viral hepatitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hepatitis that involves viral infection causing inflammation of the liver. (Human Disease Ontology, DOID_1884)
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Genes

229 genes co-occuring with the disease viral hepatitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HBE1 hemoglobin, epsilon 1 1.82549
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.82504
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.7903
F2 coagulation factor II (thrombin) 1.70451
AFP alpha-fetoprotein 1.68861
IFNA1 interferon, alpha 1 1.65385
FGL2 fibrinogen-like 2 1.59966
ABHD14A abhydrolase domain containing 14A 1.56933
ALPPL2 alkaline phosphatase, placental-like 2 1.56755
ALPP alkaline phosphatase, placental 1.56667
ALPL alkaline phosphatase, liver/bone/kidney 1.56622
GGT1 gamma-glutamyltransferase 1 1.50886
ALB albumin 1.46847
CD4 CD4 molecule 1.25428
ASGR2 asialoglycoprotein receptor 2 1.17808
ASGR1 asialoglycoprotein receptor 1 1.15965
IFNA2 interferon, alpha 2 1.11015
KCTD9 potassium channel tetramerization domain containing 9 1.09923
TNF tumor necrosis factor 1.05387
FTH1 ferritin, heavy polypeptide 1 1.03956
FTL ferritin, light polypeptide 1.03956
GGT2 gamma-glutamyltransferase 2 1.01469
CD79A CD79a molecule, immunoglobulin-associated alpha 0.988114
HP haptoglobin 0.97128
IFNL3 interferon, lambda 3 0.967502
TF transferrin 0.967502
HPR haptoglobin-related protein 0.964567
FASLG Fas ligand (TNF superfamily, member 6) 0.954943
HFE hemochromatosis 0.945354
PDGFB platelet-derived growth factor beta polypeptide 0.944521
ADAM32 ADAM metallopeptidase domain 32 0.929587
FBL fibrillarin 0.911845
G6PD glucose-6-phosphate dehydrogenase 0.882701
IFNL1 interferon, lambda 1 0.877786
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.868368
FBLL1 fibrillarin-like 1 0.86714
CLEC2B C-type lectin domain family 2, member B 0.838476
TGFB1 transforming growth factor, beta 1 0.837246
IFNL2 interferon, lambda 2 0.834378
DGKH diacylglycerol kinase, eta 0.820437
STAT1 signal transducer and activator of transcription 1, 91kDa 0.817155
CLEC3A C-type lectin domain family 3, member A 0.77207
PNPLA3 patatin-like phospholipase domain containing 3 0.76431
CLTC clathrin, heavy chain (Hc) 0.760639
GDA guanine deaminase 0.759824
AKR1C2 aldo-keto reductase family 1, member C2 0.753713
CLEC10A C-type lectin domain family 10, member A 0.741517
BCHE butyrylcholinesterase 0.737865
UGP2 UDP-glucose pyrophosphorylase 2 0.734622
CP ceruloplasmin (ferroxidase) 0.668345
LYZ lysozyme 0.643009
TLR3 toll-like receptor 3 0.639857
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.636315
KRAS Kirsten rat sarcoma viral oncogene homolog 0.619442
F5 coagulation factor V (proaccelerin, labile factor) 0.609666
HAMP hepcidin antimicrobial peptide 0.59874
IL2 interleukin 2 0.594454
TTR transthyretin 0.590169
CLEC4G C-type lectin domain family 4, member G 0.589779
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.56722
NT5E 5'-nucleotidase, ecto (CD73) 0.566443
CRP C-reactive protein, pentraxin-related 0.563335
PRF1 perforin 1 (pore forming protein) 0.557897
IL6 interleukin 6 0.554791
IFNB1 interferon, beta 1, fibroblast 0.551686
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.550522
TIMP1 TIMP metallopeptidase inhibitor 1 0.541217
FN1 fibronectin 1 0.540055
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.536183
MX1 MX dynamin-like GTPase 1 0.514571
INS insulin 0.512648
B2M beta-2-microglobulin 0.508424
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.503824
SOD2 superoxide dismutase 2, mitochondrial 0.500379
CLEC9A C-type lectin domain family 9, member A 0.499231
F8 coagulation factor VIII, procoagulant component 0.498849
CDSN corneodesmosin 0.495411
SAG S-antigen; retina and pineal gland (arrestin) 0.492359
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.470332
IGHV3-9 immunoglobulin heavy variable 3-9 0.467684
FOXP3 forkhead box P3 0.467684
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.466928
PLG plasminogen 0.463905
GOLGA5 golgin A5 0.461639
CARTPT CART prepropeptide 0.459373
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.458619
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.446558
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.437154
RHOC ras homolog family member C 0.435275
LAP3 leucine aminopeptidase 3 0.42814
HAL histidine ammonia-lyase 0.426265
F3 coagulation factor III (thromboplastin, tissue factor) 0.420641
B3GAT1 beta-1,3-glucuronyltransferase 1 0.419517
VWCE von Willebrand factor C and EGF domains 0.409414
ALPI alkaline phosphatase, intestinal 0.409414
F9 coagulation factor IX 0.408666
POMC proopiomelanocortin 0.407919
USP18 ubiquitin specific peptidase 18 0.407172
RPL30 ribosomal protein L30 0.404557
NDRG3 NDRG family member 3 0.399707
CD69 CD69 molecule 0.396725
SOS1 son of sevenless homolog 1 (Drosophila) 0.394863
IL1B interleukin 1, beta 0.394863
CAT catalase 0.390769
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.390769
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.390397
KRT18 keratin 18, type I 0.389281
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.387794
HLA-C major histocompatibility complex, class I, C 0.385936
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.383708
ACTA1 actin, alpha 1, skeletal muscle 0.383337
LRRC3B leucine rich repeat containing 3B 0.38111
PCNA proliferating cell nuclear antigen 0.379997
