vitamin c_mus musculus_gpl6246_gse32994 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32994
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Genes

316 genes differentially expressed following the vitamin c_mus musculus_gpl6246_gse32994 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARS alanyl-tRNA synthetase
ACHE acetylcholinesterase (Yt blood group)
ACOT2 acyl-CoA thioesterase 2
AK4 adenylate kinase 4
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANKRD37 ankyrin repeat domain 37
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTLA B and T lymphocyte associated
C16ORF92 chromosome 16 open reading frame 92
C17ORF100 chromosome 17 open reading frame 100
CA6 carbonic anhydrase VI
CARD6 caspase recruitment domain family, member 6
CARS cysteinyl-tRNA synthetase
CCDC116 coiled-coil domain containing 116
CCL20 chemokine (C-C motif) ligand 20
CCR2 chemokine (C-C motif) receptor 2
CCR9 chemokine (C-C motif) receptor 9
CD70 CD70 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10
CIART circadian associated repressor of transcription
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DPPA3 developmental pluripotency associated 3
ELOVL4 ELOVL fatty acid elongase 4
ERO1L ERO1-like (S. cerevisiae)
FAM110B family with sequence similarity 110, member B
FAM20A family with sequence similarity 20, member A
FAM220A family with sequence similarity 220, member A
FBXL16 F-box and leucine-rich repeat protein 16
FIBIN fin bud initiation factor homolog (zebrafish)
FZD3 frizzled class receptor 3
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HBEGF heparin-binding EGF-like growth factor
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HDX highly divergent homeobox
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
HOXD8 homeobox D8
IARS isoleucyl-tRNA synthetase
ICA1 islet cell autoantigen 1, 69kDa
IER3 immediate early response 3
IL4I1 interleukin 4 induced 1
INHBA inhibin, beta A
ITGA8 integrin, alpha 8
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIF5C kinesin family member 5C
KLHDC7A kelch domain containing 7A
KLK14 kallikrein-related peptidase 14
KPRP keratinocyte proline-rich protein
KRT19 keratin 19, type I
KRT6A keratin 6A, type II
KRTAP5-2 keratin associated protein 5-2
L3MBTL4 l(3)mbt-like 4 (Drosophila)
MACROD2 MACRO domain containing 2
MARS methionyl-tRNA synthetase
MCAM melanoma cell adhesion molecule
MGLL monoglyceride lipase
MLH3 mutL homolog 3
MTERF2 mitochondrial transcription termination factor 2
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTM1 myotubularin 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NARF nuclear prelamin A recognition factor
NARS asparaginyl-tRNA synthetase
NEUROD6 neuronal differentiation 6
NEXN nexilin (F actin binding protein)
NPR3 natriuretic peptide receptor 3
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NUPR1 nuclear protein, transcriptional regulator, 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR1M1 olfactory receptor, family 1, subfamily M, member 1
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR2T4 olfactory receptor, family 2, subfamily T, member 4
OR51F2 olfactory receptor, family 51, subfamily F, member 2
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OR9I1 olfactory receptor, family 9, subfamily I, member 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PCDHB11 protocadherin beta 11
PCDHB17P protocadherin beta 17 pseudogene
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKL phosphofructokinase, liver
PLK2 polo-like kinase 2
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R26 protein phosphatase 1, regulatory subunit 26
RAB39B RAB39B, member RAS oncogene family
RALYL RALY RNA binding protein-like
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RGS16 regulator of G-protein signaling 16
RGS4 regulator of G-protein signaling 4
RHBDD2 rhomboid domain containing 2
RPS3A ribosomal protein S3A
S100A14 S100 calcium binding protein A14
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPRR2E small proline-rich protein 2E
TFRC transferrin receptor
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TSPAN12 tetraspanin 12
TSPAN7 tetraspanin 7
UNC13C unc-13 homolog C (C. elegans)
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WISP1 WNT1 inducible signaling pathway protein 1
ZNF169 zinc finger protein 169
ZNF761 zinc finger protein 761
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZSCAN22 zinc finger and SCAN domain containing 22

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
AHRR aryl-hydrocarbon receptor repressor
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMPD3 adenosine monophosphate deaminase 3
ANGPT1 angiopoietin 1
ANGPTL2 angiopoietin-like 2
ANLN anillin, actin binding protein
ANPEP alanyl (membrane) aminopeptidase
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
ARHGAP18 Rho GTPase activating protein 18
AS3MT arsenite methyltransferase
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP10A ATPase, class V, type 10A
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BIRC5 baculoviral IAP repeat containing 5
BNC1 basonuclin 1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BST2 bone marrow stromal cell antigen 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C11ORF87 chromosome 11 open reading frame 87
C1S complement component 1, s subcomponent
CALML3 calmodulin-like 3
CCNB1 cyclin B1
CCNB2 cyclin B2
CD34 CD34 molecule
CDA cytidine deaminase
