vitamin c_mus musculus_gpl6246_gse19378 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE19378
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Genes

398 genes differentially expressed following the vitamin c_mus musculus_gpl6246_gse19378 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACER1 alkaline ceramidase 1
ACOT1 acyl-CoA thioesterase 1
ACP5 acid phosphatase 5, tartrate resistant
ADGRG1 adhesion G protein-coupled receptor G1
AIM1L absent in melanoma 1-like
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOX15 arachidonate 15-lipoxygenase
AMT aminomethyltransferase
ANKRD45 ankyrin repeat domain 45
ANO9 anoctamin 9
ANXA9 annexin A9
AP1M2 adaptor-related protein complex 1, mu 2 subunit
ARG1 arginase 1
ARHGAP32 Rho GTPase activating protein 32
ARHGAP8 Rho GTPase activating protein 8
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like
AS3MT arsenite methyltransferase
ASPRV1 aspartic peptidase, retroviral-like 1
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BAIAP2L1 BAI1-associated protein 2-like 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BEX1 brain expressed, X-linked 1
C14ORF39 chromosome 14 open reading frame 39
C15ORF48 chromosome 15 open reading frame 48
CA2 carbonic anhydrase II
CA5B carbonic anhydrase VB, mitochondrial
CALML3 calmodulin-like 3
CAPSL calcyphosine-like
CATSPERG catsper channel auxiliary subunit gamma
CCBL2 cysteine conjugate-beta lyase 2
CCDC115 coiled-coil domain containing 115
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CD38 CD38 molecule
CDCP1 CUB domain containing protein 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELF3 CUGBP, Elav-like family member 3
CERS3 ceramide synthase 3
CFAP70 cilia and flagella associated protein 70
CGN cingulin
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLDN4 claudin 4
CLDN6 claudin 6
CLDN7 claudin 7
CSTA cystatin A (stefin A)
CTHRC1 collagen triple helix repeat containing 1
CXCL16 chemokine (C-X-C motif) ligand 16
CYBB cytochrome b-245, beta polypeptide
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DMRTC1B DMRT-like family C1B
DNAH8 dynein, axonemal, heavy chain 8
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
DPP3 dipeptidyl-peptidase 3
DPPA2 developmental pluripotency associated 2
DPPA4 developmental pluripotency associated 4
DPPA5 developmental pluripotency associated 5
DUSP27 dual specificity phosphatase 27 (putative)
ELF5 E74-like factor 5 (ets domain transcription factor)
ELMOD1 ELMO/CED-12 domain containing 1
EPGN epithelial mitogen
EPHA1 EPH receptor A1
EPHX2 epoxide hydrolase 2, cytoplasmic
ESRRB estrogen-related receptor beta
FAM169A family with sequence similarity 169, member A
FOLR1 folate receptor 1 (adult)
GATA2 GATA binding protein 2
GIPC2 GIPC PDZ domain containing family, member 2
GJB5 gap junction protein, beta 5, 31.1kDa
GLRX glutaredoxin (thioltransferase)
GPA33 glycoprotein A33 (transmembrane)
GPNMB glycoprotein (transmembrane) nmb
GPR179 G protein-coupled receptor 179
GPR182 G protein-coupled receptor 182
GPX2 glutathione peroxidase 2
GRAMD1B GRAM domain containing 1B
GRHL2 grainyhead-like 2 (Drosophila)
GSDMA gasdermin A
GSTP1 glutathione S-transferase pi 1
HINT3 histidine triad nucleotide binding protein 3
HLA-A major histocompatibility complex, class I, A
HOOK1 hook microtubule-tethering protein 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HTRA4 HtrA serine peptidase 4
IFI16 interferon, gamma-inducible protein 16
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGB6 integrin, beta 6
KLK11 kallikrein-related peptidase 11
KLK13 kallikrein-related peptidase 13
KLK14 kallikrein-related peptidase 14
KLK6 kallikrein-related peptidase 6
KNG1 kininogen 1
KRT1 keratin 1, type II
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRTDAP keratinocyte differentiation-associated protein
LCE3C late cornified envelope 3C
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LRRC9 leucine rich repeat containing 9
M1AP meiosis 1 associated protein
MAGEA5 melanoma antigen family A5
MDK midkine (neurite growth-promoting factor 2)
MEP1B meprin A, beta
MORC1 MORC family CW-type zinc finger 1
MRGPRX1 MAS-related GPR, member X1
MUC1 mucin 1, cell surface associated
MYL7 myosin, light chain 7, regulatory
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
MZB1 marginal zone B and B1 cell-specific protein
NANOG Nanog homeobox
NIPAL2 NIPA-like domain containing 2
NLRC4 NLR family, CARD domain containing 4
NQO1 NAD(P)H dehydrogenase, quinone 1
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR3A1 olfactory receptor, family 3, subfamily A, member 1
OR5B21 olfactory receptor, family 5, subfamily B, member 21
