vitexin-4413 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the vitexin-4413 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ALPPL2 alkaline phosphatase, placental-like 2
ANK1 ankyrin 1, erythrocytic
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOL6 apolipoprotein L, 6
ASIC1 acid sensing (proton gated) ion channel 1
ATG10 autophagy related 10
C3ORF18 chromosome 3 open reading frame 18
C5AR1 complement component 5a receptor 1
C6ORF10 chromosome 6 open reading frame 10
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD8A CD8a molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CNTNAP2 contactin associated protein-like 2
COL14A1 collagen, type XIV, alpha 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DRP2 dystrophin related protein 2
DTNB dystrobrevin, beta
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPX eosinophil peroxidase
ERO1LB ERO1-like beta (S. cerevisiae)
FAM189A1 family with sequence similarity 189, member A1
FAM212B family with sequence similarity 212, member B
FBXO41 F-box protein 41
FGF2 fibroblast growth factor 2 (basic)
FLNC filamin C, gamma
GAB1 GRB2-associated binding protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAS2L1 growth arrest-specific 2 like 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR162 G protein-coupled receptor 162
GSTA3 glutathione S-transferase alpha 3
HDAC5 histone deacetylase 5
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-F major histocompatibility complex, class I, F
HPCAL4 hippocalcin like 4
HRASLS2 HRAS-like suppressor 2
HTN1 histatin 1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL1RAP interleukin 1 receptor accessory protein
ITM2C integral membrane protein 2C
KIAA0040 KIAA0040
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LAMA2 laminin, alpha 2
LARP4B La ribonucleoprotein domain family, member 4B
LIM2 lens intrinsic membrane protein 2, 19kDa
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPAR3 lysophosphatidic acid receptor 3
LRRC17 leucine rich repeat containing 17
MAGEA8 melanoma antigen family A8
MBD2 methyl-CpG binding domain protein 2
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOB3B MOB kinase activator 3B
MXRA5 matrix-remodelling associated 5
MYL10 myosin, light chain 10, regulatory
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
OSBPL7 oxysterol binding protein-like 7
PCDH11X protocadherin 11 X-linked
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHF7 PHD finger protein 7
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTCRA pre T-cell antigen receptor alpha
RARA retinoic acid receptor, alpha
RASA3 RAS p21 protein activator 3
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASL10A RAS-like, family 10, member A
REC8 REC8 meiotic recombination protein
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN3 Ras and Rab interactor 3
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SETBP1 SET binding protein 1
SEZ6L seizure related 6 homolog (mouse)-like
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLN sarcolipin
SMAD6 SMAD family member 6
SRSF7 serine/arginine-rich splicing factor 7
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TBR1 T-box, brain, 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TTC39A tetratricopeptide repeat domain 39A
USP2 ubiquitin specific peptidase 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB17 zinc finger and BTB domain containing 17
ZNF358 zinc finger protein 358
ZNF639 zinc finger protein 639
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ATP10D ATPase, class V, type 10D
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF63 chromosome 11 open reading frame 63
C14ORF79 chromosome 14 open reading frame 79
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CLCN5 chloride channel, voltage-sensitive 5
CLDN1 claudin 1
CNR2 cannabinoid receptor 2 (macrophage)
CNTN1 contactin 1
CRYGC crystallin, gamma C
CTSF cathepsin F
DENND4A DENN/MADD domain containing 4A
DGAT1 diacylglycerol O-acyltransferase 1
DGKQ diacylglycerol kinase, theta 110kDa
DPY19L1P1 DPY19L1 pseudogene 1
DTX2 deltex 2, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC2 excision repair cross-complementation group 2
ETV6 ets variant 6
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GOLGA8B golgin A8 family, member B
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HYAL3 hyaluronoglucosaminidase 3
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQCG IQ motif containing G
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT15 keratin 15, type I
KRT6B keratin 6B, type II
LNPEP leucyl/cystinyl aminopeptidase
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MMP2 matrix metallopeptidase 2
MRPL41 mitochondrial ribosomal protein L41
MTERF4 mitochondrial transcription termination factor 4
MTMR6 myotubularin related protein 6
MX2 MX dynamin-like GTPase 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NKAIN1 Na+/K+ transporting ATPase interacting 1
NLRX1 NLR family member X1
NPIPB3 nuclear pore complex interacting protein family, member B3
NPY1R neuropeptide Y receptor Y1
NRGN neurogranin (protein kinase C substrate, RC3)
OSMR oncostatin M receptor
PCDHGB5 protocadherin gamma subfamily B, 5
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PORCN porcupine homolog (Drosophila)
PVRL3 poliovirus receptor-related 3
QPCT glutaminyl-peptide cyclotransferase
RFXAP regulatory factor X-associated protein
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
RNF39 ring finger protein 39
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A8 solute carrier family 12, member 8
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SNTA1 syntrophin, alpha 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR2B small proline-rich protein 2B
STRA6 stimulated by retinoic acid 6
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
UPP1 uridine phosphorylase 1
USP19 ubiquitin specific peptidase 19
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP30 ZFP30 zinc finger protein
ZNF204P zinc finger protein 204, pseudogene
ZNF532 zinc finger protein 532
ZNF654 zinc finger protein 654
ZNF747 zinc finger protein 747
ZW10 zw10 kinetochore protein