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPP centromere protein P
CEP192 centrosomal protein 192kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CKAP2L cytoskeleton associated protein 2-like
CLEC2D C-type lectin domain family 2, member D
CLEC4C C-type lectin domain family 4, member C
CLSPN claspin
CRIP1 cysteine-rich protein 1 (intestinal)
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1
CSPP1 centrosome and spindle pole associated protein 1
CTAG2 cancer/testis antigen 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYCS cytochrome c, somatic
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DEPDC1 DEP domain containing 1
DIAPH3 diaphanous-related formin 3
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPT dermatopontin
ECT2 epithelial cell transforming 2
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
EPHA1 EPH receptor A1
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM64A family with sequence similarity 64, member A
FANCI Fanconi anemia, complementation group I
FEM1A fem-1 homolog a (C. elegans)
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOXL1 forkhead box L1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
G6PD glucose-6-phosphate dehydrogenase
GAS2L3 growth arrest-specific 2 like 3
GBP2 guanylate binding protein 2, interferon-inducible
GBP3 guanylate binding protein 3
GEN1 GEN1 Holliday junction 5' flap endonuclease
GLIPR1 GLI pathogenesis-related 1
GPR61 G protein-coupled receptor 61
HAUS5 HAUS augmin-like complex, subunit 5
HAUS6 HAUS augmin-like complex, subunit 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H1A histone cluster 1, H1a
HIST1H1T histone cluster 1, H1t
HIST1H2BH histone cluster 1, H2bh
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H4D histone cluster 1, H4d
HMGB1 high mobility group box 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IBSP integrin-binding sialoprotein
IDI1 isopentenyl-diphosphate delta isomerase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGFBP4 insulin-like growth factor binding protein 4
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
INSIG1 insulin induced gene 1
IRF7 interferon regulatory factor 7
ITGB7 integrin, beta 7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0101 KIAA0101
KIF11 kinesin family member 11
KIF15 kinesin family member 15
KIF20B kinesin family member 20B
KIF22 kinesin family member 22
KIF23 kinesin family member 23
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KNG1 kininogen 1
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
LCTL lactase-like
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LY6E lymphocyte antigen 6 complex, locus E
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MBNL3 muscleblind-like splicing regulator 3
MELK maternal embryonic leucine zipper kinase
NAPRT nicotinate phosphoribosyltransferase
NAV1 neuron navigator 1
NCAPD2 non-SMC condensin I complex, subunit D2
NCAPG non-SMC condensin I complex, subunit G
NEK2 NIMA-related kinase 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
NSG1 neuron specific gene family member 1
NUF2 NUF2, NDC80 kinetochore complex component
NUSAP1 nucleolar and spindle associated protein 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFML2B olfactomedin-like 2B
OLFML3 olfactomedin-like 3
OR6N2 olfactory receptor, family 6, subfamily N, member 2
PARP14 poly (ADP-ribose) polymerase family, member 14
PBK PDZ binding kinase
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCNP PEST proteolytic signal containing nuclear protein
PDE4D phosphodiesterase 4D, cAMP-specific
PENK proenkephalin
PGM2 phosphoglucomutase 2
PHF11 PHD finger protein 11
PHF20 PHD finger protein 20
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
PMCH pro-melanin-concentrating hormone
POC1B POC1 centriolar protein B
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRIM1 primase, DNA, polypeptide 1 (49kDa)
RAD51C RAD51 paralog C
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPP40 ribonuclease P/MRP 40kDa subunit
RRM1 ribonucleotide reductase M1
RTP4 receptor (chemosensory) transporter protein 4
S100A4 S100 calcium binding protein A4
S1PR3 sphingosine-1-phosphate receptor 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEPW1 selenoprotein W, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP4 secreted frizzled-related protein 4
SGK1 serum/glucocorticoid regulated kinase 1
SGOL2 shugoshin-like 2 (S. pombe)
SHCBP1 SHC SH2-domain binding protein 1
SKA3 spindle and kinetochore associated complex subunit 3
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLFN13 schlafen family member 13
SNED1 sushi, nidogen and EGF-like domains 1
SNORD47 small nucleolar RNA, C/D box 47
SNORD58B small nucleolar RNA, C/D box 58B
SPAG5 sperm associated antigen 5
SPON2 spondin 2, extracellular matrix protein
SPRR1A small proline-rich protein 1A
SRPX sushi-repeat containing protein, X-linked
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFBR3 transforming growth factor, beta receptor III
TK1 thymidine kinase 1, soluble
TMEM106A transmembrane protein 106A
TMEM26 transmembrane protein 26
TNN tenascin N
TOP2A topoisomerase (DNA) II alpha 170kDa
TPBG trophoblast glycoprotein
TPX2 TPX2, microtubule-associated
TRIP13 thyroid hormone receptor interactor 13
TSPAN11 tetraspanin 11
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UHRF1 ubiquitin-like with PHD and ring finger domains 1
XDH xanthine dehydrogenase
ZNF443 zinc finger protein 443
ZNF780B zinc finger protein 780B