-I
ARMC6 armadillo repeat containing 6
ATN1 atrophin 1
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BEGAIN brain-enriched guanylate kinase-associated
BMP10 bone morphogenetic protein 10
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C22ORF31 chromosome 22 open reading frame 31
C8ORF44 chromosome 8 open reading frame 44
CAMKMT calmodulin-lysine N-methyltransferase
CCDC40 coiled-coil domain containing 40
CD1C CD1c molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFP complement factor properdin
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
CREM cAMP responsive element modulator
CTRC chymotrypsin C (caldecrin)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DMPK dystrophia myotonica-protein kinase
DOCK6 dedicator of cytokinesis 6
DPF1 D4, zinc and double PHD fingers family 1
DUX1 double homeobox 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB1 EPH receptor B1
FAM188A family with sequence similarity 188, member A
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FRMD8 FERM domain containing 8
FRS2 fibroblast growth factor receptor substrate 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPNMB glycoprotein (transmembrane) nmb
GPR17 G protein-coupled receptor 17
HEMK1 HemK methyltransferase family member 1
HESX1 HESX homeobox 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL5RA interleukin 5 receptor, alpha
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LOC729164 hCG1732469
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MET MET proto-oncogene, receptor tyrosine kinase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MMP11 matrix metallopeptidase 11
MR1 major histocompatibility complex, class I-related
MSC musculin
MUC3A mucin 3A, cell surface associated
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
OMD osteomodulin
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBX2 pre-B-cell leukemia homeobox 2
PHC3 polyhomeotic homolog 3 (Drosophila)
PHF2 PHD finger protein 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITX1 paired-like homeodomain 1
PLCG1 phospholipase C, gamma 1
POU1F1 POU class 1 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RFXAP regulatory factor X-associated protein
RHCE Rh blood group, CcEe antigens
RNF6 ring finger protein (C3H2C3 type) 6
SC5D sterol-C5-desaturase
SCN11A sodium channel, voltage gated, type XI alpha subunit
SLC17A2 solute carrier family 17, member 2
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SOX15 SRY (sex determining region Y)-box 15
SPRR2B small proline-rich protein 2B
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
TCP10 t-complex 10
TMPRSS15 transmembrane protease, serine 15
TP63 tumor protein p63
TRIM2 tripartite motif containing 2
TSNAXIP1 translin-associated factor X interacting protein 1
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
UTRN utrophin
VCAN versican
WSB1 WD repeat and SOCS box containing 1
ZNF268 zinc finger protein 268
ZNF286A zinc finger protein 286A
ZNF549 zinc finger protein 549
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ATAD5 ATPase family, AAA domain containing 5
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BBS7 Bardet-Biedl syndrome 7
BNC1 basonuclin 1
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASZ1 castor zinc finger 1
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CEL carboxyl ester lipase
CEP112 centrosomal protein 112kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCA1 chloride channel accessory 1
CLDN11 claudin 11
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DTX2 deltex 2, E3 ubiquitin ligase
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
EDAR ectodysplasin A receptor
EDIL3 EGF-like repeats and discoidin I-like domains 3
EPHA4 EPH receptor A4
FA2H fatty acid 2-hydroxylase
FAM120C family with sequence similarity 120C
FAM53B family with sequence similarity 53, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXO2 F-box protein 2
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGGY FGGY carbohydrate kinase domain containing
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GPATCH2 G patch domain containing 2
GPATCH3 G patch domain containing 3
GPR1 G protein-coupled receptor 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRB7 growth factor receptor-bound protein 7
HDAC11 histone deacetylase 11
HOOK1 hook microtubule-tethering protein 1
IL17RB interleukin 17 receptor B
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KLHL36 kelch-like family member 36
KLK5 kallikrein-related peptidase 5
LAMC3 laminin, gamma 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMNB1 lamin B1
LOC100286895 cell division cycle 27 homolog pseudogene
LOC100287590 uncharacterized LOC100287590
LRP3 low density lipoprotein receptor-related protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEH1 melanoma antigen family H1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MDFI MyoD family inhibitor
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTERF4 mitochondrial transcription termination factor 4
MTMR6 myotubularin related protein 6
MYLIP myosin regulatory light chain interacting protein
NAG18 NAG18 mRNA
NME5 NME/NM23 family member 5
OLFML3 olfactomedin-like 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDZD2 PDZ domain containing 2
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC8 placenta-specific 8
PRICKLE3 prickle homolog 3 (Drosophila)
PRPH peripherin
RAB36 RAB36, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAYSD1 SAYSVFN motif domain containing 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNRPN small nuclear ribonucleoprotein polypeptide N
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STX17 syntaxin 17
SYNGR3 synaptogyrin 3
SYNPO synaptopodin
TAOK1 TAO kinase 1
TBXAS1 thromboxane A synthase 1 (platelet)
TMEM159 transmembrane protein 159
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YOD1 YOD1 deubiquitinase
ZC3H12A zinc finger CCCH-type containing 12A
ZNF253 zinc finger protein 253
ZNF254 zinc finger protein 254
ZNF442 zinc finger protein 442
ZNF747 zinc finger protein 747
ZNF821 zinc finger protein 821