OVOL1 ovo-like zinc finger 1
PAPL iron/zinc purple acid phosphatase-like protein
PECAM1 platelet/endothelial cell adhesion molecule 1
PHF11 PHD finger protein 11
PIWIL2 piwi-like RNA-mediated gene silencing 2
PLBD1 phospholipase B domain containing 1
PLK3 polo-like kinase 3
POF1B premature ovarian failure, 1B
PPIF peptidylprolyl isomerase F
PPL periplakin
PROM2 prominin 2
PRSS22 protease, serine, 22
PVRL4 poliovirus receptor-related 4
QPCT glutaminyl-peptide cyclotransferase
RAB15 RAB15, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RBM47 RNA binding motif protein 47
RDH16 retinol dehydrogenase 16 (all-trans)
RPL39L ribosomal protein L39-like
RPS4Y2 ribosomal protein S4, Y-linked 2
S100A14 S100 calcium binding protein A14
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SECTM1 secreted and transmembrane 1
SEPT1 septin 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC12A8 solute carrier family 12, member 8
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC38A4 solute carrier family 38, member 4
SLC44A4 solute carrier family 44, member 4
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLFN12 schlafen family member 12
SOX2 SRY (sex determining region Y)-box 2
SPRR1A small proline-rich protein 1A
SPTA1 spectrin, alpha, erythrocytic 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SYNGAP1 synaptic Ras GTPase activating protein 1
TACSTD2 tumor-associated calcium signal transducer 2
TBX20 T-box 20
TDRD12 tudor domain containing 12
TFCP2L1 transcription factor CP2-like 1
TGM1 transglutaminase 1
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TLR2 toll-like receptor 2
TMC3 transmembrane channel-like 3
TMEM45B transmembrane protein 45B
TMPRSS12 transmembrane (C-terminal) protease, serine 12
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TPD52 tumor protein D52
TRDN triadin
TRIM29 tripartite motif containing 29
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
TTC39A tetratricopeptide repeat domain 39A
UTF1 undifferentiated embryonic cell transcription factor 1
VWA3B von Willebrand factor A domain containing 3B
ZDHHC23 zinc finger, DHHC-type containing 23
ZNF616 zinc finger protein 616
ZNF705A zinc finger protein 705A

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACAT1 acetyl-CoA acetyltransferase 1
ACER3 alkaline ceramidase 3
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
AHNAK2 AHNAK nucleoprotein 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANTXR1 anthrax toxin receptor 1
APCDD1 adenomatosis polyposis coli down-regulated 1
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARSB arylsulfatase B
ASPN asporin
AXL AXL receptor tyrosine kinase
BCL2 B-cell CLL/lymphoma 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BOC BOC cell adhesion associated, oncogene regulated
C14ORF159 chromosome 14 open reading frame 159
C1ORF95 chromosome 1 open reading frame 95
C2ORF69 chromosome 2 open reading frame 69
C8ORF4 chromosome 8 open reading frame 4
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALCRL calcitonin receptor-like
CALD1 caldesmon 1
CCDC80 coiled-coil domain containing 80
CCND2 cyclin D2
CD53 CD53 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH13 cadherin 13
CDK6 cyclin-dependent kinase 6
CEMIP cell migration inducing protein, hyaluronan binding
CNN1 calponin 1, basic, smooth muscle
CNN2 calponin 2
CNN3 calponin 3, acidic
COL5A2 collagen, type V, alpha 2
COX20 COX20 cytochrome c oxidase assembly factor
CPNE2 copine II
CTSA cathepsin A
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DDR2 discoidin domain receptor tyrosine kinase 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
DZIP1L DAZ interacting zinc finger protein 1-like
ECE1 endothelin converting enzyme 1
EFHD1 EF-hand domain family, member D1
EFNA3 ephrin-A3
EGR2 early growth response 2
EHD3 EH-domain containing 3
EIF5A2 eukaryotic translation initiation factor 5A2
ELF4 E74-like factor 4 (ets domain transcription factor)
EMP3 epithelial membrane protein 3
EMX2 empty spiracles homeobox 2
ENO3 enolase 3 (beta, muscle)
EPPIN epididymal peptidase inhibitor
ESR1 estrogen receptor 1
ETV6 ets variant 6
EVC Ellis van Creveld protein
FBLN1 fibulin 1
FBLN2 fibulin 2
FBLN5 fibulin 5
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGGY FGGY carbohydrate kinase domain containing
FIBIN fin bud initiation factor homolog (zebrafish)
FOXC1 forkhead box C1
FOXD1 forkhead box D1
FRZB frizzled-related protein
FSTL1 follistatin-like 1
FUT2 fucosyltransferase 2 (secretor status included)
FZD3 frizzled class receptor 3
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18