THPO thrombopoietin 0.379997
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.378514
IRF9 interferon regulatory factor 9 0.377773
TCF12 transcription factor 12 0.375179
ADA adenosine deaminase 0.374809
BICD1 bicaudal D homolog 1 (Drosophila) 0.371847
RAI14 retinoic acid induced 14 0.371477
IFNA17 interferon, alpha 17 0.369997
RCE1 Ras converting CAAX endopeptidase 1 0.368888
ICAM1 intercellular adhesion molecule 1 0.365562
GPC3 glypican 3 0.365193
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.364824
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.358551
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.357446
KRT7 keratin 7, type II 0.356709
NCALD neurocalcin delta 0.354499
TP53 tumor protein p53 0.347144
NT5C 5', 3'-nucleotidase, cytosolic 0.342372
LCAT lecithin-cholesterol acyltransferase 0.334681
TLR7 toll-like receptor 7 0.325187
PTH parathyroid hormone 0.324823
APOA1 apolipoprotein A-I 0.324823
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.323002
PRRC2A proline-rich coiled-coil 2A 0.321909
ARMC10 armadillo repeat containing 10 0.320454
SORD sorbitol dehydrogenase 0.319726
THEM5 thioesterase superfamily member 5 0.319363
LEP leptin 0.316092
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.313552
IL10RA interleukin 10 receptor, alpha 0.310652
THBD thrombomodulin 0.31029
IFNA5 interferon, alpha 5 0.306672
CD83 CD83 molecule 0.304864
GPX1 glutathione peroxidase 1 0.303059
WAPAL wings apart-like homolog (Drosophila) 0.300894
STAT4 signal transducer and activator of transcription 4 0.298011
H1FX H1 histone family, member X 0.297291
IL10 interleukin 10 0.294053
DEPDC5 DEP domain containing 5 0.293694
CD81 CD81 molecule 0.293334
GCG glucagon 0.292975
PEX3 peroxisomal biogenesis factor 3 0.292257
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.291539
GOLIM4 golgi integral membrane protein 4 0.279011
URGCP upregulator of cell proliferation 0.278297
GAL galanin/GMAP prepropeptide 0.277227
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.276514
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.274021
TRAP1 TNF receptor-associated protein 1 0.265494
TICAM1 toll-like receptor adaptor molecule 1 0.25207
HLA-A major histocompatibility complex, class I, A 0.249257
TRIM37 tripartite motif containing 37 0.247501
IFNA21 interferon, alpha 21 0.24715
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.239799
KRT19 keratin 19, type I 0.238752
MMP1 matrix metallopeptidase 1 0.232836
GSTA3 glutathione S-transferase alpha 3 0.232142
GSTA2 glutathione S-transferase alpha 2 0.231102
GSTA4 glutathione S-transferase alpha 4 0.230063
GSTA1 glutathione S-transferase alpha 1 0.22454
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.223165
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.222479
LTF lactotransferrin 0.220424
LPA lipoprotein, Lp(a) 0.219398
MET MET proto-oncogene, receptor tyrosine kinase 0.215992
CASR calcium-sensing receptor 0.215314
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 0.213283
SOCS3 suppressor of cytokine signaling 3 0.212271
GUSB glucuronidase, beta 0.212271
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.211934
TLR4 toll-like receptor 4 0.211934
AHSG alpha-2-HS-glycoprotein 0.209248
FCRL4 Fc receptor-like 4 0.209248
NINJ1 ninjurin 1 0.208579
GFER growth factor, augmenter of liver regeneration 0.208245
CXCL8 chemokine (C-X-C motif) ligand 8 0.20658
NCAM1 neural cell adhesion molecule 1 0.206248
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.202946
CD96 CD96 molecule 0.200982
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.200656
CD40 CD40 molecule, TNF receptor superfamily member 5 0.199681
B3GAT2 beta-1,3-glucuronyltransferase 2 0.198709
THAP3 THAP domain containing, apoptosis associated protein 3 0.198709
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.198709
GPX5 glutathione peroxidase 5 0.196139
HLA-B major histocompatibility complex, class I, B 0.194548
UROD uroporphyrinogen decarboxylase 0.194232
GPX4 glutathione peroxidase 4 0.1936
TPO thyroid peroxidase 0.193285
CXCL10 chemokine (C-X-C motif) ligand 10 0.192657
RETN resistin 0.189859
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.188938
CTGF connective tissue growth factor 0.187113
IL4 interleukin 4 0.18621
SYNM synemin, intermediate filament protein 0.185612
CD68 CD68 molecule 0.183541
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.183248
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.183248
STAT2 signal transducer and activator of transcription 2, 113kDa 0.182957
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.181222
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.17952
HIST1H1B histone cluster 1, H1b 0.17952
G6PC glucose-6-phosphatase, catalytic subunit 0.178682
CD1D CD1d molecule 0.177576
HSPG2 heparan sulfate proteoglycan 2 0.177301
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.176485
CHD1 chromodomain helicase DNA binding protein 1 0.175679
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.173057
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.172544
TERT telomerase reverse transcriptase 0.168617
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.166995
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.164571
LRRC38 leucine rich repeat containing 38 0.163729
A2M alpha-2-macroglobulin 0.161523
LZTS1 leucine zipper, putative tumor suppressor 1 0.160387
FKBP2 FK506 binding protein 2, 13kDa 0.160203