vitamin c_mus musculus_gpl6246_gse19377 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE19377
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Genes

244 genes differentially expressed following the vitamin c_mus musculus_gpl6246_gse19377 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AHSG alpha-2-HS-glycoprotein
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AS3MT arsenite methyltransferase
AVIL advillin
BEX4 brain expressed, X-linked 4
BHMT2 betaine--homocysteine S-methyltransferase 2
C1ORF110 chromosome 1 open reading frame 110
C1R complement component 1, r subcomponent
CA3 carbonic anhydrase III
CCL8 chemokine (C-C motif) ligand 8
CFB complement factor B
CLEC3B C-type lectin domain family 3, member B
CLIC3 chloride intracellular channel 3
CLNS1A chloride channel, nucleotide-sensitive, 1A
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
COQ3 coenzyme Q3 methyltransferase
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DPP4 dipeptidyl-peptidase 4
ECT2L epithelial cell transforming 2 like
FBXO32 F-box protein 32
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FETUB fetuin B
FMO1 flavin containing monooxygenase 1
FRRS1 ferric-chelate reductase 1
GAS2L3 growth arrest-specific 2 like 3
GBP2 guanylate binding protein 2, interferon-inducible
GBP3 guanylate binding protein 3
GBP4 guanylate binding protein 4
GBP6 guanylate binding protein family, member 6
GDA guanine deaminase
GDF3 growth differentiation factor 3
GDPGP1 GDP-D-glucose phosphorylase 1
GLIPR1 GLI pathogenesis-related 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HDAC9 histone deacetylase 9
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI16 interferon, gamma-inducible protein 16
IFI44 interferon-induced protein 44
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL1RL2 interleukin 1 receptor-like 2
ILDR1 immunoglobulin-like domain containing receptor 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRF7 interferon regulatory factor 7
IRGM immunity-related GTPase family, M
ITGB4 integrin, beta 4
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
KNG1 kininogen 1
LBP lipopolysaccharide binding protein
LGI2 leucine-rich repeat LGI family, member 2
LIPF lipase, gastric
LUM lumican
LVRN laeverin
LY75 lymphocyte antigen 75
MANSC1 MANSC domain containing 1
MBOAT1 membrane bound O-acyltransferase domain containing 1
MC3R melanocortin 3 receptor
MFSD2A major facilitator superfamily domain containing 2A
MORC1 MORC family CW-type zinc finger 1
MX2 MX dynamin-like GTPase 2
MYL9 myosin, light chain 9, regulatory
MYO9A myosin IXA
MYOCD myocardin
MYOZ2 myozenin 2
NAT8L N-acetyltransferase 8-like (GCN5-related, putative)
NEFL neurofilament, light polypeptide
NIPAL2 NIPA-like domain containing 2
NPY2R neuropeptide Y receptor Y2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OMG oligodendrocyte myelin glycoprotein
OR2V1 olfactory receptor, family 2, subfamily V, member 1
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP14 poly (ADP-ribose) polymerase family, member 14
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PLP1 proteolipid protein 1
PM20D1 peptidase M20 domain containing 1
PMCH pro-melanin-concentrating hormone
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
RANBP17 RAN binding protein 17
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPL11 ribosomal protein L11
RTP4 receptor (chemosensory) transporter protein 4
SCN10A sodium channel, voltage gated, type X alpha subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3RF2 SH3 domain containing ring finger 2
SLC10A4 solute carrier family 10, member 4
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SLC22A25 solute carrier family 22, member 25
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNHG1 small nucleolar RNA host gene 1
SOSTDC1 sclerostin domain containing 1
SP100 SP100 nuclear antigen
SPACA1 sperm acrosome associated 1
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STRIP2 striatin interacting protein 2
SYK spleen tyrosine kinase
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TFCP2L1 transcription factor CP2-like 1
TLR2 toll-like receptor 2
TMEM184A transmembrane protein 184A
TRPC5OS TRPC5 opposite strand
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSPAN8 tetraspanin 8
TUBA3E tubulin, alpha 3e
TYRP1 tyrosinase-related protein 1
UNC93A unc-93 homolog A (C. elegans)
USP18 ubiquitin specific peptidase 18
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR25 WD repeat domain 25
XAF1 XIAP associated factor 1
ZBP1 Z-DNA binding protein 1