GBP6 guanylate binding protein family, member 6
GFRA2 GDNF family receptor alpha 2
GML glycosylphosphatidylinositol anchored molecule like
GOLIM4 golgi integral membrane protein 4
GPHA2 glycoprotein hormone alpha 2
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HEG1 heart development protein with EGF-like domains 1
HES6 hes family bHLH transcription factor 6
HMGA1 high mobility group AT-hook 1
HOXC5 homeobox C5
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA11 integrin, alpha 11
KATNAL1 katanin p60 subunit A-like 1
KDM7A lysine (K)-specific demethylase 7A
KLHDC1 kelch domain containing 1
KRTAP10-10 keratin associated protein 10-10
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LIPA lipase A, lysosomal acid, cholesterol esterase
LIX1L Lix1 homolog (chicken) like
LOC100506944 uncharacterized LOC100506944
LOR loricrin
LOX lysyl oxidase
LOXL2 lysyl oxidase-like 2
LPAR4 lysophosphatidic acid receptor 4
LTBP1 latent transforming growth factor beta binding protein 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAOA monoamine oxidase A
MAP2K6 mitogen-activated protein kinase kinase 6
MCC mutated in colorectal cancers
MED4 mediator complex subunit 4
MEIS2 Meis homeobox 2
METTL23 methyltransferase like 23
MKX mohawk homeobox
MMP9 matrix metallopeptidase 9
MPDZ multiple PDZ domain protein
MRGPRX3 MAS-related GPR, member X3
MSANTD1 Myb/SANT-like DNA-binding domain containing 1
MT4 metallothionein 4
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYOM1 myomesin 1
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NCAM1 neural cell adhesion molecule 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRP1 neuropilin 1
NTHL1 nth endonuclease III-like 1 (E. coli)
NUAK1 NUAK family, SNF1-like kinase, 1
NUDCD3 NudC domain containing 3
NYNRIN NYN domain and retroviral integrase containing
OGN osteoglycin
P3H1 prolyl 3-hydroxylase 1
P3H2 prolyl 3-hydroxylase 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PALMD palmdelphin
PARD6G par-6 family cell polarity regulator gamma
PCDH18 protocadherin 18
PCDH19 protocadherin 19
PCDHB11 protocadherin beta 11
PDE8B phosphodiesterase 8B
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POSTN periostin, osteoblast specific factor
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PRELP proline/arginine-rich end leucine-rich repeat protein
PRICKLE2 prickle homolog 2 (Drosophila)
PROM1 prominin 1
PRSS23 protease, serine, 23
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PXMP4 peroxisomal membrane protein 4, 24kDa
RASA4 RAS p21 protein activator 4
RGS4 regulator of G-protein signaling 4
RND3 Rho family GTPase 3
RNF13 ring finger protein 13
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPL18A ribosomal protein L18a
SAMD14 sterile alpha motif domain containing 14
SCARA5 scavenger receptor class A, member 5
SCUBE3 signal peptide, CUB domain, EGF-like 3
SELENBP1 selenium binding protein 1
SEPN1 selenoprotein N, 1
SEPT10 septin 10
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFRP4 secreted frizzled-related protein 4
SLC22A15 solute carrier family 22, member 15
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC41A2 solute carrier family 41 (magnesium transporter), member 2
SLC7A14 solute carrier family 7, member 14
SLIT3 slit homolog 3 (Drosophila)
SNAI2 snail family zinc finger 2
SOS2 son of sevenless homolog 2 (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
SPRR2B small proline-rich protein 2B
SPTSSB serine palmitoyltransferase, small subunit B
SSBP2 single-stranded DNA binding protein 2
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STXBP3 syntaxin binding protein 3
SULF1 sulfatase 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYPL2 synaptophysin-like 2
TAC1 tachykinin, precursor 1
TAGLN transgelin
TBC1D12 TBC1 domain family, member 12
TGFB2 transforming growth factor, beta 2
THAP2 THAP domain containing, apoptosis associated protein 2
THBS1 thrombospondin 1
THEM5 thioesterase superfamily member 5
TIMP3 TIMP metallopeptidase inhibitor 3
TLL1 tolloid-like 1
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TMEM35 transmembrane protein 35
TPM1 tropomyosin 1 (alpha)
TRH thyrotropin-releasing hormone
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TUBB3 tubulin, beta 3 class III
USP18 ubiquitin specific peptidase 18
VIM vimentin
VLDLR very low density lipoprotein receptor
WLS wntless Wnt ligand secretion mediator
ZC3H12C zinc finger CCCH-type containing 12C
ZC3H6 zinc finger CCCH-type containing 6
ZCCHC17 zinc finger, CCHC domain containing 17
ZEB1 zinc finger E-box binding homeobox 1
ZNF189 zinc finger protein 189
ZNF551 zinc finger protein 551