decreased expression

Symbol Name
ABRACL ABRA C-terminal like
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADGRB3 adhesion G protein-coupled receptor B3
ADGRE1 adhesion G protein-coupled receptor E1
ADGRL2 adhesion G protein-coupled receptor L2
ALCAM activated leukocyte cell adhesion molecule
ANKRD37 ankyrin repeat domain 37
ANXA10 annexin A10
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP20 Rho GTPase activating protein 20
ASPN asporin
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA6 carbonic anhydrase VI
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCER1 coiled-coil glutamate-rich protein 1
CDO1 cysteine dioxygenase type 1
CHD7 chromodomain helicase DNA binding protein 7
CHODL chondrolectin
CSMD3 CUB and Sushi multiple domains 3
CST9 cystatin 9 (testatin)
CTTNBP2 cortactin binding protein 2
DGKB diacylglycerol kinase, beta 90kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFHD1 EF-hand domain family, member D1
EGFLAM EGF-like, fibronectin type III and laminin G domains
FABP7 fatty acid binding protein 7, brain
FAM71F2 family with sequence similarity 71, member F2
FAT3 FAT atypical cadherin 3
FIBIN fin bud initiation factor homolog (zebrafish)
FOXD2 forkhead box D2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GOLIM4 golgi integral membrane protein 4
GPR21 G protein-coupled receptor 21
GPR50 G protein-coupled receptor 50
HAPLN1 hyaluronan and proteoglycan link protein 1
HNF4G hepatocyte nuclear factor 4, gamma
HOMER2 homer scaffolding protein 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL4I1 interleukin 4 induced 1
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRRC3 leucine rich repeat containing 3
LST1 leukocyte specific transcript 1
LTBP4 latent transforming growth factor beta binding protein 4
LYZ lysozyme
MAMLD1 mastermind-like domain containing 1
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
MARS methionyl-tRNA synthetase
MCTP1 multiple C2 domains, transmembrane 1
MIR218-1 microRNA 218-1
MMP3 matrix metallopeptidase 3
MRC1 mannose receptor, C type 1
MRGPRX3 MAS-related GPR, member X3
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MZF1 myeloid zinc finger 1
NARF nuclear prelamin A recognition factor
NCAM1 neural cell adhesion molecule 1
NCAM2 neural cell adhesion molecule 2
NDNF neuron-derived neurotrophic factor
NPPC natriuretic peptide C
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRCAM neuronal cell adhesion molecule
NRP2 neuropilin 2
NYX nyctalopin
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OR6N2 olfactory receptor, family 6, subfamily N, member 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCDH10 protocadherin 10
PCDH11X protocadherin 11 X-linked
PCDH17 protocadherin 17
PCDH9 protocadherin 9
PDE7B phosphodiesterase 7B
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKL phosphofructokinase, liver
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1
PODN podocan
PRSS3 protease, serine, 3
PTCHD1 patched domain containing 1
PTPRD protein tyrosine phosphatase, receptor type, D
RGMB repulsive guidance molecule family member b
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SFN stratifin
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPP1 secreted phosphoprotein 1
STC1 stanniocalcin 1
STC2 stanniocalcin 2
SYT1 synaptotagmin I
TACR3 tachykinin receptor 3
TCEAL6 transcription elongation factor A (SII)-like 6
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM215 transmembrane protein 215
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIB3 tribbles pseudokinase 3
TSLP thymic stromal lymphopoietin
TUFT1 tuftelin 1
UNC13C unc-13 homolog C (C. elegans)
USP17L5 ubiquitin specific peptidase 17-like family member 5
VLDLR very low density lipoprotein receptor
ZNF280B zinc finger protein 280B